☆ 4.7 Article

Molecular Iodine Promoted Divergent Synthesis of Benzimidazoles, Benzothiazoles, and 2-Benzyl-3-phenyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazines

JOURNAL OF ORGANIC CHEMISTRY (2014)

Journal

JOURNAL OF ORGANIC CHEMISTRY

Volume 79, Issue 9, Pages 3821-3829

Publisher

AMER CHEMICAL SOC

DOI: 10.1021/jo5000797

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Categories

Chemistry, Organic

Funding

CSIR, New Delhi [BSC-0102: THUNDER]

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Abstract

An unprecedented formation of a new class of 2-benzyl-3-phenyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazines has been discovered during the course of benzimidazole and benzothiazole synthesis, through the molecular iodine-mediated oxidative cyclization with a new C-N and S-N bond formation at ambient temperature.

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