Article
Chemistry, Physical
Jinying Liu, Yu Zhao, Changli Zhao, Xiaoqiu Dou, Xiaoyu Ma, Shaokang Guan, Yu Jia, Chuanliang Feng
Summary: The study investigated the impact of H-bonding patterns on the chirality of supramolecular assemblies, by designing phenylalanine derivatives with different H-bonding groups. It was found that ester and amide groups can influence the stability and handedness direction of nanostructures.
Article
Biochemistry & Molecular Biology
Hongwen Mu, Yan Jin, Rongrong Zhao, Liming Wang, Ying Jin
Summary: In this study, bifunctional Takemoto's catalysts were used to catalyze the enantioselective Michael reaction of aminomaleimides with nitroolefins. The resulting products showed good yields and high enantiomeric excess.
Article
Chemistry, Multidisciplinary
Wen-Lei Xu, Wei-Ming Zhao, Ru-Xia Zhang, Jie Chen, Ling Zhou
Summary: The translation introduces a new and efficient method for synthesizing axially chiral aryl-C3-benzoindoles, explaining the success of the strategy in detail.
Review
Chemistry, Organic
Helene Pellissier
Summary: This review discusses the major advancements in the total synthesis of bioactive products using enantioselective organocatalytic domino/tandem reactions as key steps, including those based on asymmetric Michael-initiated domino reactions and aldol-initiated domino/tandem reactions.
CURRENT ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Meir Abuaf, Subhomoy Das, Yitzhak Mastai
Summary: Chiral polymeric particles (CPPs) have been extensively studied in recent years for their significance in pharmaceutical applications. In this study, nanosized CPPs were synthesized and applied as catalysts for direct asymmetric aldol reaction. The CPPs, prepared by miniemulsion or inverse miniemulsion methods using various chiral amino acid derivatives, were characterized by dynamic light scattering and scanning electron microscopy. The spherical nanoparticles with sizes between 250 and 400 nm and high chiral surface area served as catalysts in the aldol reaction at room temperature without additional solvent. Among them, l-tryptophan exhibited the highest enantiomeric excess (>86%) with similar catalytic performance for four times.
Article
Chemistry, Organic
Ekta Gupta, Narendra Kumar Vaishanv, Sandeep Kumar, Raja Krishnan Purshottam, Ruchir Kant, Kishor Mohanan
Summary: The practical enantioselective N-selective nitroso aldol reaction of alpha-methylmalonamates with a nitrosoarene is reported. The Takemoto thiourea catalyst was employed to induce enantioselectivity, leading to the formation of optically active oxyaminated malonamates in reasonably good yields.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Applied
Michela Lupi, Omar Salmi, Caterina Viglianisi, Stefano Menichetti
Summary: This article reports the conversion of N-thiophthalimido-arylphenothiazines 2 and triarylamines 3 to dithiabridged triarylamine hetero[4]helicenes 1 using catalytic amounts of chalcogen substituted Lewis Bases and hexafluoro isopropanol as hydrogen bond donor. The procedure provides good yields under mild reaction conditions without the need for excess Lewis Acids. It also presents a preliminary study on the control of the M and P absolute stereochemistry of helicenes 1 using enantiopure sulfur containing Lewis Bases from the natural chiral pool.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Weike Zou, Xueyan Lin, Eugene M. Terentjev
Summary: Liquid crystalline elastomers (LCEs) are considered promising for artificial muscles, but achieving their actuation requires macroscopic alignment of liquid-crystalline orientation, which has been challenging. A two-stage curing strategy has been dominant, posing difficulties in practice despite its successes.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Jun-Xi Wu, Partha Pratim Bag, Yan-Tong Xu, Li Gong, Chun-Ting He, Xiao-Ming Chen, Jie-Peng Zhang
Summary: A new type of catalyst support using hydrogen-bonded ultrathin nanosheets was developed, demonstrating high stability and electron modulation effects. This pseudo-porous catalyst support also showed potential for application in other metal phosphides.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Carmen Lopez-Leonardo, Adrian Saura-Sanmartin, Marta Marin-Luna, Mateo Alajarin, Alberto Martinez-Cuezva, Jose Berna
Summary: This study describes the synthesis of chiral mechanically interlocked molecules and explores their applications in catalysis and sensing. The results demonstrate that enantioenriched value-added compounds can be obtained through base-promoted cyclization.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Chanjuan Zhang, Philipp Gotico, Regis Guillot, Diana Dragoe, Winfried Leibl, Zakaria Halime, Ally Aukauloo
Summary: At the core of carbon monoxide dehydrogenase (CODH) active site, two metal ions and hydrogen bonding from amino acids facilitate the interconversion between CO2 and CO. A designed molecular catalyst with a bimetallic iron complex and hydrogen bonding interactions showed improved selectivity and stability in heterogeneous CO2 reduction to CO. X-ray structures revealed the compromise between rigidity and flexibility of the catalyst in accommodating CO2 capture, activation, and reduction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Zhe Chen, Liming Wang, Wenqin Tian, Ying Jin, Xin Qin
Summary: Takemoto's catalysts were used for the enantioselective Friedel-Crafts reaction, resulting in the synthesis of 3-aryl-3-hydroxyl-2-oxindoles with high yields (85-96%) and up to 99% ee. This methodology offers expanded substrate scope compared to previous examples catalyzed by cinchonidine thiourea.
MOLECULAR DIVERSITY
(2023)
Article
Materials Science, Multidisciplinary
Qingquan Song, Wenwen Wu, Yi Wang, Junrong Yu, Zuming Hu, Yan Wang
Summary: The addition of PEO as an additive significantly enhances the tensile strength of PMIA fibers by weakening hydrogen bonding and improving fiber orientation. However, heat resistance and flame retardancy remain largely unchanged. This modification method has both academic and industrial value.
ADVANCED FIBER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Tuende Farago, Attila M. M. Remete, Istvan Szatmari, Rita Ambrus, Marta Palko
Summary: This work focuses on the synthesis of novel organocatalysts derived from beta-amino acids to improve their catalytic characteristics. The enantioselectivity of the aldol reaction between isatin and acetone was tested using various reaction parameters. The results showed that organocatalyst 7 exhibited good enantioselectivity (up to 57% ee) in the presence of LiOH, and substrate screening achieved excellent findings (up to 99% ee). Additionally, a mechanochemical study was conducted to make the model reaction more environmentally friendly and sustainable.
Review
Chemistry, Organic
Yi-Ren Zhu, Jie Xu, Hui-Fang Jiang, Rui-Jing Fang, Yan-Jun Zhang, Lu Chen, Chen Sun, Fei Xiong
Summary: This article reviews the application of bifunctional sulfonamide as a hydrogen-bonding catalyst in asymmetric organocatalysis after 2011, highlighting asymmetric processes such as aldol reaction, Michael addition, Mannich reaction, desymmetrization, and cyclization.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Arindam Mukhopadhyay, Swati Jindal, Vijay Kumar Maka, Jarugu Narasimha Moorthy
Summary: The study explores the impact of N-heteroaryl rings on the spectrokinetic properties of photogenerated o-quinonoid colored reactive intermediates in pyridyl- and pyrimidylethynylated benzopyrans. It reveals that the modification of photochromic behaviors and spectrokinetic properties in the presence of acid is influenced by the relative proton affinities of N-heteroaryl rings and resonance effects relayed through the ethynyl spacers. This research demonstrates the unique opportunity to modulate both photochromic and acidochromic properties of benzopyrans by leveraging N-heteroaromatic rings.
Article
Chemistry, Inorganic & Nuclear
Swati Jindal, Jarugu Narasimha Moorthy
Summary: In this study, a novel class of linkers with zwitterionic characteristics, similar to naturally occurring amino acids, was used to construct functional MOFs. The resulting MOF, Zn-DMBI, demonstrated unique properties and the ability to interact with guest species through electrostatic interactions. By exfoliating the material into zwitterionic 2D metal-organic nanosheets (MONs), a palatable fluorescence was observed. Furthermore, the suspension of luminescent MONs (LMONs) in methanol enabled selective sensing of anions, with a particular focus on dihydrogen phosphate.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Soumen Payra, Navin Yadav, Jarugu Narasimha Moorthy
Summary: This study investigated the reaction pathways of aryl olefins and thiols in the presence of Oxone in different solvent systems, revealing two distinct reaction pathways leading to the synthesis of two different products.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Kanyashree Jana, Jarugu Narasimha Moorthy
Summary: The spatial disposition of three benzene rings in triptycene allows for 'homoconjugation', a contentious issue in the literature. Through the design and synthesis of a diagnostic photochromic molecular system, the persistence of a photogenerated colored o-quinonoid intermediate supports the operation of homoconjugation.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Keshaba N. Parida, Jarugu Narasimha Moorthy
Summary: This article introduces the development of improved IBX with enhanced solubility and reactivity in organic solvents. The design principles to eliminate the explosive attributes by manipulating the structure of IBX are discussed. A convenient oxidative transformation method using Oxone (R) catalyst is presented, and the applications of improved IBX in efficient oxidations are summarized.
Article
Chemistry, Multidisciplinary
Parag Tamuly, Farasha Sama, Jarugu Narasimha Moorthy
Summary: A layered metal-organic framework (MOF), Cd-BPDP, was synthesized using a metal-assisted self-assembly method. The MOF was then exfoliated into porous 2D metal-organic nanosheets (MONs) through ultrasonication and mechanical grinding techniques. The resulting MONs showed significant iodine capture ability, attributed to the increased surface area, charge-transfer complex formation, and reinforced binding of iodine through charge transfer.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Chemistry, Organic
Navin Yadav, Soumen Payra, Jarugu Narasimha Moorthy
Summary: A metal-free and green iodine-catalyzed protocol is described for the synthesis of unsymmetrical thiosulfonates. The reactions occur at room temperature and provide good-to-excellent yields of the desired products.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Chetna Yadav, Ajay Kumar Sahoo, Jarugu Narasimha Moorthy
Summary: In this study, two porous organic polymers (POPs) were synthesized and used to stabilize metal nanoparticles. By embedding metal nanoparticles into the POPs, recyclable catalysts were achieved, and it was also demonstrated that the POPs exhibited high selectivity for adsorbing clean fuel, hydrogen gas.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Kanyashree Jana, Jarugu Narasimha Moorthy
Summary: Regioisomeric naphthopyrans annulated with triptycene, Prox-NP and Dist-NP, exhibit different photochromic behaviors. Prox-NP produces a stable colored intermediate, Prox-NPQ, while Dist-NP does not. The rigid triptycene scaffold of Prox-NP leads to higher constraint and stability.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Organic
Kanyashree Jana, Debarghya Sarkar, Preeti Jaiswal, Jarugu Narasimha Moorthy
Summary: A set of donor-acceptor azahelical coumarins (DA-AHCs) with high fluorosolvatochromic shifts and high quantum yields in solution and solid states were designed and synthesized. The excited-state properties of these compounds were investigated, revealing the contribution of intramolecular charge transfer and crystal packing to their emission behaviors. The analysis showed that strengthened hydrogen bonding promoted quenching, efficient crystal packing promoted high emission, and loose crystal packing contributed to excited-state deactivation.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Navin Yadav, Sushil Ranjan Bhatta, Jarugu Narasimha Moorthy
Summary: This study demonstrates a visible light-mediated synthesis of hetero-arenes (isoquinolines, benzothiazoles, and quinazolines) through the use of isocyanides and inexpensive acyl peroxides. It is the first time that singlet-excited isocyanides have been shown to decompose acyl peroxides into aryl/alkyl radicals. The resulting radicals attack isocyanides, leading to the formation of imidoyl radicals which subsequently cyclize to generate heteroarene products. The protocol eliminates the need for external photocatalysts, oxidants, additives, and bases.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Alka Karn, Chetna Yadav, Ajay Kumar Sahoo, Jarugu Narasimha Moorthy
Summary: A porous organic polymer (POP) with carboxylic acid functionalities, known as Carboxy-POP, has been developed for efficient heterogeneous catalytic reactions. The catalyst exhibits high catalytic activity, easy operation, high yields, short reaction times, and good recyclability.
Article
Chemistry, Organic
Navin Yadav, Soumen Payra, Parag Tamuly, Jarugu Narasimha Moorthy
Summary: In this study, the synthesis of beta-hydroxysulfones instead of beta-ketosulfones was selectively demonstrated using dye-sensitized photocatalysis. The reaction utilized inexpensive and readily available olefins and sulfonyl hydrazides/N-hydroxy sulfonamides in the presence of oxygen. It was found that the hydroxysulfonylation reaction, which employed rose bengal as a photocatalyst and dioxygen as an oxidant, selectively produced secondary and tertiary beta-hydroxysulfones in good yields. The formation of beta-hydroxysulfones and beta-ketosulfones was shown to proceed through different routes depending on the concentration of oxygen.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Swati Jindal, Gulshan Anjum, Vijay Kumar Maka, Jarugu Narasimha Moorthy
Summary: A water-stable In-MOF with a conformationally-flexible tetraacid linker exhibited significantly enhanced solid-state fluorescence quantum yield due to rigidification by metalation. Grinding of the In-MOF led to a drastic enhancement in fluorescence intensity, correlated with particle size reduction and particle aggregation. The study also demonstrated the sensing capability of metal ions by suspended In-MOF particles in water, showing both mechanoluminescence and aggregation-enhanced emission of MOF particles for the first time.
Article
Nanoscience & Nanotechnology
Swati Jindal, Vijay Kumar Maka, Gulshan Anjum, Jarugu Narasimha Moorthy
Summary: A fluorescent 4-connecting bisimidazole-tetraacid linker was designed to access a metal-organic layered material with enhanced fluorescence in its 2D metal-organic framework nanosheets generated by solvent-assisted exfoliation. The suspension of 2D MONs serves as an efficient turn-on fluorescent material for sensing of the toxic nerve agent mimics, with a detection limit of approximately 0.52 ppm for diethyl chlorophosphate.
ACS APPLIED NANO MATERIALS
(2021)