Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 4, Pages 1177-1179Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo1023393
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A general method for the synthesis of 1,3,5-trisubstituted 1,2,4-triazoles has been developed from reaction of carboxylic acids, primary amidines, and monosubstituted hydrazines. This highly regioselective and one-pot process provides rapid access to highly diverse triazoles.
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