Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 6, Pages 1918-1921Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo102372m
Keywords
-
Categories
Funding
- Natural Science and Engineering Research Council of Canada (NSERC)
Ask authors/readers for more resources
The N,O-dimethyloxyamine-N-glycosides are introduced as anomerically protected building blocks for carbohydrate synthesis. These N-glycosides are stable to a variety of protecting group manipulations including acylation, alkylation, silylation, and acetal formation. The alkoxyamine-N-glycosides can be cleaved selectively with N-chlorosuccinimide to give the desired hemiacetals in excellent yield. Furthermore, these N-glycosides are stable to the activation conditions required for glycosylation using thioglycoside and trichloroacetimidate glycosyl donors suggesting N,O-dialkoxyamine-N-glycosides will be useful for complex oligosaccharide synthesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available