4.7 Article

Pd-Catalyzed Asymmetric Allylic Etherizations with Oximes by Chiral Alkene-Phosphine Ligands

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 76, Issue 15, Pages 6401-6406

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo200925q

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Funding

  1. National Science Foundation of China [20802079, 21072194]
  2. National Basic Research Program of China [2010CB833 300]
  3. Scientific Research Foundation for the Returned Overseas Chinese Scholars

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Palladium-catalyzed asymmetric allylic etherizations with a variety of mimes as nucleophiles utilizing a chiral alkene-phosphine hybrid ligand have been successfully achieved for the first time to afford the optical active oxime ethers in high yields with good to excellent enantioselectivities.

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