Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 3, Pages 963-965Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo902383b
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Funding
- Japan Society for the Promotion of Science (JSPS)
- Global COE Program
- University of Tokyo, MEXT, Japan
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A chiral calcium complex was found to be effective for the Mannich reactions of malonates with N-Boc imines. The desired adducts were obtained in excellent yields (up to 95%) with moderate to good enantioselectivities (up to 77% ee).
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