Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 75, Issue 11, Pages 3863-3866Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo100397a
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Funding
- National Nature Science Foundation of China [20772024, 20802016]
- Program for New Century Excellent Talents in University of Ministry of Education [NCET-09-0122]
- Program for Innovative Research Team in University of Henan Province [2008IRTSTHN002]
- Henan National Nature Science Foundation [092300410226]
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A novel and efficient synthetic method has been developed Oar the preparation of chiral acyclic nucleosides with a chiral amino side chain by Mitsunobu reaction between nucleoside bases and protected L-serine. This method suggests a potentially more efficient and complementary process to acquire chiral acyclic nucleosides.
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