Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 13, Pages 5155-5158Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo800749t
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Funding
- NIGMS NIH HHS [R01 GM063723, R01 GM063723-06S1, GM63723] Funding Source: Medline
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An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and piperidine rings using an organo-catalyzed, intramolecular heteroatom Michael addition is described. Application to the enantioselective synthesis of homoproline, homopipecolic acid, and pelletierine has been accomplished.
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