Article
Gastroenterology & Hepatology
Chang Chen, Xiang Zhang, Zhi-Qiang Cheng, Bin-Bin Zhang, Xin Li, Ke-Xin Wang, Yong Dai, Yan-Lei Wang
Summary: The improved gunsight technique in enterostomy closure surgery can decrease the incision infection rate, shorten the postoperative hospital stay, reduce wound tension, and provide better wound cosmetic effects compared to traditional interrupted suture.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Health Care Sciences & Services
Elias Polykandriotis, Jonas Daenicke, Anil Bolat, Jasmin Gruener, Dirk W. Schubert, Raymund E. Horch
Summary: This study reviewed the physical properties of different suturing materials under mechanical load and found that the linear tensile strength decreased significantly with the increase in crushing load cycles. Different materials also exhibited varying resistance to crush loading.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Agriculture, Dairy & Animal Science
Dimitrios B. B. Balomenos, Pagona G. G. Gouletsou, Apostolos D. D. Galatos
Summary: The study aimed to compare the healing process of canine skin using staples, tissue glue, and intradermal sutures. The researchers found that the intradermal suture pattern had a better cosmetic appearance and clinical evaluation compared to glue, while there was no significant difference between intradermal sutures and staples. The study concluded that staples should be preferred when time is a crucial factor.
Article
Surgery
Yong-fei Wang, Ya-ting Yang, Zong-an Chen, Xiao-li Wu
Summary: The CHN.WU wound suture technique uses barbed sutures to close high-tension wounds without breaking through the epidermis, ensuring high efficiency and satisfactory cosmetic appearance.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Polymer Science
Wen-Can Huang, Yongjun He, Wei Wang, Xiangzhao Mao
Summary: This study reports a multifunctional film (MFF) composed of self-crosslinked aldehyde-functionalized chitosan and crosslinked poly(acrylic acid), which is further coordinated with silver ions. The MFF exhibits enhanced toughness, stretchability, and antibacterial properties, making it a promising alternative tissue adhesive. In vivo studies demonstrate that the MFF can easily adhere to wet and dynamic tissue surfaces, providing superior hemostasis and sealing properties.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Ruinan Hao, Zhuoyi Cui, Xindan Zhang, Ming Tian, Liqun Zhang, Feng Rao, Jiajia Xue
Summary: Skin wound healing is a dynamic and complex process, and effectively treating wounds and regenerating damaged skin is a clinical challenge. Hydrogels, through rational design and preparation, have the potential to play a significant role in skin wound healing. This mini review introduces the design and construction of hydrogels, summarizes the recent research progress on functional bioactive hydrogel dressings for skin wound healing, and highlights the design strategies of responsive hydrogels to physical stimuli. The review also provides perspectives on future directions and challenges of functional hydrogels for skin wound healing.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Yi Li, Hangqi Luo, Yue Li, Peipei Huang, Jie Xu, Jian Zhang, Peihan Cai, Huacheng He, Jiang Wu, Xiaokun Li
Summary: Functional degradable sutures with controlled release of basic fibroblast growth factor (bFGF) were developed to enhance wound healing. The suture showed prolonged bFGF release, improved cell adhesion and proliferation, accelerated wound closure, and facilitated skin mechanical restoration.
MATERIALS & DESIGN
(2023)
Article
Chemistry, Physical
Carlota Castro-Gaspar, Maria Victoria Olmedo-Gaya, Maria Nuria Romero-Olid, Maria Jesus Lisbona-Gonzalez, Marta Vallecillo-Rivas, Candela Reyes-Botella
Summary: The study demonstrates that the use of tissue adhesive cyanoacrylate in oral surgery significantly reduces operative time and postoperative bleeding within the first 24 hours compared to sutures.
Article
Chemistry, Multidisciplinary
Yaodong Zhao, Bingcheng Yi, Jilin Hu, Dongjie Zhang, Guotai Li, Yun Lu, Qihui Zhou
Summary: In order to prevent microbial invasion, inhibit scar formation, and promote wound healing, a thermo-responsive and tissue-adhesive hydrogel dressing was developed. This dressing, based on N-dimethylbisacrylamide (NIPAM) and glutaraldehyde (GTA) cross-linked hyaluronic acid (HA), showed self-contraction and tissue adhesiveness, aiding wound closure via mechanical stretch. It also demonstrated hemocompatibility and cytocompatibility, accelerating wound healing. In vivo experiments using a mouse model showed that the hydrogel dressing achieved sutureless closure at the early stage of wound healing and promoted healing by reducing inflammation, promoting angiogenesis, and reducing collagen deposition.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Engineering, Biomedical
Rui Yu, Meng Li, Zhenlong Li, Guoying Pan, Yuqing Liang, Baolin Guo
Summary: A novel supramolecular poly(N-isopropylacrylamide) hybrid hydrogel dressing with thermal contraction and tissue adhesion properties, as well as multiple mechanical and biological properties, is developed to achieve noninvasive wound closure and enhance wound healing simultaneously.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Xiong-Xin Lei, Juan-Juan Hu, Chen-Yu Zou, Yan-Lin Jiang, Long-Mei Zhao, Xiu-Zhen Zhang, Ya-Xing Li, An-Ni Peng, Yu-Ting Song, Li-Ping Huang, Jesse Li-Ling, Hui-Qi Xie
Summary: This study reports a two-component in-situ hydrogel prepared from maleimide-based oxidized sodium alginate and sulfhydryl carboxymethyl-chitosan, which gelates mainly based on click chemistry and Schiff base reaction. The hydrogel showed short gelation time, outstanding tissue adhesion, favorable hemostatic properties, and good biocompatibility. Animal experiments demonstrated that the hydrogel provides appropriate mucosal uplift height and durable maintenance time, and significantly accelerates wound healing and repair.
BIOACTIVE MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Yuqing Liang, Huiru Xu, Zhenlong Li, Aodi Zhangji, Baolin Guo
Summary: This article introduces a multifunctional hydrogel adhesive prepared by a bioinspired dynamic bond cross-linking method, which can be used for seamless wound closure and wound healing. The hydrogel has sufficient mechanical and adhesive strength, as well as injectability and self-healing capacity, which can effectively close wounds and repeatedly close reopened wounds. In addition, it also has good biocompatibility, antibacterial activity, and hemostatic effect.
NANO-MICRO LETTERS
(2022)
Review
Pharmacology & Pharmacy
Fabiola V. Borbolla-Jimenez, Sheila I. Pena-Corona, Sonia J. Farah, Maria Teresa Jimenez-Valdes, Emiliano Pineda-Perez, Alejandra Romero-Montero, Maria Luisa Del Prado-Audelo, Sergio Alberto Bernal-Chavez, Jonathan J. Magana, Gerardo Leyva-Gomez
Summary: Wound healing is a complex process involving four phases: hemostasis, inflammation, proliferation, and remodeling. Polymeric films have been widely used as wound dressings due to their biocompatibility, low immunogenicity, ease of application, and gas exchange capabilities. Among various methods for designing polymeric films, solvent casting is a reliable and cost-effective technique. This review focuses on polymeric dressings obtained using solvent casting, discussing the manufacturing factors necessary for effective wound dressing performance.
Review
Emergency Medicine
Wenhui Liu, Lihua Zu, Shanzheng Wang, Jingyao Li, Xiaoyuan Fei, Meng Geng, Chunlei Zhu, Hui Shi
Summary: This review summarizes the design approaches and applications of smart biomaterials in wound healing. By controlling infection and inflammation, and promoting tissue regeneration, biomaterials play a crucial role in wound healing.
Article
Engineering, Biomedical
Shen Guo, Minghao Yao, Dan Zhang, Yuanmeng He, Rong Chang, Yikun Ren, Fangxia Guan
Summary: The study developed a one-step synthetic hydrogel based on quaternized chitosan, tannic acid, and ferric iron, with high adhesiveness, antibacterial activity, and photothermal property. In mouse models, it showed effective wound closure and accelerated wound healing, demonstrating great potential for clinical applications in wound management.
ADVANCED HEALTHCARE MATERIALS
(2022)
