Article
Biotechnology & Applied Microbiology
Shahrokh Hatefi, Milad Sh Etemadi, Javad Alizargar, Venous Behdadipour, Khaled Abou-El-Hossein
Summary: The application of Distraction Osteogenesis (DO) techniques in reconstruction surgeries is advantageous with fewer side effects. However, the development of automatic devices for controlled continuous force still requires further research. A two-axis continuous distractor is proposed for mandibular reconstruction, meeting the current requirements.
BIOENGINEERING-BASEL
(2022)
Article
Biotechnology & Applied Microbiology
Francisco Vale, Joana Queiroga, Flavia Pereira, Madalena Ribeiro, Filipa Marques, Raquel Travassos, Catarina Nunes, Anabela Baptista Paula, Ines Francisco
Summary: A new dental-anchored distractor was introduced to correct mandibular retrognathia, showing improved patient tolerance and avoiding the limitations of conventional surgical treatment.
BIOENGINEERING-BASEL
(2021)
Article
Biotechnology & Applied Microbiology
Shahrokh Hatefi, Javad Alizargar, Yimesker Yihun, Milad Etemadi Sh, Nan-Chen Hsieh, Khaled Abou-El-Hossein
Summary: Distraction osteogenesis is an effective method for bone deficiency reconstruction in the oral and maxillofacial area. This study proposes a hybrid distractor that combines motor-driven and hydraulic techniques to achieve continuous distraction and precise control of the bone segment position. The modeling and experimental results demonstrate that the hybrid distractor meets all the requirements for continuous distraction osteogenesis in humans.
BIOENGINEERING-BASEL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Seyit Ahmet Ozturk, Siddik Malkoc, Umit Yolcu, Zehra Ileri, Ozge Celik Guler
Summary: The study found that MMDO and RME procedures provide an effective non-extraction treatment alternative for transverse maxillomandibular deficiency, improving facial soft tissue profiles.
ANGLE ORTHODONTIST
(2021)
Review
Surgery
Yehuda Chocron, Natasha Barone, Dino Zammit, Mirko S. Gilardino
Summary: Mandibular distraction osteogenesis (MDO) is an effective procedure for patients with Robin Sequence, providing long-term respiratory outcomes and avoiding tracheostomies. However, complications such as dental and nerve injuries are important considerations that require long-term follow-up. Neonatal patients do not appear to have a higher risk of complications.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Cell Biology
Weidong Jiang, Peiqi Zhu, Fangfang Huang, Zhenchen Zhao, Tao Zhang, Xiaoning An, Fengchun Liao, Lina Guo, Yan Liu, Nuo Zhou, Xuanping Huang
Summary: Distraction osteogenesis (DO) is a method used to treat large bone defects in oral and maxillofacial surgery. This study found that the m(6)A modification level increases significantly during DO and is also elevated during EPC angiogenesis under hypoxic conditions, along with an increase in METTL3 levels. Inhibiting METTL3 in EPCs suppresses various angiogenic activities, while overexpression of METTL3 enhances these activities, suggesting that METTL3 accelerates bone regeneration during DO by promoting EPC angiogenesis through the PI3K/AKT pathway.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Suen A. N. Lie, Britt H. B. T. Engelen, Veronique C. M. L. Timmer, Nico M. P. Vrijens, Paolo Asperio, Peter A. W. H. Kessler
Summary: The aim of this study was to present the first experience with intermolar mandibular distraction osteogenesis (IMDO). A retrospective case series of 20 patients showed satisfactory outcomes with Class I occlusion achieved, although some undesirable effects and open questions regarding long-term stability and root fractures were observed.
APPLIED SCIENCES-BASEL
(2021)
Review
Dentistry, Oral Surgery & Medicine
S. Dasukil, S. Verma, K. K. Boyina, A. K. Jena
Summary: Distraction osteogenesis is a popular treatment for lengthening the mandible, but there is a rare risk of distractor breakage during the procedure. Limited literature reports exist regarding distractor breakage, indicating a need for further research on etiology and prevention measures.
JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Clinical Neurology
Rashi Kochhar, Vikash Modi, Neranjan de Silva, Seyni Gueye-Ndiaye, Jay M. Neugarten, Mary J. Ward, Linda M. Gerber, Anjile An, Elizabeth Mauer, Haviva Veler
Summary: This study is the first case series that utilizes polysomnography (PSG) to guide mandibular distraction osteogenesis in patients with micrognathia. The results demonstrate the need for jaw overcorrection to resolve obstructive sleep apnea (OSA).
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Review
Orthopedics
Abdulnassir Ali, Ying Ren, Chun-Hao Zhou, Jia Fang, Cheng-He Qin
Summary: This case presented an unprecedented tibial bone lengthening of 33.5cm for the management of chronic osteomyelitis and bone defects in the right leg. Limb reconstruction with distraction osteogenesis allowed the patient to avoid amputation and partially restore limb function, enabling independent walking after 3 years.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Surgery
Mychajlo S. Kosyk, Anna R. Carlson, Zachary D. Zapatero, Christopher L. Kalmar, Christopher M. Cielo, Janet Lioy, Scott P. Bartlett, Jesse A. Taylor, Jordan W. Swanson
Summary: The study demonstrates that mandibular distraction osteogenesis (MDO) can effectively treat severe tongue-based airway obstruction (TBAO) in nonmicrognathic patients, reducing the need for tracheostomy. However, feeding support is still required in most patients at 6 months postoperatively.
ANNALS OF PLASTIC SURGERY
(2022)
Article
Pediatrics
Zhe Mao, Ricardo Battaglino, Jiawei Zhou, Yingqiu Cui, Mayank Shrivastava, Gabriel Tian, Faezeh Sahebdel, Liang Ye
Summary: The study found that mandibular distraction osteogenesis (MDO) can help infants with severe Robin Sequence (RS) to reach a normal weight. Early intervention with MDO is recommended for early weight gain. The impact of MDO timing on weight gain varies.
Article
Medicine, Research & Experimental
Zahrah Taufique, Bridget Ebert, Emily C. Smith, Zavala Hanan, Andrew R. Scott, Brianne B. Roby
Summary: A retrospective study on 69 patients with RS undergoing MDO surgery showed that newborns weighing less than 3 kg experience similar rates of success and complications as larger infants. There was no significant correlation between weight and age with unfavorable postoperative outcomes.
Review
Chemistry, Multidisciplinary
Fotis Vogiatzis, Petros Roussos, Ioannis Doulis, Georgia Palikaraki, Panagiotis Christopoulos, Iosif Sifakakis
Summary: This systematic review examines the effects of surgically assisted rapid palatal expansion (SARPE) on facial soft tissues. The included studies suggest a post-surgical increase in alar width and alar base width. However, due to methodological limitations and high risk of bias, quantitative synthesis was not feasible.
APPLIED SCIENCES-BASEL
(2022)
Review
Dentistry, Oral Surgery & Medicine
T. C. Nino-Sandoval, E. D. R. Rodrigues, B. C. Vasconcelos
Summary: The study aimed to review the need for a latency period in distraction osteogenesis, with results showing uncertainties and potential biases that require caution when interpreting for clinical applications.
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY
(2021)