Article
Environmental Sciences
Donrawee Waeyeng, Tanaporn Khamphaya, Phisit Pouyfung, Udomratana Vattanasit, Supabhorn Yimthiang
Summary: This cross-sectional study examined blood lead levels and related risk factors among non-occupationally exposed pregnant women from the general population in Nakhon Si Thammarat province, Southern Thailand. The results showed that pregnant women who were not employed in lead-related occupations still had lead in their bodies. Education level was the only demographic factor associated with high blood lead levels, and systolic blood pressure was also found to be associated. These findings indicate the importance of health education and interventions to prevent lead exposure, especially for pregnant women and children.
Article
Environmental Sciences
Mona Mohamed Taha, Nagat Mohamed Amer, Safia Beshir, Heba Mahdy-Abdallah
Summary: The study investigated the relationship between hearing loss and blood pressure variation in textile workers, finding an association between HSP70 genotypes and hypertension, with smoking also influencing the results.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Changaiz Khan, Muhammad Yasir Abdur Rehman, Riffat Naseem Malik
Summary: Exposure to heavy metals can result in oxidative stress, with dust in the workplace being a significant source of metal exposure. A study on chromite mine workers found elevated levels of metals in dust-exposed workers, correlating with increased oxidative stress.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Toxicology
Changmao Long, Guiping Hu, Pai Zheng, Tian Chen, Zekang Su, Yali Zhang, Chunguang Ding, Fangda Peng, Shanfa Yu, Tiancheng Wang, Guang Jia
Summary: This study utilized UPLC-MS non-targeted metabolomics to analyze serum metabolic changes in chromate exposure workers and controls, revealing decreases in 13 metabolites and increases in 41 metabolites related to arginine, proline, and glycerophospholipid metabolism. Additionally, significant negative correlations were found between blood Cr level and certain metabolites, primarily among male subgroups. The potential influence of diet as a confounding factor was highlighted, requiring further verification in future research.
TOXICOLOGY LETTERS
(2021)
Review
Environmental Sciences
Lara A. Oliveira, Regina P. El Dib, Drielle B. S. Figueiredo, Leandro G. Braz, Mariana G. Braz
Summary: This study reviewed 18 observational studies and found that occupational exposure to inhalational anesthetics may be associated with spontaneous abortion, especially among professionals who work for longer periods without proper ventilation facilities.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Huan Song, Yanan Shang, Fang Fang, Catarina Almqvist, Nancy L. Pedersen, Patrik K. E. Magnusson, Henrik Larsson, Unnur A. Valdimarsdottir
Summary: Losing a twin, especially a monozygotic one, is associated with increased mortality among the surviving twin, particularly due to unnatural causes.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Mohammad Hasan Rabiee, Mostafa Ghanei, Hossein Amini, Aliasghar Akhlaghi
Summary: This study investigated the long-term mortality rate among civilian people exposed to mustard gas (MG) during the Iran-Iraq war in Sardasht, Iran after 32 years. The results showed that acute exposure to MG, even without protective clothing and masks, does not increase all-cause mortality after 32 years if accompanied by special and ongoing care for those exposed. However, the observed deaths due to respiratory diseases were higher than expected.
Article
Environmental Sciences
Olga S. Arvaniti, Olga-Ioanna Kalantzi
Summary: This review examines determinants of flame retardants (FRs) in non-occupationally exposed individuals, finding associations between human exposure and demographic factors, as well as behavioral and environmental factors. However, methodological differences among studies did not reveal a complete pattern of human exposure routes.
Article
Biochemistry & Molecular Biology
Katarzyna Gajewska, Marzena Laskowska, Agostinho Almeida, Edgar Pinto, Katarzyna Skorzynska-Dziduszko, Anna Blazewicz
Summary: The study compared blood lead levels in preeclamptic women with healthy pregnant women, finding significantly higher BLL in the PE group. Furthermore, BLL showed a significant positive relationship with the presence of PE.
Article
Environmental Sciences
Nihal Kilinc, Mehmet Onbasilar, Akin Cayir
Summary: This study investigated the plasma concentration of cell-free nucleic acids in radiology workers and found that the concentration of ccfRNA was significantly correlated with working time and imaging number, while total working time was significantly associated with total ccfRNA concentration. These findings suggest that total RNA can be used to predict radiation exposure risk and that working time and imaging parameters can alter the level of free nucleic acids.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Infectious Diseases
Rui Shen, Ai-Ling Wang, Xiao-Ping Pan, Ya-Ping Qiao, Qian Wang, Xiao-Yan Wang, Shui-Ling Qu, Tong Zhang
Summary: The study found that Chinese HIV-exposed children have low vaccination coverage, mainly due to factors such as perinatally acquired HIV, early infant HIV diagnosis, and mothers' education levels. Therefore, interventions should be developed targeting minority ethnic HIV-exposed children with low maternal education levels, and more attention should be paid to early HIV diagnosis to increase access to immunization.
INFECTIOUS DISEASES OF POVERTY
(2021)
Article
Environmental Sciences
Lorena Diaz de Leon-Martinez, Jose Moises Grimaldo-Galeana, Luz Eugenia Alcantara-Quintana, Fernando Diaz-Barriga, Francisco Javier Perez-Vazquez, Rogelio Flores-Ramirez
Summary: Quarrying is a hazardous informal economic activity that puts workers and their families at risk due to high toxicity and lack of protection. This study evaluates the respiratory health of artisan stonemasons in San Luis Potosi, Mexico and finds that they are highly exposed to pneumotoxic pollutants and markers of inflammation, suggesting a high risk of developing silicosis.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Infectious Diseases
Ili Margalit, Giusy Tiseo, Marco Ripa, Vanni Borghi, Hefziba Green, Virginie Prendki, Niccolo Riccardi, Giovanni Battista Perego, Alessandro Grembiale, Laura Galli, Marco Tinelli, Antonella Castagna, Cristina Mussini, Marco Falcone, Dafna Yahav
Summary: This study assessed the effect of remdesivir on COVID-19 mortality among elderly individuals using real-world data. The results showed that remdesivir reduced mortality in patients requiring oxygen support or non-invasive mechanical ventilation, but no association was found among patients necessitating invasive mechanical ventilation.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2023)
Article
Public, Environmental & Occupational Health
Julie Elbaek Pedersen, Katrine Strandberg-Larsen, Michael Andersson, Johnni Hansen
Summary: This study found that occupational exposure to diesel exhaust may increase the risk of early-onset estrogen receptor-negative breast tumors in women, especially in those under 50 years old. Further research is needed to explore this association.
SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH
(2021)
Article
Biophysics
Margaret M. Sugg, Jennifer D. Runkle, Kirstin Dow, Janice Barnes, Scott Stevens, John Pearce, Brian Bossak, Scott Curtis
Summary: This study aims to investigate the heat exposure and resulting heat strain among outdoor workers, specifically in the humid coastal climate of Charleston, USA. The research found significant heterogeneity in heat index exposure among individuals and identified associations between heat strain occurrence and personal heat metrics. Furthermore, the study compared different exposure metrics and found that raster-derived urban heat island measurements differed from individually heat index exposure measurements. Real-time monitoring was highlighted as a valuable tool for understanding temperature-health trends and behaviors during extreme thermal events.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2022)
Article
Infectious Diseases
Kristal J. Aaron, Ilene Brill, Zenoria Causey-Pruitt, Kerry Murphy, Michael Augenbraun, Seble Kassaye, Joel E. Milam, Dominika Seidman, Audrey L. French, Stephen J. Gange, Adaora A. Adimora, Anandi N. Sheth, Margaret A. Fischl, Barbara Van Der Pol, Jeanne Marrazzo, Mirjam-Colette Kempf, Jodie Dionne-Odom
Summary: Syphilis rates among women in the USA have more than doubled between 2014 and 2018. Factors associated with syphilis infection among women in the Women's Interagency HIV Study (WIHS) include age, hepatitis C seropositivity, and problem alcohol use. Targeted prevention efforts should focus on women with these risk factors.
SEXUALLY TRANSMITTED INFECTIONS
(2022)
Article
Immunology
Mohamed El-Far, Madeleine Durand, Isabelle Turcotte, Etienne Larouche-Anctil, Mohamed Sylla, Sarah Zaidan, Carl Chartrand-Lefebvre, Remi Bunet, Hardik Ramani, Manel Sadouni, Irina Boldeanu, Annie Chamberland, Sylvie Lesage, Jean-Guy Baril, Benoit Trottier, Rejean Thomas, Emmanuel Gonzalez, Ali Filali-Mouhim, Jean-Philippe Goulet, Jeffrey A. Martinson, Seble Kassaye, Roksana Karim, Jorge R. Kizer, Audrey L. French, Stephen J. Gange, Petronela Ancuta, Jean-Pierre Routy, David B. Hanna, Robert C. Kaplan, Nicolas Chomont, Alan L. Landay, Cecile L. Tremblay
Summary: This study identified an HIV-specific atherosclerotic inflammatory signature involving specific IL-32 isoforms, regulated by the SCFA caproic acid, which may offer new potential therapies for preventing CVD in ART-treated PLWH.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Immunology
Mohamed El-Far, David B. Hanna, Madeleine Durand, Etienne Larouche-Anctil, Mohamed Sylla, Carl Chartrand-Lefebvre, Guy Cloutier, Jean Philippe Goulet, Seble Kassaye, Roksana Karim, Jorge R. Kizer, Audrey L. French, Stephen J. Gange, Jason M. Lazar, Howard N. Hodis, Jean-Pierre Routy, Petronela Ancuta, Nicolas Chomont, Alan L. Landay, Robert C. Kaplan, Cecile L. Tremblay
Summary: The study investigated the potential of interleukin 32 (IL-32) as a biomarker for subclinical carotid artery atherosclerosis in women living with HIV. Plasma IL-32 levels were higher in women living with HIV compared to those without HIV. Although plasma IL-32 levels did not differ significantly between carotid artery plaque cases and controls, expression of IL-32 isoforms was significantly higher in cases, indicating a potential role of IL-32 isoforms as cardiovascular disease biomarkers.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2021)
Article
Immunology
Brandilyn A. Peters, Jee-Young Moon, David B. Hanna, Olaf Kutsch, Margaret Fischl, Caitlin A. Moran, Adaora A. Adimora, Stephen Gange, Nadia R. Roan, Katherine G. Michel, Michael Augenbraun, Anjali Sharma, Alan Landay, Seema Desai, Robert C. Kaplan
Summary: Persistent CD4(+) T-cell activation and exhaustion may contribute to increased long-term mortality risk in women with HIV, independent of HIV disease progression.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Hematology
Namita Kumari, Mehdi Nouraie, Asrar Ahmad, Hatajai Lassiter, Javed Khan, Sharmin Diaz, Nowah Afangbedji, Songping Wang, Patricia E. Houston, Tatiana Ammosova, Miguel de Mulder Rougvie, Sohail Rana, Douglas F. Nixon, Kathryn Anastos, Jason Lazar, Audrey L. French, Stephen Gange, Adaora A. Adimora, M. Neale Weitzmann, Margaret Fischl, Mirjam-Colette Kempf, Seble Kassaye, James G. Taylor, Sergei Nekhai
Summary: Individuals with sickle cell trait (SCT) exhibit a restriction of HIV-1 infection characterized by higher levels of HO-1 and lower levels of HIV-1 replication. This suggests that factors like HO-1 and RNR2 may limit HIV-1 pathogenicity among those with SCT.
Article
Immunology
Kathleen A. McGinnis, Amy C. Justice, Richard D. Moore, Michael J. Silverberg, Keri N. Althoff, Maile Karris, Viviane D. Lima, Heidi M. Crane, Michael A. Horberg, Marina B. Klein, Stephen J. Gange, Kelly A. Gebo, Angel Mayor, Janet P. Tate
Summary: The updated VACS Index 2.0 can reliably estimate all-cause mortality probability among persons with HIV in North America. This study found that predicted mortality rates largely overlapped with observed mortality rates among diverse HIV cohorts, indicating good calibration of the index.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Immunology
Daniel E. Sack, Stephen J. Gange, Keri N. Althoff, April C. Pettit, Asghar N. Kheshti, Imani S. Ransby, Jeff J. Nelson, Megan M. Turner, Timothy R. Sterling, Peter F. Rebeiro
Summary: Using maps to analyze the geographic distribution of HIV-infected individuals is crucial for guiding public health interventions. Compared to traditional choropleth maps, density-adjusted cartograms provide a more accurate visualization of high-burden and low-burden areas, improving the interpretation of visually highlighting regions of interest.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2022)
Article
Multidisciplinary Sciences
Douglas M. Wallace, Maria L. Alcaide, William K. Wohlgemuth, Deborah L. Jones Weiss, Claudia Uribe Starita, Sanjay R. Patel, Valentina Stosor, Andrew Levine, Carling Skvarca, Dustin M. Long, Anna Rubtsova, Adaora A. Adimora, Stephen J. Gange, Amanda B. Spence, Kathryn Anastos, Bradley E. Aouizerat, Yaacov Anziska, Naresh M. Punjabi
Summary: The prevalence of RLS was similar in men with and without HIV in the study. Screening for RLS may be considered among people with HIV with insomnia and with long-standing disease.
Article
Public, Environmental & Occupational Health
Henna Budhwani, C. Ann Gakumo, Ibrahim Yigit, Whitney S. Rice, Faith E. Fletcher, Samantha Whitfield, Shericia Ross, Deborah J. Konkle-Parker, Mardge H. Cohen, Gina M. Wingood, Lisa R. Metsch, Adaora A. Adimora, Tonya N. Taylor, Tracey E. Wilson, Sheri D. Weiser, Oluwakemi Sosanya, Lakshmi Goparaju, Stephen Gange, Mirjam-Colette Kempf, Bulent Turan, Janet M. Turan
Summary: This mixed-methods study explores the impact of provider communication and patient health literacy on HIV continuum of care outcomes among women living with HIV in the United States. Qualitative themes highlighted the importance of respect, non-verbal cues, and the negative effects of condescending communication from providers. Quantitative mediation analyses indicated that higher health literacy was associated with improved patient-provider interactions, increased trust in HIV providers, better medication adherence, and fewer missed clinical visits. Enhancing provider communication and patient health literacy could have a positive impact on the HIV continuum of care.
Article
Immunology
Richard J. Wang, Mehdi Nouraie, Ken M. Kunisaki, Laurence Huang, Phyllis C. Tien, Kathryn Anastos, Neha Bhandari, Surya P. Bhatt, Hector Bolivar, Sushma K. Cribbs, Robert Foronjy, Stephen J. Gange, Deepa Lazarous, Alison Morris, M. Bradley Drummond
Summary: This study investigated the association between HIV infection and differences in lung function in women. The results showed that HIV infection was associated with impaired respiratory gas exchange in women, and among women with HIV, lower nadir CD4+ cell counts and hepatitis C infection were associated with decreased respiratory gas exchange.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Annelys Roque Gardner, Yifei Ma, Peter Bacchetti, Jennifer C. Price, Mark H. Kuniholm, Audrey L. French, Stephen Gange, Adaora A. Adimora, Howard Minkoff, Seble Kassaye, Igho Ofotokun, William Rosenberg, Andrea A. Z. Kovacs, Phyllis C. Tien
Summary: This study investigated the trajectory of liver fibrosis in women with HIV/HCV coinfection. The results showed an initial rise in serum biomarkers of liver fibrosis followed by declines within the year before starting HCV treatment. However, there appeared to be a lack of decline in these biomarkers beyond 1 year after HCV cure.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Psychiatry
Leah H. Rubin, Mandakh Bekhbat, Susie Turkson, C. Christina Mehta, Pauline M. Maki, Kathryn Anastos, Deborah Gustafson, Amanda B. Spence, Joel Milam, Felicia C. Chow, Kathleen Weber, Gayle Springer, Stephen J. Gange, Gretchen N. Neigh
Summary: This study evaluated the impact of HIV infection and age on the association between GCR function and cognition in women. The results suggest that HIV infection and age may modify the influence of GCR, potentially through epigenetic modification of target genes.
PSYCHOSOMATIC MEDICINE
(2022)
Article
Geriatrics & Gerontology
K. M. Erlandson, S. Langan, J. E. Lake, J. Sun, A. Sharma, S. Adrian, A. Scherzinger, F. Palella, L. Kingsley, S. J. Gange, P. C. Tien, M. T. Yin, T. T. Brown
Summary: This study found that people with HIV experience greater declines in muscle function and muscle mass with aging. The changes in muscle quality and quantity with aging differ between men and women with HIV and have implications on muscle function. The size and density of the psoas muscle, a key component in truncal stability and hip flexion, are associated with physical function.
JOURNAL OF FRAILTY & AGING
(2022)
Meeting Abstract
Infectious Diseases
R. J. Wang, S. M. Nouraie, K. M. Kunisaki, L. Huang, P. C. Tien, K. Anastos, N. Bhandari, S. Bhatt, H. Bolivar, S. Cribbs, R. Foronjy, S. Gange, D. Lazarous, A. Morris, MB. Drummond
Article
Multidisciplinary Sciences
Douglas M. Wallace, Maria L. Alcaide, William K. Wohlgemuth, Deborah L. Jones Weiss, Claudia Uribe Starita, Sanjay R. Patel, Valentina Stosor, Andrew Levine, Carling Skvarca, Dustin M. Long, Anna Rubtsova, Adaora A. Adimora, Stephen J. Gange, Amanda B. Spence, Kathryn Anastos, Bradley E. Aouizerat, Yaacov Anziska, Naresh M. Punjabi
Summary: The prevalence of restless legs syndrome (RLS) in men with and without HIV was similar, with HIV status not associated with RLS prevalence. White race, anemia, depression, and antidepressant use were independently associated with RLS. Men with HIV and RLS reported poorer sleep quality, greater sleepiness, and worse objective sleep efficiency/fragmentation compared to men without HIV/RLS.
