Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jin Qi, Elizabeth Kurian, Orhan K. oez
Summary: Hibernomas are rare benign tumors originating from fetal brown adipose tissue. They can occur in various parts of the body, with thigh, shoulder, back, and neck being the most common locations, and are rarely found in the abdominal cavity, retroperitoneum, breast, bones, scrotum, and perirectum. We present a case of a 58-year-old woman with a mediastinal mass, who was incidentally found to have an FDG-avid fat-containing lesion in the omentum abutting the stomach.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Oncology
Joohee Lee, Young Seok Cho, Jhingook Kim, Young Mog Shim, Kyung-Han Lee, Joon Young Choi
Summary: This study retrospectively reviewed data from 83 patients with thymic epithelial tumors who underwent pretreatment F-18-FDG PET/CT, and found that SUVavg and Masaoka stage were independent prognostic factors for progression-free survival in thymic epithelial tumors.
Article
Oncology
Sang Hyun Hwang, Minkyu Jung, Yong Hyu Jeong, KwanHyeong Jo, Soyoung Kim, Jiyoung Wang, Arthur Cho
Summary: The study evaluated the prognostic value of F-18-FDG PET/CT in localized primary GIST patients and compared its predictive values with clinicopathological factors. MTV and TLG were found to be independent prognostic factors for predicting recurrence. Patients with high MTV or TLG are at risk for poor prognosis and should be closely monitored for disease recurrence.
CANCER & METABOLISM
(2021)
Article
Oncology
Clement Bouron, Clara Mathie, Valerie Seegers, Olivier Morel, Pascal Jezequel, Hamza Lasla, Camille Guillerminet, Sylvie Girault, Marie Lacombe, Avigaelle Sher, Franck Lacoeuille, Anne Patsouris, Aude Testard
Summary: The aim of this study was to evaluate PET/CT parameters for determining different prognostic groups in triple-negative breast cancer (TNBC). The study found that MTV, TLG, and entropy could be of interest in predicting the prognostic outcome of TNBC patients. Textural features associated with metabolic and volumetric parameters of baseline [F-18]FDG PET/CT have a prognostic value for identifying high-relapse-risk groups in early TNBC patients.
Article
Oncology
Jianlin Wang, Xiaopeng Yu, Aiqi Shi, Long Xie, Liqun Huang, Yingrui Su, Jinshun Zha, Jiangyan Liu
Summary: The study aimed to investigate the predictive value of pre-treatment F-18-FDG PET/CT multi-metabolic parameters and tumor metabolic heterogeneity for gastric cancer prognosis. The results showed that a metabolic heterogeneity index called HI-1 was an independent risk factor for patient prognosis, and could be used to guide personalized treatment.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Ding, Jiangdong Qiu, Zhixin Hao, Hua Huang, Qiaofei Liu, Wenjing Liu, Chao Ren, Marcus Hacker, Taiping Zhang, Wenming Wu, Xiang Li, Li Huo
Summary: This study evaluated the performance of [(68) Ga]Ga-FAPI-04 and [F-18]F-FDG PET/CT on the disease staging and prognostic value of patients with localized PDAC. The results showed that [(68) Ga]Ga-FAPI-04 was more sensitive and accurate than [F-18]F-FDG, and could be used for staging and prognostic evaluation of PDAC, providing a non-invasive guide for clinical management.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
JingXing Xiao, Min Su, Dong Wang
Summary: Primary malignant melanoma in the oropharynx is extremely rare, with this case report detailing a 49-year-old male presenting with progressive dysphagia. After undergoing total resection of the tumor, the patient showed no signs of recurrence after a 6-month follow-up.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Pharmacology & Pharmacy
F. Aras, A. Olmezoglu
Summary: This study investigated the predictive value of quantitative metabolic tumor volume and metabolic index analysis in lung cancer stereotactic radiotherapy using F-18 FDG PET/CT. The results showed that a decrease in gross tumor volume (GTV) and pretreatment SUVmean correlated with survival. Patients with peripheral tumors had lower mortality rates and higher BED10 values.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Oncology
Wenzhi Jia, Qianyun Wu, Xiaofeng Yu, Mengqin Shen, Ruixue Zhang, Jiajin Li, Li Zhao, Gang Huang, Jianjun Liu
Summary: The glycolytic enzyme fructose 1,6-bisphosphate aldolase B (ALDOB) is inversely correlated with F-18-fluorodeoxyglucose (F-18-FDG) uptake in hepatocellular carcinoma (HCC) patients. The combination of ALDOB expression and F-18-FDG PET/CT data may provide additional prognostic information for HCC patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Jian-Wei Yang, Ling-Ling Yuan, Yan Gao, Xu-Sheng Liu, Yu-Jiao Wang, Lu-Meng Zhou, Xue-Yan Kui, Xiao-Hui Li, Chang-Bin Ke, Zhi-Jun Pei
Summary: The study found a correlation between the expression levels of EIF2S2 gene and F-18-FDG PET/CT metabolic parameters in CRC patients, and a positive correlation between EIF2S2 and GLUT1 expression. Overexpression of EIF2S2 in CRC can promote glycolysis.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Falko Ensle, Jan A. Schaab, Florentia Dimitriou, Martin W. Huellner, Alexander Maurer
Summary: We report the F-18-FDG PET/CT findings of an internal thoracic vein tumor thrombus in a 76-year-old woman with melanoma. The restaging F-18-FDG PET/CT revealed disease progression with an internal thoracic vein tumor thrombus associated with sternal bone metastasis. Although cutaneous malignant melanoma can metastasize to any organ, direct tumor invasion of veins leading to tumor thrombus formation is an extremely rare complication.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sung Ryul Shim, Seong-Jang Kim
Summary: This study evaluated the diagnostic accuracies of F-18-FDG PET or PET/CT for Merkel cell carcinoma (MCC) through a systematic review and meta-analysis. The results showed that F-18-FDG PET/CT had excellent performance in diagnosing MCC and could be useful for exclusion and confirmation of the disease. Further large multicenter studies are needed to validate its diagnostic accuracy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Oncology
Jun Liu, Yukun Si, Ziang Zhou, Xu Yang, Cuicui Li, Luodan Qian, Li Juan Feng, Mingyu Zhang, Shu Xin Zhang, Jie Liu, Ying Kan, Jianhua Gong, Jigang Yang
Summary: This study aimed to evaluate the prognostic value of intratumoral metabolic heterogeneity in primary tumor lesions of neuroblastoma (NB) patients. The results showed that intratumoral metabolic heterogeneity of primary lesions was associated with event-free survival (EFS), and patients with higher intratumoral metabolic heterogeneity and bone marrow involvement (BMI) had worse outcomes.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yun Chen, Shan Zheng, Zenan Wu, Yanmin Lin, Weibing Miao
Summary: A 76-year-old man with yellowish discoloration of sclera and skin for 2 months was referred for F-18-FDG PET/CT to characterize a mass in the pancreas. PET/CT images showed intense FDG uptake in the head of the pancreas, with a lymph nodal mass in the hepatic hilar region, consistent with pancreatic malignancy. Histopathologic findings confirmed diffuse large B-cell lymphoma with no evidence of adenocarcinoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Medicine, General & Internal
Ricarda Hinzpeter, Seyed Ali Mirshahvalad, Roshini Kulanthaivelu, Vanessa Murad, Claudia Ortega, Ur Metser, Zhihui Amy Liu, Elena Elimova, Rebecca K. S. Wong, Jonathan Yeung, Raymond W. Jang, Patrick Veit-Haibach
Summary: We investigated the prognostic value of sarcopenia measurements and metabolic parameters derived from F-18-FDG-PET/CT in patients with esophageal and gastroesophageal cancer. The results showed that sarcopenia status was significantly associated with survival prognosis, while standard metabolic parameters did not show significant correlation. Therefore, the combination of clinical parameters and sarcopenia status is a more effective indicator for predicting survival prognosis in patients with advanced gastroesophageal cancer.