Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 53, Issue 12, Pages 1825-1828Publisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.112.106146
Keywords
in vivo imaging; tracking; cellular therapy; transplantation; regenerative medicine
Funding
- Netherlands Institute of Regenerative Medicine (NIRM) [FES0908]
- EU [ENCITE HEALTH-F5-2008-201842]
- Netherlands Organization for Scientific Research [VENI 700.10.409, Vidi 917.76.363]
- ERC [269019]
- Radboud University Nijmegen Medical Centre [AGIKO-2008-2-4]
- [RO1 NS045062]
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Cellular therapy can be defined as the transplantation of living cells for the treatment of medical conditions. Three main objectives of cellular therapy are regeneration of damaged tissue, replacement of function by secretion of biologically active molecules, and redirection of aberrant processes. Given the complex nature of these approaches, in vivo tracking of the transplanted cells is critical to evaluate their potential benefit and to optimize treatment strategies. Recent advances are reviewed that enable in vivo cell tracking as an important adjunct to implement cellular therapy in clinical practice.
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