4.7 Article

Advances in Preclinical SPECT Instrumentation

Journal

JOURNAL OF NUCLEAR MEDICINE
Volume 53, Issue 6, Pages 841-844

Publisher

SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.111.099853

Keywords

SPECT; preclinical imaging; semiconductor detectors; multi-pinhole collimation; synthetic collimator

Funding

  1. NIH [R33EB00776, R01EB013677, K99EB009106]
  2. Department of Energy [DE-SC0002437]

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Preclinical SPECT of rodents is both in demand and very demanding. The need for high spatial resolution in combination with good sensitivity has given rise to considerable innovation in the areas of detectors, collimation, acquisition geometry, and image reconstruction. Some of the developments described herein are beginning to carry over into clinical imaging as well.

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