Biophysics of α-synuclein induced membrane remodelling

Membrane tension and peripheral protein density mediate membrane shape transitions

(2015) Zheng Shi et al.   Nature Communications

Dynamics and instabilities of lipid bilayer membrane shapes

(2014) Zheng Shi et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Protein-Induced Membrane Curvature Alters Local Membrane Tension

(2014) Padmini Rangamani et al.   BIOPHYSICAL JOURNAL

Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis

(2014) K. J. Vargas et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein-Induced Membrane Remodeling Is Driven by Binding Affinity, Partition Depth, and Interleaflet Order Asymmetry

(2014) Anthony R. Braun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mutations in BIN1 Associated with Centronuclear Myopathy Disrupt Membrane Remodeling by Affecting Protein Density and Oligomerization

(2014) Tingting Wu et al.   PLoS One

Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins

(2014) M. Pinot et al.   SCIENCE

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

α-Synuclein Can Inhibit SNARE-Mediated Vesicle Fusion through Direct Interactions with Lipid Bilayers

(2013) David C. DeWitt et al.   BIOCHEMISTRY

Kinetics of Endophilin N-BAR Domain Dimerization and Membrane Interactions

(2013) Benjamin R. Capraro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling

(2013) Myriam M. Ouberai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solid-State 13C NMR Reveals Annealing of Raft-Like Membranes Containing Cholesterol by the Intrinsically Disordered Protein α-Synuclein

(2013) Avigdor Leftin et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane Remodeling by α-Synuclein and Effects on Amyloid Formation

(2013) Zhiping Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Large  -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

(2013) B.-K. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

(2013) Jiajie Diao et al.   eLife

Monomeric Synucleins Generate Membrane Curvature

(2012) Christopher H. Westphal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Remodeling of Lipid Vesicles into Cylindrical Micelles by α-Synuclein in an Extended α-Helical Conformation

(2012) Naoko Mizuno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein Induces Both Positive Mean Curvature and Negative Gaussian Curvature in Membranes

(2012) Anthony R. Braun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-terminal acetylation is critical for forming α-helical oligomer of α-synuclein

(2012) Adam J. Trexler et al.   PROTEIN SCIENCE

α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding

(2011) Iwona M. Pranke et al.   JOURNAL OF CELL BIOLOGY

Nature of curvature coupling of amphiphysin with membranes depends on its bound density

(2011) B. Sorre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Curvature and Composition on α-Synuclein Binding to Lipid Vesicles

(2010) Elizabeth R. Middleton et al.   BIOPHYSICAL JOURNAL

Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein

(2010) Marta Robotta et al.   CHEMPHYSCHEM

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

(2010) Jobin Varkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curvature Sensing by the Epsin N-Terminal Homology Domain Measured on Cylindrical Lipid Membrane Tethers

(2010) Benjamin R. Capraro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic sorting of lipids and proteins in membrane tubes with a moving phase boundary

(2010) M. Heinrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

α-Synuclein Binds Large Unilamellar Vesicles as an Extended Helix†

(2009) Adam J. Trexler et al.   BIOCHEMISTRY

Flip-Flop-Induced Relaxation of Bending Energy: Implications for Membrane Remodeling

(2009) R.J. Bruckner et al.   BIOPHYSICAL JOURNAL

Sorting of Lipids and Proteins in Membrane Curvature Gradients

(2009) A. Tian et al.   BIOPHYSICAL JOURNAL

Measurement of the membrane curvature preference of phospholipids reveals only weak coupling between lipid shape and leaflet curvature

(2009) Marzuk M. Kamal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trans-monolayer coupling of fluid domains in lipid bilayers

(2009) Sylvio May   Soft Matter

Membrane-Thinning Effect of Curcumin

(2008) Wei-Chin Hung et al.   BIOPHYSICAL JOURNAL

The Bound States of Amphipathic Drugs in Lipid Bilayers: Study of Curcumin

(2008) Yen Sun et al.   BIOPHYSICAL JOURNAL

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY