JC polyomavirus attachment, entry, and trafficking: unlocking the keys to a fatal infection

Identification of a Novel Polyomavirus in a Pancreatic Transplant Recipient With Retinal Blindness and Vasculitic Myopathy

(2014) Nischay Mishra et al.   JOURNAL OF INFECTIOUS DISEASES

The human polyomaviruses: from orphans and mutants to patchwork family

(2013) Christine Hanssen Rinaldo et al.   APMIS

N-Methyldihydroquinazolinone Derivatives of Retro-2 with Enhanced Efficacy against Shiga Toxin

(2013) Romain Noel et al.   JOURNAL OF MEDICINAL CHEMISTRY

5-HT2 Receptors Facilitate JC Polyomavirus Entry

(2013) B. Assetta et al.   JOURNAL OF VIROLOGY

A cornucopia of human polyomaviruses

(2013) James A. DeCaprio et al.   NATURE REVIEWS MICROBIOLOGY

Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus

(2013) A. Lipovsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome

(2013) Emmanuelle Girard et al.   TRAFFIC

A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses

(2013) C. D. S. Nelson et al.   mBio

Progressive Multifocal Leukoencephalopathy-Associated Mutations in the JC Polyomavirus Capsid Disrupt Lactoseries Tetrasaccharide c Binding

(2013) M. S. Maginnis et al.   mBio

A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus

(2013) Ursula Neu et al.   PLoS Pathogens

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

(2012) M. W. Ferenczy et al.   CLINICAL MICROBIOLOGY REVIEWS

Update on Progressive Multifocal Leukoencephalopathy

(2012) Israel Steiner et al.   Current Neurology and Neuroscience Reports

Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

(2012) Gary Bloomgren et al.   NEW ENGLAND JOURNAL OF MEDICINE

The relationship between the plasma concentration of blonanserin, and its plasma anti-serotonin 5-HT2A activity/anti-dopamine D2 activity ratio and drug-induced extrapyramidal symptoms

(2012) Hidenobu Suzuki et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry

(2012) Christian D.S. Nelson et al.   VIROLOGY

Inhibitors of the Cellular Trafficking of Ricin

(2012) Julien Barbier et al.   Toxins

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

The cell biology of receptor-mediated virus entry

(2011) Joe Grove et al.   JOURNAL OF CELL BIOLOGY

Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients

(2011) Carl E. Reid et al.   JOURNAL OF INFECTIOUS DISEASES

Progressive Multifocal Leukoencephalopathy (PML) Development Is Associated With Mutations in JC Virus Capsid Protein VP1 That Change Its Receptor Specificity

(2011) Leonid Gorelik et al.   JOURNAL OF INFECTIOUS DISEASES

Progressive multifocal leukoencephalopathy and natalizumab

(2011) Kerstin Hellwig et al.   JOURNAL OF NEUROLOGY

Frequent Infection of Cortical Neurons by JC Virus in Patients With Progressive Multifocal Leukoencephalopathy

(2011) Christian Wüthrich et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Role of Endosomes in Simian Virus 40 Entry and Infection

(2011) S. Engel et al.   JOURNAL OF VIROLOGY

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

(2011) Roger Geiger et al.   NATURE CELL BIOLOGY

Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases

(2011) Stefanie A. Krumm et al.   PLoS One

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)

(2011) A. Bonavia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge

(2010) Bahne Stechmann et al.   CELL

Structure-Function Analysis of the Human JC Polyomavirus Establishes the LSTc Pentasaccharide as a Functional Receptor Motif

(2010) Ursula Neu et al.   Cell Host & Microbe

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

(2010) Arnold Hayer et al.   JOURNAL OF CELL BIOLOGY

Human Polyomavirus JC (JCV) Infection of Human B Lymphocytes: A Possible Mechanism for JCV Transmigration across the Blood‐Brain Barrier

(2010) Moti L. Chapagain et al.   JOURNAL OF INFECTIOUS DISEASES

Lipids and Proteins Act in Opposing Manners To Regulate Polyomavirus Infection

(2010) M. Qian et al.   JOURNAL OF VIROLOGY

A PDI Family Network Acts Distinctly and Coordinately with ERp29 To Facilitate Polyomavirus Infection

(2010) C. P. Walczak et al.   JOURNAL OF VIROLOGY

Role of N-Linked Glycosylation of the 5-HT2A Receptor in JC Virus Infection

(2010) M. S. Maginnis et al.   JOURNAL OF VIROLOGY

Progressive multifocal leukoencephalopathy and other forms of JC virus disease

(2010) Bruce J. Brew et al.   Nature Reviews Neurology

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Prevalence of Polyomavirus BK and JC Infection and Replication in 400 Healthy Blood Donors

(2009) Adrian Egli et al.   JOURNAL OF INFECTIOUS DISEASES

Distinct Glycan Topology for Avian and Human Sialopentasaccharide Receptor Analogues upon Binding Different Hemagglutinins: A Molecular Dynamics Perspective

(2009) Dong Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project

(2009) Kenneth R Carson et al.   LANCET ONCOLOGY

GM1 structure determines SV40-induced membrane invagination and infection

(2009) Helge Ewers et al.   NATURE CELL BIOLOGY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Polyomaviridae: Contributions of virus structure to our understanding of virus receptors and infectious entry

(2009) Ursula Neu et al.   VIROLOGY

Adaptive Mutations in the JC Virus Protein Capsid Are Associated with Progressive Multifocal Leukoencephalopathy (PML)

(2009) Shamil R. Sunyaev et al.   PLoS Genetics

A Lipid Receptor Sorts Polyomavirus from the Endolysosome to the Endoplasmic Reticulum to Cause Infection

(2009) Mengding Qian et al.   PLoS Pathogens

Astrocytes, but not olfactory ensheathing cells or Schwann cells, promote myelination of CNS axonsin vitro

(2008) Annette Sorensen et al.   GLIA

Sialic acid moieties and 5-HT2a: Two faces of the same receptor for JC virus ?

(2008) Daniele Focosi et al.   JOURNAL OF CLINICAL VIROLOGY

Frequent Infection of Cerebellar Granule Cell Neurons by Polyomavirus JC in Progressive Multifocal Leukoencephalopathy

(2008) Christian Wüthrich et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

JC virus VP1 loop-specific polymorphisms are associated with favorable prognosis for progressive multifocal leukoencephalopathy

(2008) Serena Delbue et al.   JOURNAL OF NEUROVIROLOGY

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cells Express the Serotonin Receptor and Are Susceptible to JC Virus Infection

(2008) C. Schaumburg et al.   JOURNAL OF VIROLOGY

Structural basis of GM1 ganglioside recognition by simian virus 40

(2008) Ursula Neu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

(2008) H. Feng et al.   SCIENCE

Transcriptional control region rearrangements associated with the evolution of JC polyomavirus

(2008) Yoshiaki Yogo et al.   VIROLOGY

Interferon β1-a and selective anti-5HT2a receptor antagonists inhibit infection of human glial cells by JC virus

(2008) B.A. O’Hara et al.   VIRUS RESEARCH