Post-Injury Delivery of rAAV2-CNTF Combined with Short-Term Pharmacotherapy Is Neuroprotective and Promotes Extensive Axonal Regeneration after Optic Nerve Trauma

Retinal Ganglion Cell Gene Therapy and Visual System Repair

(2011) Mats Hellstrom et al.   CURRENT GENE THERAPY

Effect of Neurotrophin-3 Genetically Modified Olfactory Ensheathing Cells Transplantation on Spinal Cord Injury

(2010) Yu-Hai Ma et al.   CELL TRANSPLANTATION

Complications of intravitreal injections

(2010) Kapil M Sampat et al.   CURRENT OPINION IN OPHTHALMOLOGY

Are the neurotrophic factors a suitable therapeutic target for the prevention of epileptogenesis?

(2010) Michele Simonato et al.   EPILEPSIA

Self-complementary AAV5 vector facilitates quicker transgene expression in photoreceptor and retinal pigment epithelial cells of normal mouse

(2010) Fansheng Kong et al.   EXPERIMENTAL EYE RESEARCH

Mechanisms of retinal ganglion cell injury and defense in glaucoma

(2010) Juan Qu et al.   EXPERIMENTAL EYE RESEARCH

Widespread cortical expression of MANF by AAV serotype 7: Localization and protection against ischemic brain injury

(2010) Mikko Airavaara et al.   EXPERIMENTAL NEUROLOGY

Progress and prospects: stem cells and neurological diseases

(2010) S Gögel et al.   GENE THERAPY

Long-Distance Axon Regeneration in the Mature Optic Nerve: Contributions of Oncomodulin, cAMP, and pten Gene Deletion

(2010) T. Kurimoto et al.   JOURNAL OF NEUROSCIENCE

Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons

(2010) M. Hellström et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons

(2010) Matthew RJ Mason et al.   MOLECULAR THERAPY

Gene therapy for Parkinson's disease

(2010) Tomas Bjorklund et al.   MOVEMENT DISORDERS

Gene Therapy for Neurological Disorders: Challenges and Future Prospects for the Use of Growth Factors for the Treatment of Parkinsons Disease

(2009) Fredric Manfredsson et al.   CURRENT GENE THERAPY

Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors

(2009) A A Rahim et al.   GENE THERAPY

Postischemic IGF-1 Gene Transfer Promotes Neurovascular Regeneration after Experimental Stroke

(2009) Wei Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS

(2009) Sandra R. Alcalá-Barraza et al.   JOURNAL OF DRUG TARGETING

Neuroprotective and Axon Growth-Promoting Effects following Inflammatory Stimulation on Mature Retinal Ganglion Cells in Mice Depend on Ciliary Neurotrophic Factor and Leukemia Inhibitory Factor

(2009) M. Leibinger et al.   JOURNAL OF NEUROSCIENCE

Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors

(2009) Bas Blits et al.   JOURNAL OF NEUROSCIENCE METHODS

Early Events of Secondary Degeneration after Partial Optic Nerve Transection: An Immunohistochemical Study

(2009) Melinda Fitzgerald et al.   JOURNAL OF NEUROTRAUMA

Cytokine-induced SOCS expression is inhibited by cAMP analogue: Impact on regeneration in injured retina

(2009) Kevin K. Park et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Exogenous CNTF stimulates axon regeneration of retinal ganglion cells partially via endogenous CNTF

(2009) Adrienne Müller et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cell Therapy for CNS Trauma

(2009) K. K. Jain   MOLECULAR BIOTECHNOLOGY

Ex Vivo VEGF Delivery by Neural Stem Cells Enhances Proliferation of Glial Progenitors, Angiogenesis, and Tissue Sparing after Spinal Cord Injury

(2009) Hyuk Min Kim et al.   PLoS One

Oncomodulin links inflammation to optic nerve regeneration

(2009) Y. Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity

(2008) Véronique Planchamp et al.   BRAIN

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

(2008) M Hellström et al.   GENE THERAPY

Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice

(2008) Mariacarmela Allocca et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel AAV serotypes for improved ocular gene transfer

(2008) Corinna Lebherz et al.   JOURNAL OF GENE MEDICINE

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY

The role of macrophages in optic nerve regeneration

(2008) Q. Cui et al.   NEUROSCIENCE

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin Growth Factor-1 Gene Transfer Enhances Neurovascular Remodeling and Improves Long-Term Stroke Outcome in Mice

(2008) Wei Zhu et al.   STROKE

Growth factors and combinatorial therapies for CNS regeneration

(2007) Paul Lu et al.   EXPERIMENTAL NEUROLOGY

Rewiring the injured CNS: Lessons from the optic nerve

(2007) Larry Benowitz et al.   EXPERIMENTAL NEUROLOGY