Article
Anesthesiology
Miho Shibamura-Fujiogi, Jennifer Ormsby, Mark Breibart, Benjamin Warf, Gregory P. Priebe, Sulpicio G. Soriano, Thomas J. Sandora, Koichi Yuki
Summary: This retrospective cohort study identified that receiving clindamycin as perioperative prophylaxis and having cardiac disease were significantly associated with surgical site infections (SSIs) in shunt procedures. Cefazolin is recommended as a standard antibiotic for perioperative prophylaxis, and further research is needed to understand the mechanism by which cardiac disease may increase SSI risk after shunt procedures.
BMC ANESTHESIOLOGY
(2021)
Article
Neurosciences
Min Li Tey, Lee Ping Ng, David C. Y. Low, Wan Tew Seow, Sharon Y. Y. Low
Summary: This study evaluates the efficacy of programmable shunt valves (PSV) as a treatment modality for pediatric hydrocephalus. Results show that the mean number of adjustments per PSV is 1.82 times, with MEDTRONIC(TM) Strata PSVs having significantly lower adjustment rates compared to others.
Review
Clinical Neurology
Cezar Octavian Morosanu, Adelina Priscu, Razvan George Rahota, Ioan Stefan Florian
Summary: Hydrocephalus is a pathological condition that can greatly affect the quality of life. Cerebrospinal fluid diversions to the renal system are an alternative treatment option with advantages, but also have potential issues that require further research for proper evaluation in current practice.
CHILDS NERVOUS SYSTEM
(2023)
Review
Clinical Neurology
Anant Naik, Natalie Ramsy, David T. Krist, Birra Taha, Rajiv Dharnipragada, Rukhsaar Khanam, Carolina Sandoval-Garcia, Wael Hassaneen, Elizabeth C. Tyler-Kabara, Paul M. Arnold
Summary: This study systematically reviewed clinical studies on anterior and posterior ventriculoperitoneal shunt placement and performed a meta-analysis. The results showed that anterior and posterior shunts had mostly comparable outcomes, but anteriorly placed shunts had better survival rates at 2-year and 5-year intervals.
WORLD NEUROSURGERY
(2022)
Review
Clinical Neurology
Jennifer Deger, Eric A. Goethe, Melissa A. LoPresti, Sandi Lam
Summary: Intraventricular hemorrhage (IVH) is a common neurosurgical disease in premature infants, and despite significant advances in treatment over time, it continues to impact patient and caregiver quality of life and healthcare costs. The evolution of management for IVH has transitioned from medical to surgical interventions, with a focus on correcting coagulopathy and addressing factors contributing to perinatal instability. IVH remains a significant cause of morbidity and mortality in premature infants, highlighting the importance of understanding past approaches in developing new treatments.
WORLD NEUROSURGERY
(2021)
Review
Clinical Neurology
Cezar Octavian Morosanu, Adelina Priscu, Ioan Stefan Florian
Summary: This review summarizes the currently available information on using the gallbladder as a viable option for cerebrospinal fluid diversion, and also mentions other therapeutic options in the context of hydrocephalus.
NEUROSURGICAL REVIEW
(2021)
Article
Clinical Neurology
Sandeep Muram, Albert M. Isaacs, Nicholas Sader, Richard Holubkov, Annie Fong, John Conly, Mark G. Hamilton
Summary: This study aimed to create a standardized infection prevention bundle to reduce the rate of shunt infections. The implementation of Calgary Adult Shunt Infection Prevention Protocol (CASIPP) significantly reduced the infection rate, and the introduction of chlorhexidine/alcohol further decreased the rate to 0%. Multivariable logistic regression analysis showed that the use of chlorhexidine/alcohol with CASIPP was associated with a significant reduction in the odds of developing a shunt infection.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Syed I. I. Khalid, Brittany M. M. Hunter, Pal Shah, Aashka Patel, Kyle B. B. Thomson, Melissa A. A. LoPresti, Douglas W. W. Roblin, Sandi Lam, Ankit I. I. Mehta
Summary: Social risk factors have a negative impact on health outcomes in pediatric shunted hydrocephalus, leading to increased rates of infection, revision, and mortality. Interventions targeting these risk factors are necessary to improve the outcomes of children undergoing CSF diversion.
Review
Neurosciences
Yi-Jen Ho, Wen-Chun Chiang, Hsin-Yi Huang, Shinn-Zong Lin, Sheng-Tzung Tsai
Summary: This meta-analysis evaluates the safety and effectiveness of lumboperitoneal shunt (LPS) compared to ventriculoperitoneal shunt (VPS) for treating communicating hydrocephalus. The results show that LPS has lower complication and obstruction rates, and improves radiological outcomes.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Clinical Neurology
Hengameh B. Pajer, Andrew P. Carlson, James A. Botros, Heather S. Spader
Summary: This study found that Apple Watch interferes with the normal operation of the Codman CERTAS Plus electronic programmer, and keeping Apple Watch away from the programmer can prevent incorrect readings and setting changes.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Hengameh B. Pajer, Andrew P. Carlson, James A. Botros, Heather S. Spader
Summary: The study found that Apple Watches emit significant magnetic fields which interfere with the Codman CERTAS Plus electronic programmer, causing difficulties in valve programming. This highlights the importance of keeping smartwatches and other electronic devices away from the programmer to avoid incorrect readings and setting changes.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Wilson A. M. Fisher, Michael P. Catalino, E. Alice Woolard, Bethany J. Andrews, Scott Elton, Carolyn Quinsey
Summary: This study explored the impact of surgical techniques and instruments on the mechanical integrity of ventriculoperitoneal shunt system, specifically shunt catheters. The results showed that the failure rates varied significantly depending on the instruments used and the assembly technique. The use of mosquito forceps with shods and technique A resulted in significantly lower failure rates, while DeBakey forceps were found to be the most damaging instrument.
JOURNAL OF NEUROSURGERY
(2023)
Article
Behavioral Sciences
Nadia Mansoor, Ole Solheim, Oddrun A. Fredriksli, Sasha Gulati
Summary: Shunt surgery in children is associated with high revision and complication rates. Misplacement of hardware and proximal occlusion were the most common reasons for revision surgery. It is important to focus on reducing misplacement and addressing other complications within 30 days postoperatively.
BRAIN AND BEHAVIOR
(2021)
Article
Clinical Neurology
V. Tcherbbis Testa, S. Jaimovich, R. Arganaraz, B. Mantese
Summary: Understanding the mechanisms of increased intracranial pressure and the role of cerebrospinal fluid is crucial in managing pediatric patients with syndromic craniosynostosis. Among 33 patients requiring craniofacial surgery, more than half developed ventriculomegaly and nearly 40% needed ventriculoperitoneal shunt placement.
ACTA NEUROCHIRURGICA
(2021)
Article
Biology
Fatemeh Khodadadei, Allen P. Liu, Carolyn A. Harris
Summary: The study suggests that shear forces in hydrocephalus shunts lead to increased cytokine secretion by astrocytes, contributing to shunt failure. Real-time imaging confirmed the importance of reducing shear stress activation of cells to prevent shunt failure.
COMMUNICATIONS BIOLOGY
(2021)
Article
Clinical Neurology
Charlotte Dandurand, Cristina Schaurich, Mandeep Tamber, Patrick McDonald, Paul Steinbok
Summary: This study reviewed the outcomes of pediatric intracranial infection management with immediate replacement of the bone flap in a Canadian center, showing that this approach is reasonable and can reduce the risk of recurrent infection.
CHILDS NERVOUS SYSTEM
(2021)
Article
Medicine, Research & Experimental
Marie T. Kruger, Josue M. Avecillas-Chasin, Mandeep S. Tamber, Manraj K. S. Heran, Mini K. Sandhu, Nancy E. Polyhronopoulos, Natasha Sarai, Christopher R. Honey
Summary: This study compared the ability of standard and directional deep brain stimulation systems to reduce tremor without side-effects and improve quality of life for patients with advanced essential tremor. The results showed a significantly greater reduction in tremor without side-effects when using the directional system, as well as improvements in tremor and voice related quality of life compared to the standard system. The findings suggest that replacing deep brain stimulation with a directional system can significantly improve tremor and quality of life in advanced essential tremor patients who no longer respond well to standard treatments.
Article
Clinical Neurology
Patricia Mortenson, Nishanth Sadashiva, Mandeep S. Tamber, Paul Steinbok
Summary: The study found that improvements in upper extremity function following SDR surgery can be sustained in the long term, indicating long-term benefits of SDR surgery for upper limb function.
CHILDS NERVOUS SYSTEM
(2021)
Article
Clinical Neurology
Mandeep S. Tamber, John R. W. Kestle, Ron W. Reeder, Richard Holubkov, Jessica Alvey, Samuel R. Browd, James M. Drake, Abhaya Kulkarni, David D. Limbrick, Patrick J. McDonald, Curtis J. Rozzelle, Tamara D. Simon, Robert Naftel, Chevis N. Shannon, John C. Wellons, William E. Whitehead, Jay Riva-Cambrin
Summary: The study analyzed trends in patient characteristics and surgical management of pediatric hydrocephalus over a 9-year period by using data from 9 centers. It found a decrease in new shunt insertions and an increase in new ETV procedures over time, as well as a significant decrease in revision procedures. This suggests an improvement in the quality of surgical care for pediatric hydrocephalus.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Article
Clinical Neurology
Jason S. Hauptman, John Kestle, Jay Riva-Cambrin, Abhaya Kulkarni, Samuel R. Browd, Curtis J. Rozzelle, William E. Whitehead, Robert P. Naftel, Jonathan Pindrik, David D. Limbrick, James Drake, John C. Wellons, Mandeep S. Tamber, Chevis N. Shannon, Tamara D. Simon, Ian F. Pollack, Patrick J. McDonald, Mark D. Krieger, Jason Chu, Todd C. Hankinson, Eric M. Jackson, Jessica S. Alvey, Ron W. Reeder, Richard Holubkov
Summary: The study revealed that the etiology of hydrocephalus and previous failure history are associated with fast shunt failure, while age at the time of procedure and hydrocephalus etiology are linked to ultrafast failure.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Article
Clinical Neurology
Travis S. CreveCoeur, Alexander T. Yahanda, Cormac O. Maher, Gabrielle W. Johnson, Laurie L. Ackerman, P. David Adelson, Raheel Ahmed, Gregory W. Albert, Phillipp R. Aldana, Tord D. Alden, Richard C. E. Anderson, Lissa Baird, David F. Bauer, Karin S. Bierbrauer, Douglas L. Brockmeyer, Joshua J. Chern, Daniel E. Couture, David J. Daniels, Robert C. Dauser, Susan R. Durham, Richard G. Ellenbogen, Ramin Eskandari, Herbert E. Fuchs, Timothy M. George, Gerald A. Grant, Patrick C. Graupman, Stephanie Greene, Jeffrey P. Greenfield, Naina L. Gross, Daniel J. Guillaume, Gabe Haller, Todd C. Hankinson, Gregory G. Heuer, Mark Iantosca, Bermans J. Iskandar, Eric M. Jackson, Andrew H. Jea, James M. Johnston, Robert F. Keating, Michael P. Kelly, Nickalus Khan, Mark D. Krieger, Jeffrey R. Leonard, Francesco T. Mangano, Timothy B. Mapstone, J. Gordon McComb, Arnold H. Menezes, Michael Muhlbauer, W. Jerry Oakes, Greg Olavarria, Brent R. O'Neill, Tae Sung Park, John Ragheb, Nathan R. Selden, Manish N. Shah, Chevis Shannon, Joshua S. Shimony, Jodi Smith, Matthew D. Smyth, Scellig S. D. Stone, Jennifer M. Strahle, Mandeep S. Tamber, James C. Torner, Gerald F. Tuite, Scott D. Wait, John C. Wellons, William E. Whitehead, David D. Limbrick
Summary: The study examined factors influencing the use of occipital-cervical fusion (OCF) and ventral decompression (VD) in pediatric Chiari-1 malformation (CM-1) patients with syringomyelia (SM) undergoing posterior fossa decompression (PFD). While the majority of patients were treated with PFD alone, a small number required OCF or OCF/VD, with cranial base and spine pathologies influencing the need for these additional surgeries.
Article
Clinical Neurology
Andrew T. Hale, Jay Riva-Cambrin, John C. Wellons, Eric M. Jackson, John R. W. Kestle, Robert P. Naftel, Todd C. Hankinson, Chevis N. Shannon
Summary: Machine learning approaches, particularly the artificial neural network (ANN), show promise in accurately predicting CSF shunt failure and can potentially assist in personalized patient counseling post-shunt placement.
CHILDS NERVOUS SYSTEM
(2021)
Article
Multidisciplinary Sciences
David D. Limbrick, Diego M. Morales, Chevis N. Shannon, John C. Wellons, Abhaya Kulkarni, Jessica S. Alvey, Ron W. Reeder, Volker Freimann, Richard Holubkov, Jay K. Riva-Cambrin, William E. Whitehead, Curtis J. Rozzelle, Mandeep Tamber, W. Jerry Oakes, James M. Drake, Ian F. Pollack, Robert P. Naftel, Terrie E. Inder, John R. Kestle
Summary: The study showed that there is an association between CSF NCAM-1 and Bayley-III motor scores, indicating a potential link between NCAM-1 and neurological disability related to PHH.
Article
Clinical Neurology
Mandeep S. Tamber
Summary: Infant hydrocephalus has variable etiologies and disease burden depending on geographic region and socioeconomic status. Improved survival rates from timely diagnosis and treatment may lead to an increasing burden of hydrocephalus. Further analysis of registry-based data is needed to clarify these complex issues.
CHILDS NERVOUS SYSTEM
(2021)
Letter
Clinical Neurology
David F. Bauer, Lissa C. Baird, Ann Marie Flannery, Paul Klimo, Mandeep S. Tamber, Dimitrios C. Nikas, Catherine A. Mazzola, Patricia Rehring
Article
Clinical Neurology
Jay Riva-Cambrin, Abhaya Kulkarni, Robert Burr, Curtis J. Rozzelle, W. Jerry Oakes, James M. Drake, Jessica S. Alvey, Ron W. Reeder, Richard Holubkov, Samuel R. Browd, D. Douglas Cochrane, David D. Limbrick, Robert Naftel, Chevis N. Shannon, Tamara D. Simon, Mandeep S. Tamber, Patrick J. McDonald, John C. Wellons, Thomas G. Luerssen, William E. Whitehead, John R. W. Kestle
Summary: In this comprehensive, multicenter study that included children with heterogeneous hydrocephalus etiologies, minimal associations were found between treated ventricle size and neuropsychological, academic, or quality-of-life outcomes for pediatric patients.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
William E. Whitehead, Jay Riva-Cambrin, John C. Wellons, Abhaya Kulkarni, David D. Limbrick, Vanessa L. Wall, Curtis J. Rozzelle, Todd C. Hankinson, Patrick J. McDonald, Mark D. Krieger, Ian F. Pollack, Mandeep S. Tamber, Jonathan Pindrik, Jason S. Hauptman, Robert P. Naftel, Chevis N. Shannon, Jason Chu, Eric M. Jackson, Samuel R. Browd, Tamara D. Simon, Richard Holubkov, Ron W. Reeder, Hailey Jensen, Jenna E. Koschnitzky, Paul Gross, James M. Drake, John R. W. Kestle
Summary: This study comparing the anterior and posterior shunt entry sites found no significant difference in the time to shunt failure. The outcomes and complication rates were similar for both entry sites.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
Jason Chu, Hailey Jensen, Richard Holubkov, Mark D. Krieger, Abhaya V. Kulkarni, Jay Riva-Cambrin, Curtis J. Rozzelle, David D. Limbrick, John C. Wellons, Samuel R. Browd, William E. Whitehead, Ian F. Pollack, Tamara D. Simon, Mandeep S. Tamber, Jason S. Hauptman, Jonathan Pindrik, Robert P. Naftel, Patrick J. McDonald, Todd C. Hankinson, Eric M. Jackson, Brandon G. Rocque, Ron Reeder, James M. Drake, John R. W. Kestle
Summary: This study evaluated the compliance with a simplified protocol for shunt procedures and assessed modifiable risk factors for shunt infection. The results showed high compliance with the protocol and identified the use of antibiotic-impregnated catheters and vancomycin irrigation as protective factors against infection.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Article
Clinical Neurology
Brandon G. Rocque, Hailey Jensen, Ron W. Reeder, Abhaya V. Kulkarni, Ian F. Pollack, John C. Wellons III, Robert P. Naftel, Eric M. Jackson, William E. Whitehead, Jonathan A. Pindrik, David D. Limbrick Jr, Patrick J. McDonald, Mandeep S. Tamber, Todd C. Hankinson, Jason S. Hauptman, Mark D. Krieger, Jason Chu, Tamara D. Simon, Jay Riva-Cambrin, John R. W. Kestle, Curtis J. Rozzelle
Summary: This study aimed to evaluate the success rate of postshunt endoscopic third ventriculostomy (ETV) for hydrocephalus treatment. Only the surgeon's report of a clear view of the basilar artery was significantly associated with success, while factors such as age and etiology of hydrocephalus did not affect the success rate. The overall complication rate was 22%, with CSF leak being the most common.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2022)
Letter
Medicine, General & Internal
Paul Steinbok, Alexander Cheong, David B. Dix, Sanjiv Bhatia, Michael H. Handler, David D. Limbrick, Toba Niazi, Angela V. Price, John Ragheb, Mark Souweidane, Mandeep S. Tamber, David I. Sandberg
NEW ENGLAND JOURNAL OF MEDICINE
(2022)