Article
Clinical Neurology
Konstantin L. Makridis, Christine Prager, Anna Tietze, Deniz A. Atalay, Sebastian Triller, Christian E. Elger, Ulrich-Wilhelm Thomale, Angela M. Kaindl
Summary: In an infant at the corrected age of 1 week, hemispherotomy for drug-resistant epilepsy was successful, with no complications during the surgery and the patient has been seizure-free since discharge. Early epilepsy surgery in very young infants can be safe and effective if performed in a specialized center experienced with age-specific conditions.
FRONTIERS IN NEUROLOGY
(2021)
Article
Pharmacology & Pharmacy
Ting Zhang, Hua Feng, Wei Xiao, Jingsheng Li, Qinghai Liu, Xuexin Feng, Dezhou Qi, Xiaotong Fan, Yongzhi Shan, Tao Yu, Guoguang Zhao, Tianlong Wang
Summary: Prophylactic administration of TXA combined with TEG-guided hemostatic algorithm can be an effective multimodal coagulation strategy for reducing allogeneic transfusion requirements during pediatric resective epilepsy surgery.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Orthopedics
Steven B. Porter, Aaron C. Spaulding, Christopher M. Duncan, Benjamin K. Wilke, Mark W. Pagnano, Matthew P. Abdel
Summary: In high-risk patients with hip fracture requiring arthroplasty, the administration of tranexamic acid (TXA) was not associated with an increased risk of thrombotic complications or mortality within 90 days.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Dentistry, Oral Surgery & Medicine
Michael Schwaiger, Juergen Wallner, Sarah-Jayne Edmondson, Irene Mischak, Jasmin Rabensteiner, Thomas Gary, Wolfgang Zemann
Summary: This prospective observational study aimed to investigate the parameter of hidden blood loss in orthognathic surgery to improve patient safety and postoperative outcomes. Significant differences in bleeding volumes and hidden blood loss were found between the bimaxillary surgery group and the Bilateral Sagittal Split Osteotomy group.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2021)
Article
Medicine, Research & Experimental
Chenyu Jin, Xiang Lv, Yu Sun, Hong Jiang
Summary: Dexmedetomidine can decrease blood loss in orthognathic surgery, reduce surgical risks, and increase postoperative hemoglobin levels for patients.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2021)
Article
Medicine, General & Internal
Shu Li, Xiang Yan, Ruowen Li, Xingyue Zhang, Tingting Ma, Min Zeng, Jia Dong, Juan Wang, Xiaoyuan Liu, Yuming Peng
Summary: This article describes a non-inferiority trial to evaluate the use of the antifibrinolytic agent tranexamic acid (TXA) in neurosurgical procedures. The study aims to assess the impact of TXA on early postoperative seizures and other related outcomes.
Article
Multidisciplinary Sciences
Hidenobu Sakuma, Daichi Hasebe, Ryoko Takeuchi, Taichi Hara, Daisuke Suda, Naoaki Saito, Daisuke Saito, Tadaharu Kobayashi
Summary: This study compared the use of a powered instrument and ultrasonic curettage device in orthognathic surgery and found that using the ultrasonic device significantly reduced intraoperative blood loss and calculated blood loss.
Review
Anesthesiology
Alexandre Tran, Jordan Heuser, Timothy Ramsay, Daniel M. McIsaac, Guillaume Martel
Summary: Estimated blood loss (EBL) is a crucial tool for clinical decision-making and surgical outcomes research. In this systematic review of techniques for intraoperative blood loss estimation in major non-cardiac surgery, visual estimation was found to be the most studied and tended to provide lower EBL values compared to other methods. However, there is significant case-by-case variation and disagreement between techniques, suggesting the need for a universal, practical, and reproducible method for blood loss evaluation.
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2021)
Article
Pediatrics
Lei Shen, Mengyang Wang, Jingwei Zhao, Yuanyuan Ruan, Jingyi Yang, Songshan Chai, Xuan Dai, Bangkun Yang, Yuankun Cai, Yixuan Zhou, Zhimin Mei, Zhixin Zheng, Dongyuan Xu, Hantao Guo, Yu Lei, Runqi Cheng, Chuqiao Yue, Tiansheng Wang, Yunchang Zhao, Xinyu Liu, Yibo Chai, Jingcao Chen, Hao Du, Nanxiang Xiong
Summary: Obesity has a significant impact on surgical outcomes, but its relationship with pediatric epilepsy surgery has not been reported. This study aimed to explore the relationship between obesity and complications of pediatric epilepsy surgery and its effect on surgical outcomes, providing a reference for weight management in children with epilepsy.
Article
Dentistry, Oral Surgery & Medicine
Michael Schwaiger, Sarah-Jayne Edmondson, Jasmin Rabensteiner, Florian Prueller, Thomas Gary, Wolfgang Zemann, Juergen Wallner
Summary: Gender has an influence on blood loss and haemostatic profiles in bimaxillary surgery. Men tend to have higher intraoperative blood loss and 48-hour postoperative bleeding volume compared to women, but gender does not affect haemostatic profiles. Furthermore, the 48-hour postoperative bleeding volume is closely associated with gender-specific imbalances in the anticoagulant system.
CLINICAL ORAL INVESTIGATIONS
(2022)
Review
Medicine, General & Internal
Yibo Zhao, Chunyang Xi, Wenxiao Xu, Jinglong Yan
Summary: TXA administration effectively reduces blood loss and transfusion, improves hemoglobin levels, and increases preoperative platelet count in patients undergoing multilevel spine surgery, as shown by meta-analysis results.
Review
Surgery
Giampaolo Perri, Giovanni Marchegiani, Federico Reich, Luca Casetti, Martina Fontana, Alessandro Esposito, Andrea Ruzzenente, Roberto Salvia, Claudio Bassi
Summary: This study provides an overview of the current practice of intraoperative blood loss estimation in hepato-pancreato-biliary surgery. The findings suggest that the method of blood loss estimation is not standardized and calls for urgent standardization to ensure consistency and reproducibility.
Article
Medicine, General & Internal
Wei Dong, Yi Liang, Dongxu Li, Zhaoxin Ma, Minghuang Cheng, Xiaojun Zhang, Jieliang Shen, Nian Zhou, Jie Hao, Wei Jiang, Zhenming Hu
Summary: The study found that preoperative injection of 1g TXA combined with continuous injection for 1-3 days can reduce postoperative bleeding and shorten the time to drainage tube removal in patients undergoing posterior lumbar interbody fusion surgery. It can also inhibit the postoperative inflammatory response.
FRONTIERS IN MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Yafen Liang, Abhijeet Dhoble, Adarsh Pakanati, Yelin Zhao, Felix Kork, Wei Ruan, Travis Markham, Richard Smalling, Prakash Balan, Anthony Estrera, Tom C. Nguyen, Igor Gregoric, Biswajit Kar, Holger Eltzschig
Summary: Catastrophic cardiac events during TAVR are rare but significantly increase perioperative mortality. Causes include cardiac perforation, tamponade, aortic root disruption. Early recognition and standardized team approach are crucial for managing these complications and improving patient outcomes.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Clinical Neurology
Brett E. Youngerman, Matei A. Banu, Farhan Khan, Guy M. McKhann, Catherine A. Schevon, Jonathan R. Jagid, Iahn Cajigas, Christian B. Theodotou, Andrew Ko, Robert Buckley, Jeffrey G. Ojemann, John W. Miller, Adrian W. Laxton, Daniel E. Couture, Gautam S. Popli, Vivek P. Buch, Casey H. Halpern, Scheherazade Le, Ashwini D. Sharan, Michael R. Sperling, Ashesh D. Mehta, Dario J. Englot, Joseph S. Neimat, Peter E. Konrad, Sameer A. Sheth, Elliot G. Neal, Fernando L. Vale, Kathryn L. Holloway, Ellen L. Air, Jason M. Schwalb, Pierre-Francois D'Haese, Chengyuan Wu
Summary: Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive treatment option for drug-resistant mesial temporal lobe epilepsy (mTLE) with durable outcomes. Anterior temporal lobectomy (ATL) is a safe and effective treatment for patients who fail MRgLITT.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)