A refined model of chronic cerebral hypoperfusion resulting in cognitive impairment and a low mortality rate in rats

Combined gene therapy with vascular endothelial growth factor plus apelin in a chronic cerebral hypoperfusion model in rats

(2017) Masafumi Hiramatsu et al.   JOURNAL OF NEUROSURGERY

Bilateral common carotid artery stenosis in normotensive rats impairs endothelium-dependent dilation of parenchymal arterioles

(2016) Nusrat Matin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chronic cerebral hypoperfusion induces long-lasting cognitive deficits accompanied by long-term hippocampal silent synapses increase in rats

(2016) Zhiqiang Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory

(2016) Akihiro Kitamura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of exercise-induced neurogenesis on cognitive function deficit in a rat model of vascular dementia

(2016) DONG-HEE CHOI et al.   Molecular Medicine Reports

Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?

(2016) Si-Qi Du et al.   MOLECULAR NEUROBIOLOGY

Long-term effects of cerebral hypoperfusion on neural density and function using misery perfusion animal model

(2016) Asuka Nishino et al.   Scientific Reports

Models and mechanisms of vascular dementia

(2015) Poornima Venkat et al.   EXPERIMENTAL NEUROLOGY

Chronic Cerebral Hypoperfusion Induces Vascular Plasticity and Hemodynamics but Also Neuronal Degeneration and Cognitive Impairment

(2015) Zhen Jing et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

L-Carnitine Enhances Axonal Plasticity and Improves White-Matter Lesions after Chronic Hypoperfusion in Rat Brain

(2015) Yuji Ueno et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Novel Mouse Model of Subcortical Infarcts with Dementia

(2015) Y. Hattori et al.   JOURNAL OF NEUROSCIENCE

A modified bilateral carotid artery stenosis procedure to develop a chronic cerebral hypoperfusion rat model with an increased survival rate

(2015) Nan Li et al.   JOURNAL OF NEUROSCIENCE METHODS

Preconditioning with VEGF Enhances Angiogenic and Neuroprotective Effects of Bone Marrow Mononuclear Cell Transplantation in a Rat Model of Chronic Cerebral Hypoperfusion

(2015) Jianping Wang et al.   MOLECULAR NEUROBIOLOGY

Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region

(2015) Pan Luo et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

BMSCs transplantation improves cognitive impairment via up-regulation of hippocampal GABAergic system in a rat model of chronic cerebral hypoperfusion

(2015) Q. Long et al.   NEUROSCIENCE

Clonidine ameliorates cognitive impairment induced by chronic cerebral hypoperfusion via up-regulation of the GABABR1 and GAD67 in hippocampal CA1 in rats

(2015) Yun Lu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF–VEGFR2 signaling pathway in a rat model of vascular dementia

(2014) Jianping Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Bilateral Common Carotid Artery Occlusion in the Rat as a Model of Retinal Ischaemia

(2014) Yingxiang Huang et al.   NEURO-OPHTHALMOLOGY

The Ins and Outs of the BCCAo Model for Chronic Hypoperfusion: A Multimodal and Longitudinal MRI Approach

(2013) Guadalupe Soria et al.   PLoS One

Sildenafil provides sustained neuroprotection in the absence of learning recovery following the 4-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion in middle-aged rats

(2012) Emilene Dias Fiuza Ferreira et al.   BRAIN RESEARCH BULLETIN

Cognitive functions of carotid artery stenosis in the aged rat

(2012) Z. Zhou et al.   NEUROSCIENCE

Chronic brain hypoperfusion causes early glial activation and neuronal death, and subsequent long-term memory impairment

(2011) Fernanda Cechetti et al.   BRAIN RESEARCH BULLETIN

Cognitive dysfunction induced by chronic cerebral hypoperfusion in a rat model associated with arteriovenous malformations

(2009) Jian Hai et al.   BRAIN RESEARCH

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

(2008) Kazunori Miki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice

(2007) Kaichi Yoshizaki et al.   EXPERIMENTAL NEUROLOGY