Review
Clinical Neurology
Abhishek Lenka, Joseph Jankovic
Summary: Tremor is a common movement disorder in clinical practice, with a wide range of pathologies. The International Parkinson Disease and Movement Disorders Society has proposed a new classification system based on clinical features and etiology, which has become a significant topic in scientific discussions on tremor.
FRONTIERS IN NEUROLOGY
(2021)
Review
Clinical Neurology
Guenther Deuschl, Jos S. Becktepe, Michiel Dirkx, Dietrich Haubenberger, Anhar Hassan, Rick C. Helmich, Muthuraman Muthuraman, Pattamon Panyakaew, Petra Schwingenschuh, Kirsten E. Zeuner, Rodger J. Elble
Summary: The various forms of tremor are now classified based on clinical characteristics and etiology. Electrophysiology, as an extension of clinical examination, is valuable in diagnosing and characterizing different types of tremor. It also plays a crucial role in understanding the pathophysiology of tremor.
CLINICAL NEUROPHYSIOLOGY
(2022)
Review
Clinical Neurology
Karen Frei, Daniel D. Truong
Summary: Tremor is a common movement disorder that can occur in various neurological conditions. This article reviews the efficacy of different medications for tremor treatment and discusses the pharmacological approaches for different types of tremor.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Review
Clinical Neurology
Elan D. Louis, Peter G. Bain
Summary: This article introduces the Consensus Statement on the Classification of Tremors published by the Task Force of the International Parkinson's and Movement Disorder Society in 2018, highlighting the problems in the classification and proposing several suggestions, such as redefining essential tremor, emphasizing the importance of severity in classifying and diagnosing tremors, and establishing rules for creating a hierarchy of terminology.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Article
Medicine, General & Internal
Abdulnasir Hossen, Abdul Rauf Anwar, Nabin Koirala, Hao Ding, Dmitry Budker, Arne Wickenbrock, Ulrich Heute, Sergiu Groppa, Muthuraman Muthuraman, Gunther Deuschl
Summary: This study proposes a classification method for distinguishing multiple sclerosis (MS) tremors from other forms of cerebellar tremors. By using electromyogram (EMG), accelerometer, and clinical data, the researchers developed an analytical framework and achieved high classification accuracy. The results demonstrate the potential of this method as a complement to tremor diagnosis in MS patients.
Article
Neurosciences
Jeyeon Lee, Jiwon Kim, Joshua Cortez, Su-Youne Chang
Summary: By using a rat HA-induced tremor model, this study investigated the electrophysiological response of the motor circuit, including the vlTh and M1, and the modulatory effect of thalamic DBS. The results showed that theta and HFO band powers significantly increased in both vlTh and M1 after HA administration, and this activity was modulated by propranolol and thalamic DBS. Theta band phase synchronization between vlTh and M1 was enhanced during HA-induced tremor, and the cross-frequency coupling in vlTh was associated with the state of HA-induced tremor.
EXPERIMENTAL NEUROLOGY
(2022)
Review
Clinical Neurology
N. Nsengiyumva, A. Barakat, A. Macerollo, R. Pullicino, A. Bleakley, M. Bonello, R. J. B. Ellis, S. H. Alusi
Summary: Holmes Tremor (HT) is a unique and debilitating movement disorder that can result from midbrain or thalamic lesions. Clinical examination can aid in localization, with HT-m characterized by different tremor features compared to HT-t. Lesion localization can have implications for management strategies.
JOURNAL OF NEUROLOGY
(2021)
Article
Neuroimaging
Patrick Bedard, Pattamon Panyakaew, Hyun-Joo Cho, Mark Hallett, Silvina G. Horovitz
Summary: This study aimed to understand the differential pathophysiology of essential tremor and dystonic tremor. The results showed altered functional connectivity in the cerebellum for essential tremor patients, higher fractional anisotropy in the middle cerebellar peduncle for dystonic tremor patients, and reduced mean diffusivity in the cerebellum for both tremor groups. The findings suggest that the cerebellum is affected differently in both essential tremor and dystonic tremor.
NEUROIMAGE-CLINICAL
(2022)
Article
Multidisciplinary Sciences
Takeshi Nishimura, Kentaro Emoto, Hisashi Nakahara, Satoshi Miura, Mare Yamamoto, Shunsuke Sugimura, Ayumu Ishikawa, Tsunehisa Kimura
Summary: This study presents a novel method for source location determination of volcanic earthquakes and characterization of volcanic subsurfaces using a distributed acoustic sensing (DAS) system. By analyzing well-correlated waveforms and seismic amplitudes recorded along a fiber-optic cable, the hypocenters of volcanic earthquakes at Azuma volcano, Japan were successfully determined, showing a shallow depth beneath active volcanic areas. The spatial distribution of site amplification factors from coda waves of regional tectonic earthquakes is correlated with old lava flow distributions and volcano topography.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Nikki Delgado, Diane S. Berry, Elan D. Louis
Summary: This study provides detailed examination of rest tremor and finds that it often lateralizes with other types of tremors in essential tremor (ET), adding to our understanding of the phenotypic manifestations of ET.
PARKINSONISM & RELATED DISORDERS
(2022)
Article
Geriatrics & Gerontology
Xitong Xu, Jie Chen, Shaozhen Ji, Zhuqin Gu, Meijie Chen, Jagadish Kumar Chhetri, Piu Chan
Summary: This study found an association between postural tremor in older adults and ADL disability, particularly in the mobility domain of ADL. The increased risk of disability was mainly due to older age and a higher prevalence of chronic comorbidities in older people with postural tremor. Postural tremor was not a strong independent predictor of ADL disability in older people.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geochemistry & Geophysics
Chao Song, Allan M. Rubin
Summary: Researchers investigated tremor signals by locating windows in different frequency bands, finding that during rapid tremor migrations, low-frequency energy appears to lag behind high-frequency energy by roughly 500 meters. This suggests that tremor may consist of more than just a collection of LFEs.
JOURNAL OF GEOPHYSICAL RESEARCH-SOLID EARTH
(2021)
Review
Clinical Neurology
Anna Latorre, Mark Hallett, Guenther Deuschl, Kailash P. Bhatia
Summary: In 2018, the new Consensus Statement on the Classification of Tremors was published by the Task Force on Tremor of the International Parkinson Movement Disorder Society. The article has gained significant attention, being cited over 400 times and sparking discussions in conferences and meetings. The main novelties of the classification include the syndromic approach, the definition of essential tremor as a syndrome, and the recognition of essential tremor plus. This comprehensive and rigorous classification is deemed the best current approach based on our current knowledge of tremor syndromes.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Luca Angelini, Giulia Paparella, Alessandro De Biase, Annalisa Maraone, Matteo Panfili, Isabella Berardelli, Antonio Cannavacciuolo, Antonella Di Vita, Roberta Margiotta, Giovanni Fabbrini, Alfredo Berardelli, Matteo Bologna
Summary: This study investigated the progression of Essential Tremor (ET) manifestations through clinical and neurophysiological evaluation. The results showed that ET progression is characterized by the spread of tremor in multiple body segments and the emergence of soft signs. Female sex, absence of family history, and rest tremor at baseline were identified as predictive factors of worse disease progression.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Food Science & Technology
David P. Newland, Daniel Novakovic, Amanda L. Richards
Summary: Voice tremor is a common symptom for patients with tremor-associated disorders, and understanding its pathophysiology and accurate diagnosis are crucial for effective treatment. This review provides an updated understanding of voice tremor and the role of botulinum neurotoxin, emphasizing the importance of detailed patient characterization and further research on targeted treatment options.
