Increased expression of glutamate transporter GLT-1 in peritumoral tissue associated with prolonged survival and decreases in tumor growth in a rat model of experimental malignant glioma

Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus

(2012) Qiongman Kong et al.   NEUROBIOLOGY OF DISEASE

Glutamate is associated with a higher risk of seizures in patients with gliomas

(2012) T. I. Yuen et al.   NEUROLOGY

Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation of cue- and cocaine-primed reinstatement of cocaine-seeking

(2011) Ilan Sondheimer et al.   BEHAVIOURAL BRAIN RESEARCH

Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity

(2011) S.-G. Lee et al.   CANCER RESEARCH

Human nasal olfactory epithelium as a dynamic marker for CNS therapy development

(2011) Rita Sattler et al.   EXPERIMENTAL NEUROLOGY

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

Phase 2 trial of talampanel, a glutamate receptor inhibitor, for adults with recurrent malignant gliomas

(2010) Fabio M. Iwamoto et al.   CANCER

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex

(2010) Ling-Hui Zeng et al.   NEUROBIOLOGY OF DISEASE

Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression

(2010) Yun Li et al.   NEUROPHARMACOLOGY

Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders

(2010) K.M. Ramos et al.   NEUROSCIENCE

Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas

(2010) N E Savaskan et al.   ONCOGENE

Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of Sulfasalazine for the treatment of progressing malignant gliomas in adults

(2009) Pierre A Robe et al.   BMC CANCER

Genetic alterations and signaling pathways in the evolution of gliomas

(2009) Hiroko Ohgaki et al.   CANCER SCIENCE

Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat

(2009) Nicolas Vanhoutte et al.   EXPERIMENTAL NEUROLOGY

Talampanel With Standard Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma: A Multicenter Phase II Trial

(2009) Stuart A. Grossman et al.   JOURNAL OF CLINICAL ONCOLOGY

In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines

(2009) Hani J. Marcus et al.   JOURNAL OF NEURO-ONCOLOGY

Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-κB

(2009) W. Joon Chung et al.   JOURNAL OF NEUROCHEMISTRY

A thermal gel depot for local delivery of paclitaxel to treat experimental brain tumors in rats

(2009) Betty Tyler et al.   JOURNAL OF NEUROSURGERY

Attenuated AMPA Receptor Expression Allows Glioblastoma Cell Survival in Glutamate-Rich Environment

(2009) Dannis G. van Vuurden et al.   PLoS One

Beneficial Effects of Ceftriaxone Against Pentylenetetrazole-Evoked Convulsions

(2008) Ankica V. Jelenkovic et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke

(2008) Christa Thöne-Reineke et al.   JOURNAL OF HYPERTENSION

Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation

(2008) John F. de Groot et al.   JOURNAL OF NEURO-ONCOLOGY

Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema

(2008) Nicolai E Savaskan et al.   NATURE MEDICINE

Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia

(2008) Sunil K. Hota et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Neuroprotection for ischemic stroke: Past, present and future

(2008) Myron D. Ginsberg   NEUROPHARMACOLOGY

Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

(2008) B.R. Miller et al.   NEUROSCIENCE