Journal
JOURNAL OF NEUROSURGERY
Volume 116, Issue 5, Pages 972-977Publisher
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2012.1.JNS111627
Keywords
bevacizumab; arteriovenous malformation; edema; stereotactic radiosurgery
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The authors present a case of an arteriovenous malformation of the central sulcus treated with Gamma Knife surgery. The patient developed perilesional edema 9 months after treatment and experienced severe headache and hemiparesis. Her symptoms were refractory to corticosteroid therapy and pain management. She was subsequently treated with bevacizumab with striking improvement in her symptoms and results of neuroimaging studies. This is the first time that bevacizumab has been used to control severe refractory perilesional edema related to an intracranial. arteriovenous malformation. (http://thejns.org/doi/abs/10.3171/2012.1.JNS111627)
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