Article
Oncology
In-Ho Jung, Jihwan Yoo, Seonah Choi, Seung Hoon Lim, JaeSang Ko, Tae Hoon Roh, Je Beom Hong, Eui Hyun Kim
Summary: The study demonstrates the feasibility and efficacy of endoscopic transorbital approach (ETOA) in accessing and exploring the cavernous sinus (CS) in skull base tumors. The ETOA provides a unique and valuable surgical route to the CS, especially for the lateral and posterior compartments, and can be used in synergy with other surgical approaches.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Congxin Dai, Ming Feng, Lin Lu, Bowen Sun, Yanghua Fan, Xinjie Bao, Yong Yao, Kan Deng, Renzhi Wang, Jun Kang
Summary: Transsphenoidal surgery (TSS) is the primary treatment for corticotroph adenomas, but managing cases with cavernous sinus invasion (CSI) remains challenging. This study evaluated surgical outcomes in patients with CSI, finding that about half of them achieved biochemical remission after TSS, but additional treatments might be necessary for those who do not respond to surgery.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
In-Ho Jung, Seonah Choi, Cheol Ryong Ku, Sang-Guk Lee, Eun Jig Lee, Sun Ho Kim, Eui Hyun Kim
Summary: This study evaluated the reliability of IGF-1 levels as an alternative for disease monitoring after surgical treatment of acromegaly. The results showed that IGF-1 levels can serve as a reliable alternative to OGTT and play a valuable role in monitoring acromegaly status.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Clinical Neurology
Austin C. Robbins, K. Austin Winter, Zachary P. Smalley, Saniya Godil, Gustavo Luzardo, Chad W. Washington, Daniel M. Prevedello, Scott P. Stringer, Marcus Zachariah
Summary: This study describes the use of a side-firing ultrasound probe in the resection of giant pituitary macroadenomas. The side-firing ultrasound probe allows for identification of the diaphragma sellae, confirmation of optic chiasm decompression, identification of vascular structures related to tumor invasion, and maximizing extent of resection in giant pituitary macroadenomas.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Evan D. Bander, Joseph A. Carnevale, Umberto Tosi, Kyle J. Godfrey, Theodore H. Schwartz
Summary: The lateral transorbital approach (LTOA) is a minimally invasive surgical technique that provides direct access to the cavernous sinus. A retrospective study of CS lesions treated by LTOA showed successful outcomes in all six cases, with an average extent of resection of 64.6%. Improvement in preoperative cranial neuropathies was observed in half of the patients, and there were no new permanent cranial neuropathies. Only one patient had a vascular injury, which was repaired endovascularly without neurological deficits.
OPERATIVE NEUROSURGERY
(2023)
Review
Medicine, Research & Experimental
Jacobo Kerbel, Amayrani Cano-Zaragoza, Rodrigo Espinosa-Dorado, Keren-Enid Garcia de la Torre, Moises Mercado
Summary: National registries are valuable tools to investigate rare conditions like acromegaly, providing insights into epidemiology, clinical presentation, diagnosis, treatment outcomes, and mortality. While single-center studies are more homogeneous, they are often limited by small sample sizes and lack statistical power.
ARCHIVES OF MEDICAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Juan Manuel Canelo Moreno, Elena Dios Fuentes, Eva Venegas Moreno, Pablo Jesus Remon Ruiz, Cristina Munoz Gomez, Ana Pinar Gutierrez, Eugenio Cardenas Valdepenas, Ariel Kaen, Alfonso Soto Moreno
Summary: This study aimed to investigate the prevalence and predictive factors of water and electrolyte disturbances in patients undergoing surgery with an extended endoscopic endonasal approach. The study found a high prevalence of electrolyte disturbances, with most cases being transient hypotonic polyuria and a smaller proportion being transient or permanent diabetes insipidus.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Otorhinolaryngology
Mohannad A. Al-Qudah
Summary: This study showed that intraoperative irrigation with saline-epinephrine solution at a concentration of 1:100,000 is safe and does not affect heart rate or blood pressure, but is unlikely to improve the setting of intraoperative surgical field, except for reducing blood loss in patients with high Lund-Mackay scores.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Clinical Neurology
Aislyn C. C. DiRisio, Rui Feng, William H. H. Shuman, Samantha Platt, Gabrielle Price, Jonathan T. T. Dullea, Shivee Gilja, Megan R. R. D'Andrea, Bradley N. N. Delman, Joshua B. B. Bederson, Raj K. K. Shrivastava
Summary: This study evaluates an alternative method using 3-dimensional volumetric imaging to better predict extent of resection in nonfunctional pituitary adenomas. The results suggest that increasing use of volumetric 3D imaging may better anticipate extent of resection compared with the Knosp grade metric and may have a greater positive predictive value for gross total resection.
Article
Clinical Neurology
Shunya Hanakita, Masahiro Shin, Hirotaka Hasegawa, Masaaki Shojima, Kenta Ohara, Yuki Shinya, Mariko Kawashima, Kenji Kondo, Nobuhito Saito
Summary: Surgical resection of tumors invading the cavernous sinus remains challenging. This study shows that endoscopic transsphenoidal surgery (ETS) can achieve sufficient surgical resection in most patients with acceptable neurological complications. ETS may offer the opportunity for improving cranial nerve functions in patients with cranial nerve symptoms.
OPERATIVE NEUROSURGERY
(2023)
Article
Oncology
Felix Ehret, Markus Kufeld, Christoph Fuerweger, Alfred Haidenberger, Paul Windisch, Susanne Fichte, Ralph Lehrke, Carolin Senger, David Kaul, Daniel Ruess, Maximilian Ruge, Christian Schichor, Joerg-Christian Tonn, Guenter Stalla, Alexander Muacevic
Summary: In addition to surgery and medication, robotic radiosurgery is an effective and safe treatment option for growth hormone-secreting tumors of the pituitary gland infiltrating surrounding tissue structures, achieving biochemical disease control or remission in most patients with decreasing hormone levels. The treatment also demonstrates favorable risk and safety profiles.
Article
Clinical Neurology
Marcus A. Zachariah, Jordan J. Bozer, Santino Cua, Luciano M. Prevedello, Luma M. Ghalib, Douglas A. Hardesty, Ricardo L. Carrau, Lawrence S. Kirschner, Daniel M. Prevedello
Summary: This study aimed to evaluate whether intraoperative GH measurement could predict long-term outcomes for acromegaly adenomectomy. The results showed that the minimum intraoperative GH level could predict long-term outcomes for acromegaly.
OPERATIVE NEUROSURGERY
(2023)
Article
Clinical Neurology
Rupa G. Juthani, Anne S. Reiner, Ankur R. Patel, Aimee Cowan, Marie Roguski, Katherine S. Panageas, Eliza B. Geer, Sasan Karimi, Marc A. Cohen, Viviane Tabar
Summary: The study evaluated the safety and efficacy of iMRI for pituitary adenoma resection, comparing endoscopic transsphenoidal and microscopic transsphenoidal approaches. Results showed that iMRI can improve the extent of resection for pituitary adenomas while preserving hormone function, with low rates of postoperative complications.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Takakazu Kawamata, Kosaku Amano
Summary: The newly developed bendable ring curette can improve maneuverability and accessibility, making it a promising tool for use in pituitary surgeries.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Lijun Heng, Hang Wang, Shuo Zhang, Xue Jiang, Yan Qu
Summary: The cavernous sinus molding technique with hemostatic agent injection during endoscopic endonasal pituitary surgery is a practical, effective, and safe method for controlling intracavernous bleeding. It involves making a small incision in the cavernous sinus wall, injecting the hemostatic agent along the venous channels to establish partial molding, and using tailored instruments for injection. Multi-spot injections are preferred for better bleeding control and reducing complications. Postoperative complications were not observed in the patients treated with this technique.
ACTA NEUROCHIRURGICA
(2022)