Pathogenic role of ganglioside metabolism in neurodegenerative diseases

Chaperone therapy update: Fabry disease, GM1-gangliosidosis and Gaucher disease

(2013) Yoshiyuki Suzuki   BRAIN & DEVELOPMENT

Effects of Amyloid β-Peptides and Gangliosides on Mouse Neural Stem Cells

(2013) Yutaka Itokazu et al.   NEUROCHEMICAL RESEARCH

Altered Distribution of the Gangliosides GM1 and GM2 in Alzheimer’s Disease

(2012) Z. Pernber et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

(2012) Gusheng Wu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

(2012) A. Di Pardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging drugs for amyotrophic lateral sclerosis

(2011) Ali Aamer Habib et al.   EXPERT OPINION ON EMERGING DRUGS

Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain

(2011) Julian R. Arthur et al.   JOURNAL OF LIPID RESEARCH

Lysosomal accumulation of Trk protein in brain of GM1-gangliosidosis mouse and its restoration by chemical chaperone

(2011) Ayumi Takamura et al.   JOURNAL OF NEUROCHEMISTRY

New approach for glyco- and lipidomics - Molecular scanning of human brain gangliosides by TLC-Blot and MALDI-QIT-TOF MS

(2011) Tania Valdes-Gonzalez et al.   JOURNAL OF NEUROCHEMISTRY

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(2011) Noemi Fabelo et al.   MOLECULAR MEDICINE

Disialogangliosides and TNFα Alter Gene Expression for Cytokines and Chemokines in Primary Brain Cell Cultures

(2011) Donna M. Byers et al.   NEUROCHEMICAL RESEARCH

Regulatory Mechanisms of Nervous Systems with Glycosphingolipids

(2011) Koichi Furukawa et al.   NEUROCHEMICAL RESEARCH

Mice Lacking Major Brain Gangliosides Develop Parkinsonism

(2011) Gusheng Wu et al.   NEUROCHEMICAL RESEARCH

Lyso-GM2 Ganglioside: A Possible Biomarker of Tay-Sachs Disease and Sandhoff Disease

(2011) Takashi Kodama et al.   PLoS One

Anti-neural antibodies in serum and cerebrospinal fluid of amyotrophic lateral sclerosis (ALS) patients

(2010) I. Niebroj-Dobosz et al.   ACTA NEUROLOGICA SCANDINAVICA

Lipid rafts: Keys to neurodegeneration

(2010) Cara-Lynne Schengrund   BRAIN RESEARCH BULLETIN

Angiokeratoma corporis diffusum in GM1 gangliosidosis, Type 1

(2010) Nicholas G. Beratis et al.   CLINICAL GENETICS

Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function

(2010) Yasuteru Sano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glycosphingolipid storage leads to the enhanced degradation of the B cell receptor in Sandhoff disease mice

(2010) Danielle te Vruchte et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington’s disease

(2010) Christine A. Denny et al.   JOURNAL OF NEUROCHEMISTRY

Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1

(2010) V. Maglione et al.   JOURNAL OF NEUROSCIENCE

Activation of Adenosine A2A Receptors Induces TrkB Translocation and Increases BDNF-Mediated Phospho-TrkB Localization in Lipid Rafts: Implications for Neuromodulation

(2010) N. Assaife-Lopes et al.   JOURNAL OF NEUROSCIENCE

GM1 ganglioside in Parkinson's disease: Results of a five year open study

(2010) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders

(2010) Marco Piccinini et al.   MOLECULAR NEUROBIOLOGY

Stem Cell Glycolipids

(2010) Makoto Yanagisawa   NEUROCHEMICAL RESEARCH

Exogenous gangliosides increase the release of brain-derived neurotrophic factor

(2010) Seung T. Lim et al.   NEUROPHARMACOLOGY

Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord

(2009) Jianjun Zhai et al.   FEBS Journal

PARKINSON’S DISEASE, AUTOIMMUNITY, AND OLFACTION

(2009) MICHAL BENKLER et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

On the mechanism of internalization of α-synuclein into microglia: roles of ganglioside GM1 and lipid raft

(2009) Ji-Young Park et al.   JOURNAL OF NEUROCHEMISTRY

Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

(2009) Antonio Valencia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amyotrophic lateral sclerosis associated with IgG anti-GalNAc-GD1a antibodies

(2008) Toshihiro Yamazaki et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged and Alzheimer patients

(2008) L. Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Thematic Review Series: Sphingolipids.Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review,

(2008) Toshio Ariga et al.   JOURNAL OF LIPID RESEARCH

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis

(2008) Elena Elliot-Smith et al.   MOLECULAR GENETICS AND METABOLISM

LRRK2 MUTATION ANALYSIS IN PARKINSON DISEASE FAMILIES WITH EVIDENCE OF LINKAGE TO PARK8

(2008) V. Bonifati et al.   NEUROLOGY