The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons
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Title
The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons
Authors
Keywords
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Journal
JOURNAL OF NEUROSCIENCE RESEARCH
Volume 89, Issue 11, Pages 1802-1811
Publisher
Wiley
Online
2011-08-08
DOI
10.1002/jnr.22723
References
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Related references
Note: Only part of the references are listed.- Post-translational modifications of tau protein: Implications for Alzheimer's disease
- (2011) Ludovic Martin et al. NEUROCHEMISTRY INTERNATIONAL
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- (2010) Yong-Whan Lim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation
- (2010) David O Azorsa et al. BMC GENOMICS
- An okadaic acid-induced model of tauopathy and cognitive deficiency
- (2010) Zhang Zhang et al. BRAIN RESEARCH
- Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner
- (2010) Zhang Zhang et al. BRAIN RESEARCH
- Indirubin-3'-monoxime rescues spatial memory deficits and attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer's disease
- (2010) Yun Ding et al. NEUROBIOLOGY OF DISEASE
- Mechanisms of tau-induced neurodegeneration
- (2009) Khalid Iqbal et al. ACTA NEUROPATHOLOGICA
- Conformational Changes Specific for Pseudophosphorylation at Serine 262 Selectively Impair Binding of Tau to Microtubules
- (2009) Daniela Fischer et al. BIOCHEMISTRY
- Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
- (2009) Diane P. Hanger et al. TRENDS IN MOLECULAR MEDICINE
- Inhibition of glycogen synthase kinase-3β downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A
- (2008) Ludovic Martin et al. BRAIN RESEARCH
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
- (2008) G Kroemer et al. CELL DEATH AND DIFFERENTIATION
- Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease
- (2008) C.-X. Gong et al. CURRENT MEDICINAL CHEMISTRY
- I PP2A 1 Affects Tau Phosphorylation via Association with the Catalytic Subunit of Protein Phosphatase 2A
- (2008) She Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation
- (2008) Sadasivam Jeganathan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Soluble 3′,6-Substituted Indirubins with Enhanced Selectivity toward Glycogen Synthase Kinase -3 Alter Circadian Period
- (2008) Konstantina Vougogiannopoulou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Temporal correlation of the memory deficit with Alzheimer-like lesions induced by activation of glycogen synthase kinase-3
- (2008) Yue Wang et al. JOURNAL OF NEUROCHEMISTRY
- Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation
- (2008) Yanhui Xu et al. MOLECULAR CELL
- GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals
- (2008) Shuxin Hu et al. NEUROBIOLOGY OF DISEASE
- PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)
- (2008) Veerle Janssens et al. TRENDS IN BIOCHEMICAL SCIENCES
- Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms
- (2007) Gong-Ping Liu et al. NEUROBIOLOGY OF AGING
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