Article
Multidisciplinary Sciences
Clement M. Garin, Marie Garin, Leonardo Silenzi, Rye Jaffe, Christos Constantinidis
Summary: The size of the prefrontal cortex in humans is not disproportionately enlarged compared to other catarrhini species. However, humans have the most relatively enlarged frontal and parietal lobes in an infraorder exhibiting a disproportionate expansion of these areas.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
Charalampos Papadimitriou, Charles D. Holmes, Lawrence H. Snyder
Summary: The study finds that the dynamics of memory cells during spatial memory periods are more complex than previously thought. They suggest that memory may be supported by multiple attractor networks working in parallel, with each network having its own characteristic mean turn-off time that gradually frees up mnemonic resources over time.
Article
Multidisciplinary Sciences
Bin A. Wang, Maike Veismann, Abhishek Banerjee, Burkhard Pleger
Summary: The study reveals that the orbitofrontal cortex (OFC) interacts with the primary somatosensory cortex (S1) to guide flexible tactile learning in humans. The OFC has transient responses to unexpected outcomes, while the S1 is persistently engaged during re-learning. These findings suggest that the OFC contributes to dynamically updating representations in sensory areas through top-down signals to implement computations critical for adaptive behavior.
NATURE COMMUNICATIONS
(2023)
Article
Biology
Kiri Kuroda, Yukiko Ogura, Akitoshi Ogawa, Tomoya Tamei, Kazushi Ikeda, Tatsuya Kameda
Summary: In the digital era, new socially shared realities and norms emerge rapidly through social interactions. These interactions promote convergence of perceptual responses among people, resulting in shared generative models and agreement on new targets.
COMMUNICATIONS BIOLOGY
(2022)
Article
Biology
Neville Magielse, Roberto Toro, Vanessa Steigauf, Mahta Abbaspour, Simon B. Eickhoff, Katja Heuer, Sofie L. Valk
Summary: This study examines the evolution of the volumes of cerebellum and ansiforms in primates. The results suggest proportional scaling between cerebellum and cerebrum, while ansiforms have expanded faster. This indicates a general structural reorganization of ansiforms in primates, which is relevant for specialized brain functions.
COMMUNICATIONS BIOLOGY
(2023)
Article
Neurosciences
Wenhao Dang, Russell J. Jaffe, Xue-Lian Qi, Christos Constantinidis
Summary: The study found that training induced a modest increase in the proportion of PFC neurons with NMS exclusively for spatial working memory, but not for shape working memory tasks; additionally, increasing working memory task complexity did not increase the degree of NMS for stimulus shape with other task variables; and there was no evidence found that NMS is predictive of task performance.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Sihai Li, Christos Constantinidis, Xue-Lian Qi
Summary: The study investigated the roles of the dorsolateral prefrontal cortex and posterior parietal cortex in working memory, finding that neuronal activity can predict categorical judgments of information and deviations in firing rates reflect the contents of working memory.
Article
Neurosciences
Zhengyang Wang, Balbir Singh, Xin Zhou, Christos Constantinidis
Summary: Working memory ability continues to mature into adulthood in humans and nonhuman primates. Adolescent development is characterized by increased frontal firing rate in the delay period, but less is known about the coordinated activity between neurons. This study found that there was higher power in the gamma frequency range in both the cue and delay period in adolescents compared to adults. These changes were observed in various recording sites and could not be explained by performance differences.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yixin Tian, Jiapeng Yin, Chengyao Wang, Zhenliang He, Jingyi Xie, Xiaoshan Feng, Yang Zhou, Tianyu Ma, Yang Xie, Xue Li, Tianming Yang, Chi Ren, Chengyu Li, Zhengtuo Zhao
Summary: Researchers have developed a mechanically robust ultraflexible electrode array, the MERF, for high-density, large-scale, and chronic recording of neurons in the nonhuman primate brain. The MERF array has shown promising results in basic neuroscience studies and brain-machine interface applications.
Article
Neurosciences
Mohsen Parto Dezfouli, Philipp Schwedhelm, Michael Wibral, Stefan Treue, Mohammad Reza Daliri, Moein Esghaei
Summary: The study investigated visual feature binding across different dimensions using a novel stimulus configuration, demonstrating the involvement of the prefrontal cortex in this process and the dynamic modulation of low frequency inter-regional communication.
Review
Neurosciences
Margaux M. Kenwood, Ned H. Kalin
Summary: Studies show that nonhuman primates (NHPs) have anxiety-related temperaments similar to those of humans with behavioral inhibition, aiding in the design of translational models related to human psychopathology and providing insights into the neural systems underlying early risk for anxiety disorder development.
BIOLOGICAL PSYCHIATRY
(2021)
Review
Neurosciences
Laurence T. Hunt
Summary: There is a consensus that circuits in the prefrontal and anterior cingulate cortex play a critical role in reward-based decision making. The functional specialization of PFC/ACC circuits in humans and primates involve microcircuits that support persistent activity during cognitive tasks and macrocircuit connections that vary between different cytoarchitectonic subregions, contributing uniquely to reward-based decision tasks. This variation in circuit connections predicts distinctive neural representations in different regions of the brain during sequential attention-guided choice.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Review
Neurosciences
Jack T. Scott, James A. Bourne
Summary: Recent years have seen a resurgence in using NHPs to model human brain disorders, with modern techniques like optogenetics and calcium imaging enhancing research capabilities. However, behavioral experimentation and analysis methods in NHPs have not kept pace, requiring critical evaluation to improve integrity and translatability.
PROGRESS IN NEUROBIOLOGY
(2022)
Article
Behavioral Sciences
Philip T. Putnam, Steve W. C. Chang
Summary: The amygdala, located in the temporal lobes, is considered an important structure in neuroscience, associated not only with negative emotions but also playing a role in evaluating stimuli and shaping social behaviors. Modern studies have shown that the amygdala also processes positive emotions and social behaviors. Researchers are investigating the interaction between value-related processes and social stimulus processing in the amygdala.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Multidisciplinary Sciences
Yousang Yoon, Hyogeun Shin, Donghak Byun, Jiwan Woo, Yakdol Cho, Nakwon Choi, Il-Joo Cho
Summary: The authors present a wireless neural probe system with drug delivery capability for real-time monitoring of drug effects on both behavioral and neural activities in mice. The system allows for simultaneous monitoring of neural and behavioral changes and demonstrates dose-dependent and repeatable responses to drugs. The system is also used to analyze the changes in neural activity during modulated social interaction in pairs of mice. This technology provides new opportunities for studying the effects of drugs on behavior and neural activity.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Peter M. Kaskan, Vincent D. Costa, Hana P. Eaton, Julie A. Zemskova, Andrew R. Mitz, David A. Leopold, Leslie G. Ungerleider, Elisabeth A. Murray
Article
Neurosciences
Peter H. Rudebeck, Joshua A. Ripple, Andrew R. Mitz, Bruno B. Averbeck, Elisabeth A. Murray
JOURNAL OF NEUROSCIENCE
(2017)
Article
Biochemical Research Methods
Andrew R. Mitz, Ravi V. Chacko, Philip T. Putnam, Peter H. Rudebeck, Elisabeth A. Murray
JOURNAL OF NEUROSCIENCE METHODS
(2017)
Article
Biochemical Research Methods
Andrew R. Mitz, Ramon Bartolo, Richard C. Saunders, Philip G. Browning, Thomas Talbot, Bruno B. Averbeck
JOURNAL OF NEUROSCIENCE METHODS
(2017)
Article
Biology
Shan Yu, Tiago L. Ribeiro, Christian Meisel, Samantha Chou, Andrew Mitz, Richard Saunders, Dietmar Plenz
Review
Biochemistry & Molecular Biology
Andrew R. Mitz, Travis J. Philyaw, Luigi Boccuto, Aleksandr Shcheglovitov, Sara M. Sarasua, Walter E. Kaufmann, Audrey Thurm
EUROPEAN JOURNAL OF HUMAN GENETICS
(2018)
Article
Neurosciences
Tianming Yang, Rachel L. Bavley, Kevin Fomalont, Kevin J. Blomstrom, Andrew R. Mitz, Janita Turchi, Peter H. Rudebeck, Elisabeth A. Murray
Article
Neurosciences
Peter H. Rudebeck, Andrew R. Mitz, Ravi V. Chacko, Elisabeth A. Murray
Article
Multidisciplinary Sciences
Erik W. Schluter, Andrew R. Mitz, Joseph F. Cheer, Bruno B. Averbeck
Article
Multidisciplinary Sciences
Peter H. Rudebeck, Philip T. Putnam, Teresa E. Daniels, Tianming Yang, Andrew R. Mitz, Sarah E. V. Rhodes, Elisabeth A. Murray
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2014)
Letter
Genetics & Heredity
Luigi Boccuto, Ludovico Abenavoli, Lauren Cascio, Sujata Srikanth, Barbara DuPont, Andrew R. Mitz, Roger Curtis Rogers, Katy Phelan
Article
Neurosciences
Peter M. Kaskan, Aaron M. Dean, Mark A. Nicholas, Andrew R. Mitz, Elisabeth A. Murray
Article
Neurosciences
Vincent D. Costa, Andrew R. Mitz, Bruno B. Averbeck
Article
Neurosciences
Ramon Bartolo, Richard C. Saunders, Andrew R. Mitz, Bruno B. Averbeck
JOURNAL OF NEUROSCIENCE
(2020)
Article
Biochemical Research Methods
Aline Silva da Cruz, Maria Margarida Drehmer, Wagner Baetas-da-Cruz, Joao Carlos Machado
Summary: This study quantified microcirculation cerebral blood flow in a rat model of ischemic stroke using ultrasound biomicroscopy and ultrasound contrast agents. The results showed high sensitivity and specificity of this method, making it a valuable tool for preclinical studies.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Christina Dalla, Ivana Jaric, Pavlina Pavlidi, Georgia E. Hodes, Nikolaos Kokras, Anton Bespalov, Martien J. Kas, Thomas Steckler, Mohamed Kabbaj, Hanno Wuerbel, Jordan Marrocco, Jessica Tollkuhn, Rebecca Shansky, Debra Bangasser, Jill B. Becker, Margaret McCarthy, Chantelle Ferland-Beckham
Summary: Many funding agencies have emphasized the importance of considering sex as a biological variable in experimental design to improve the reproducibility and translational relevance of preclinical research. Omitting the female sex from experimental designs in neuroscience and pharmacology can result in biased or limited understanding of disease mechanisms. This article provides methodological considerations for incorporating sex as a biological variable in in vitro and in vivo experiments, including the influence of age and hormone levels, and proposes strategies to enhance methodological rigor and translational relevance in preclinical research.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Wenyu Gu, Dongxu Li, Jia-Hong Gao
Summary: We developed a precise and rapid method for positioning and labelling triaxial OPMs on a wearable magnetoencephalography (MEG) system, improving the efficiency of OPM positioning and labelling.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Kai Lin, Linhang Zhang, Jing Cai, Jiaqi Sun, Wenjie Cui, Guangda Liu
Summary: The article introduces an EEG feature map processing model for emotion recognition, which achieves significantly improved accuracy by fusing EEG information at different spatial scales and introducing a channel attention mechanism.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
John E. Parker, Asier Aristieta, Aryn H. Gittis, Jonathan E. Rubin
Summary: This work presents a toolbox that implements a methodology for automated classification of neural responses based on spike train recordings. The toolbox provides a user-friendly and efficient approach to detect various types of neuronal responses that may not be identified by traditional methods.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Yun Liang, Ke Bo, Sreenivasan Meyyappan, Mingzhou Ding
Summary: This study compared the performance of SVM and CNN on the same datasets and found that CNN achieved consistently higher classification accuracies. The classification accuracies of SVM and CNN were generally not correlated, and the heatmaps derived from them did not overlap significantly.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Antonino Visalli, Maria Montefinese, Giada Viviani, Livio Finos, Antonino Vallesi, Ettore Ambrosini
Summary: This study introduces an analytical strategy that allows the use of mixed-effects models (LMM) in mass univariate analyses of EEG data. The proposed method overcomes the computational costs and shows excellent performance properties, making it increasingly important in the field of neuroscience.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
Article
Biochemical Research Methods
Xavier Cano-Ferrer, Alexandra Tran -Van -Minh, Ede Rancz
Summary: This study developed a novel rotation platform for studying neural processes and spatial navigation. The platform is modular, affordable, and easy to build, and can be driven by the experimenter or animal movement. The research demonstrated the utility of the platform, which combines the benefits of head fixation and intact vestibular activity.
JOURNAL OF NEUROSCIENCE METHODS
(2024)
