Article
Clinical Neurology
Jongwook Kim, Byoungwoo Cha, Doyoung Lee, Jong Moon Kim, MinYoung Kim
Summary: High-frequency rTMS over the ipsilesional DLPFC has beneficial effects on cognition and mood recovery in patients with subacute stroke. The improvement in cognitive abilities is more significant in patients with left hemispheric lesions, while patients with right hemispheric lesions show greater improvement in cognition.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
Chun-Hung Chang, Wen-Lung Wang, Yu-Hui Shieh, Han-Yuan Peng, Chen-Syuan Ho, Hsin-Chi Tsai
Summary: This study reports the case of a 62-year-old male patient with treatment-refractory tinnitus and depression who significantly improved after undergoing low-frequency rTMS over the right-side dorsolateral prefrontal cortex and left auditory cortex area. The findings suggest that sequential stimulation of multiple brain regions using low-frequency rTMS may have clinical benefits for patients with tinnitus and depression.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Giovanni Martinotti, Mauro Pettorruso, Chiara Montemitro, Primavera Alessandra Spagnolo, Cecilia Acuti Martellucci, Francesco Di Carlo, Fabrizio Fanella, Massimo di Giannantonio
Summary: This study aimed to evaluate the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) in patients with cocaine use disorder (CUD). The results showed that active rTMS treatment significantly improved symptoms of CUD and particularly depressive symptoms. However, no significant differences were observed in cocaine craving and consumption between treatment groups.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2022)
Article
Anatomy & Morphology
Ahsan Khan, Jochen A. Mosbacher, Stephan E. Vogel, Mira Binder, Michael Wehovz, Arnulf Moshammer, Stefan Halverscheid, Kolja Pustelnik, Michael A. Nitsche, Raymond Kai-Yu Tong, Roland H. Grabner
Summary: This study investigates the effects of multi-session theta band stimulation on arithmetic training. The results suggest that repetitive stimulation can significantly alter resting-state functional connectivity, but it does not affect white matter structure integrity or behavioral performance.
BRAIN STRUCTURE & FUNCTION
(2023)
Article
Neurosciences
Li Tian, Shuai Ma, Yin Li, Meng-fei Zhao, Chang Xu, Chen Wang, Xin Zhang, Lei Gao
Summary: This study explored the clinical efficacy of rTMS in improving face processing in individuals with autism spectrum disorder (ASD) and found that two sessions of rTMS intervention improved both the autism rating scores and fixations on human faces in individuals with ASD, except for the percentage of eye fixation. Mediation analysis showed that the item of Adaptation to Change in the Childhood Autism Rating Scale (CARS) played a dominant role in mediating the improvement of eye gaze behavior in individuals with ASD by rTMS. This study revealed the mechanism of rTMS in improving eye gaze behavior in the autism population, deepened the understanding of the function of rTMS in treating social disorders in autism, and provided a reference for combined treatment for ASD.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Clinical Neurology
Nabil Izzaatie Mohamad Safiai, Nur Afiqah Mohamad, Hamidon Basri, Liyana Najwa Inche Mat, Fan Kee Hoo, Anna Misyail Abdul Rashid, Abdul Hanif Khan Yusof Khan, Wei Chao Loh, Janudin Baharin, Aaron Fernandez, Intan Nureslyna Samsudin, Mohd Hazmi Mohamed, Siew Mooi Ching, Kai Wei Lee, Vasudevan Ramachandran, Patricia Pozo-Rosich, Wan Aliaa Wan Sulaiman
Summary: High-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex may be effective in reducing acute medication intake and functional disability in migraine patients.
Article
Clinical Neurology
Hanall Lee, Joon Ho Lee, Moon-Hyon Hwang, Nyeonju Kang
Summary: This systematic review and meta-analysis investigated the potential effects of repetitive transcranial magnetic stimulation (rTMS) protocols on cardiovascular autonomic system (ANS) control. The results showed that applying excitatory and inhibitory rTMS protocols can significantly improve cardiovascular ANS control, reducing blood pressure and heart rate changes, and significantly improving heart rate variability. These improvements were observed when applying either excitatory rTMS protocols to the left dorsolateral prefrontal cortex or inhibitory rTMS protocols to the right dorsolateral prefrontal cortex. Overall, these findings suggest that applying excitatory and inhibitory rTMS protocols on prefrontal cortical regions may be effective in improving cardiovascular ANS control.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Computer Science, Interdisciplinary Applications
Mostafa Asgarinejad, Marzieh Saviz, Seyyed Mostafa Sadjadi, Sarah Saliminia, Amineh Kakaei, Peyman Esmaeili, Ahmad Hammoud, Elias Ebrahimzadeh, Hamid Soltanian-Zadeh
Summary: This review investigates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in improving cognitive abilities in healthy individuals, and explores the use of theta burst stimulation (TBS) wave patterns to enhance its effects. The results of this study can be beneficial for individuals in high-risk professions in terms of job performance.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2023)
Article
Psychiatry
Lei Gao, Chen Wang, Xiao-rong Song, Li Tian, Zhi-yi Qu, Yu Han, Xin Zhang
Summary: By using repetitive transcranial magnetic stimulation (rTMS) on children with autism spectrum disorder (ASD), the study found that this intervention could improve both core symptoms of ASD and comorbid sleep problems. Sensory abnormalities played a mediating role in the improvement of sleep problems in ASD children through rTMS intervention.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Neurosciences
Min Zhang, Runhua Wang, Xin Luo, Si Zhang, Xiaomei Zhong, Yuping Ning, Bin Zhang
Summary: Rapidly growing interest surrounds rTMS as a novel treatment for depression, but methodological weaknesses in existing research hinder its widespread clinical application. Variations in stimulated targets across the dorsolateral prefrontal cortex are believed to contribute to the heterogeneity in rTMS efficacy.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Giordano D'Urso, Michelangelo Dini, Marta Bonato, Silvia Gallucci, Marta Parazzini, Natale Maiorana, Marco Bortolomasi, Alberto Priori, Roberta Ferrucci
Summary: This open-label pilot study investigated the effect of combining bilateral cerebellar tDCS with bifrontal stimulation in patients with severe depression. The study found that after only five days of treatment, there was a 30% reduction in the severity of depressive symptoms, and younger patients showed greater clinical improvement.
Article
Psychiatry
Georgios Mikellides, Panayiota Michael, Lilia Psalta, Teresa Schuhmann, Alexander T. Sack
Summary: This study compares the acute antidepressive efficacy of intramuscular ketamine and repetitive transcranial magnetic stimulation (rTMS) therapy in patients with treatment resistant depression. The findings suggest that both therapies significantly improve depressive and anxiety symptoms with comparable efficacy.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Yoshinori Kadono, Keigo Koguchi, Ken-ichi Okada, Koichi Hosomi, Motoki Hiraishi, Takashi Ueguchi, Ikuhiro Kida, Adnan Shah, Guoxiang Liu, Youichi Saitoh
Summary: CPSP is a type of pain that occurs after a stroke near the somatosensory pathway, believed to be caused by maladaptive reorganization between various brain regions. Treatment options for CPSP are not well-established, but repetitive transcranial magnetic stimulation (rTMS) to the primary motor cortex has shown clinical efficacy in relieving pain in CPSP patients, possibly by modulating functional brain connectivity.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Yu-Ting Hu, Xi-Wen Hu, Jin-Fang Han, Jian-Feng Zhang, Ying-Ying Wang, Annemarie Wolff, Sara Tremblay, Dusan Hirjak, Zhong-Lin Tan, Georg Northoff
Summary: This study compared the therapeutic efficacy of rTMS at the left motor cortex (lMC) and left dorsolateral prefrontal cortex (lDLPFC) in MDD patients. The results showed no significant difference in treatment outcomes and tolerability between the two groups. The findings suggest that lMC can be a potential and easily accessible rTMS target.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Neurosciences
Aizawa Yuuichi, Joe Morishita, Michiko Kano, Motoyori Kanazawa, Shin Fukudo
Summary: The study suggests that stimulation of the right or left DPFC by rTMS can modify brain-gut interactions in humans, with low frequency rTMS significantly reducing visceral sensation and emotion scores, and high frequency rTMS increasing ACTH levels.
NEUROSCIENCE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Christina Dinter, Derik Hermann, Judith Heckmann, Holger Hill, Iris Reinhard, Sabine Vollstaedt-Klein, Peter Kirsch, Falk Kiefer
Article
Neurosciences
Phoebe Fehlner, Edda Bilek, Anais Harneit, Andreas Boehringer, Carolin Moessnang, Andreas Meyer-Lindenberg, Heike Tost
HUMAN BRAIN MAPPING
(2020)
Article
Neurosciences
Zhimin Yan, Stephanie N. L. Schmidt, Josef Frank, Stephanie H. Witt, Joachim Hass, Peter Kirsch, Daniela Mier
NEUROPSYCHOPHARMACOLOGY
(2020)
Article
Multidisciplinary Sciences
Sebastian Markett, Philippe Jawinski, Peter Kirsch, Martin F. Gerchen
SCIENTIFIC REPORTS
(2020)
Article
Behavioral Sciences
Stephanie N. L. Schmidt, Christian A. Sojer, Joachim Hass, Peter Kirsch, Daniela Mier
Article
Multidisciplinary Sciences
Silvia De Santis, Alejandro Cosa-Linan, Raquel Garcia-Hernandez, Lesia Dmytrenko, Lydia Vargova, Ivan Vorisek, Serena Stopponi, Patrick Bach, Peter Kirsch, Falk Kiefer, Roberto Ciccocioppo, Eva Sykova, David Moratal, Wolfgang H. Sommer, Santiago Canals
Article
Neurosciences
Gina-Isabelle Henze, Julian Konzok, Ludwig Kreuzpointner, Christoph Baertl, Hannah Peter, Marina Giglberger, Fabian Streit, Brigitte M. Kudielka, Peter Kirsch, Stefan Wuest
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
(2020)
Article
Neurosciences
Martin Fungisai Gerchen, Franziska Weiss, Martina Kirsch, Alena Rentsch, Patrick Halli, Falk Kiefer, Peter Kirsch
Summary: This study developed a circuit-specific fMRI analysis approach to detect dynamic changes in frontostriatal functional connectivity in AUD patients. The results consistently showed a ventral shift in right orbitofrontal cortex PeaCoG in AUD patients, and reduced temporospatial variability of dynamic PeaCoG in the left dorsolateral prefrontal cortex was associated with self-efficacy and days of abstinence.
HUMAN BRAIN MAPPING
(2021)
Article
Nutrition & Dietetics
Lierni Ugartemendia, Rafael Bravo, Martin Reuter, M. Yolanda Castano, Thomas Plieger, Vera Zamoscik, Peter Kirsch, Ana B. Rodriguez
Summary: This study aimed to improve age-related depression or social cognitive impairment through a tryptophan-enriched diet, showing a positive correlation in S'S' subjects. Factors such as age, genotype, and experimental conditions were important in influencing the outcomes of depression and social cognition.
CLINICAL NUTRITION
(2021)
Article
Neurosciences
Maria Bretzke, Nora C. Vetter, Gregor Kohls, Hannes Wahl, Veit Roessner, Michael M. Plichta, Judith Buse
Summary: This study investigates the role of uncertainty in loss processing and avoidance. The results show slower response times in adolescents compared to adults when it comes to avoiding loss, and adults show higher brain activation during the anticipation of potential monetary loss compared to adolescents.
COGNITIVE NEUROSCIENCE
(2023)
Article
Neurosciences
Edda Bilek, Peter Zeidman, Peter Kirsch, Heike Tost, Andreas Meyer-Lindenberg, Karl Friston
Summary: Advances in social neuroscience have enabled the measurement of neural signatures of social interaction, but the underlying mechanisms between brains are not fully understood. Dynamic causal modeling and Bayesian model comparison are used to assess the connectivity between two brains in hyperscanning contexts. The study reveals that effective connectivity between brains emerges selectively during social exchange and demonstrates a causal impact of sender's brain activity on information receivers, explaining reports of two-brain synchrony.
Article
Neurosciences
Florian Freudenberg, Heike Althen, Kim Falk, Robert A. Bittner, Andreas Reif, Michael M. Plichta
Summary: This study confirms the high test-retest reliability of the prepulse inhibition (PPI) in humans and validates its correlation with working memory (WM) performance. Detailed analysis suggests that PPI is regulated by cross-conditional processes such as attention, and there is a specific and significant correlation between 76 dB PPI condition and WM.
ACTA NEUROPSYCHIATRICA
(2022)
Article
Psychology, Educational
Ulrich Dettweiler, Martin Gerchen, Christoph Mall, Perikles Simon, Peter Kirsch
Summary: This study experimentally explored the effects of autonomy support and physical activity on the biological stress responses and brain development of students in education outside the classroom (EOtC). The results showed that EOtC students exhibited more efficient regulation of biological stress-reactivity and a reduction of cortisol associated with light physical activity in the forest. Additionally, the maturation of the anterior cingulate cortex (ACC) was positively influenced by autonomy support, especially in EOtC.
BRITISH JOURNAL OF EDUCATIONAL PSYCHOLOGY
(2023)
Article
Psychiatry
Kira F. Ahrens, Rebecca J. Neumann, Nina M. von Werthern, Thorsten M. Kranz, Bianca Kollmann, Bjoern Mattes, Lara M. C. Puhlmann, Danuta Weichert, Beat Lutz, Ulrike Basten, Christian J. Fiebach, Michele Wessa, Raffael Kalisch, Klaus Lieb, Andreas G. Chiocchetti, Oliver Tuscher, Andreas Reif, Michael M. Plichta
Summary: This study analyzed the relationship between risk scores for psychiatric phenotypes, hair cortisol concentrations (HCC), and mental health trajectories during the first COVID lockdown in Germany. The results indicated a significant association between risk scores and allocation to the acute dysfunction class. Elevated HCC was also found to be associated with childhood-onset neurodevelopmental disorders. These findings suggest the potential for future studies on risk prediction.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Vera Zamoscik, Stephanie N. L. Schmidt, Christina Timm, Christine Kuehner, Peter Kirsch