Review
Neurosciences
Mark A. Segraves
Summary: Using natural scenes as a research method provides insights into the functioning of visual and eye movement systems in everyday life. This review examines the findings from behavioral and neurophysiological studies using natural scene viewing in humans and monkeys. The use of natural scenes for studying cerebral cortical activity is relatively new and poses challenges for data analysis. The article presents methods and results from using natural scenes to study the visual and eye movement cortex, highlighting new insights that this approach offers to enhance our understanding of these cortical regions compared to conventional methods.
ANNUAL REVIEW OF VISION SCIENCE
(2023)
Article
Multidisciplinary Sciences
Panagiotis Sapountzis, Sofia Paneri, Sotirios Papadopoulos, Georgia G. Gregoriou
Summary: Recent work has shown that neural representations in the prefrontal cortex (PFC) are changing to adapt to task demands, but it is still unclear how this dynamic coding depends on the encoded variable and anatomical constraints. In this study, using a cued attention task and multivariate classification methods, the researchers found that neuronal ensembles in the PFC encode and retain spatial and color attentional instructions in a specific manner. Spatial instructions were decoded from both the frontal eye field (FEF) and the ventrolateral PFC (vlPFC) populations, while color instructions were decoded more robustly from vlPFC. The results suggest that dynamic population coding of attentional instructions in the PFC is influenced by anatomical constraints and can coexist with stable subspace coding.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Psychology, Experimental
Sven Ohl, Lisa M. Kroell, Martin Rolfs
Summary: Visual working memory and actions are closely related, as saccadic eye movements can select content in visual working memory and this selection is strongly linked to memory performance.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2023)
Article
Neurosciences
Emilio Salinas, Terrence R. Stanford
Summary: This study reveals that the choice of where to look next is influenced by both exogenous and endogenous factors, with their interaction details and unique contributions to target selection becoming clearer. Exogenous modulations associated with stimulus detection quickly and briefly interrupt ongoing motor plans according to spatial congruence rules, explaining characteristic features of various saccadic tasks. These low-level visuomotor interactions contribute to diverse oculomotor phenomena traditionally attributed to different neural mechanisms.
CURRENT OPINION IN NEUROBIOLOGY
(2021)
Review
Behavioral Sciences
Elena Borra, Giuseppe Luppino
Summary: This article discusses the potential homologies between macaques and humans in the oculomotor system, proposing a new perspective based on evidence from the past decade. It reveals the central role of FEF in the oculomotor domain in macaques and suggests a correspondence between some macaque and human oculomotor fields.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Acoustics
Kaleb A. Lowe, Wolf Zinke, M. Anthony Phipps, Josh Cosman, Micala Maddox, Jeffrey D. Schall, Charles F. Caskey
Summary: Research on focused ultrasound (FUS) stimulation directly applied over the macaque frontal eye field (FEF) through a craniotomy revealed that FUS can modulate saccadic responses in monkeys, affecting their saccade response times and error rates. FUS was found to have a regulatory effect on directing eye movements towards targets in visual search tasks.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Neurosciences
Yuan Zhang, Srikanth Ryali, Weidong Cai, Kaustubh Supekar, Ramkrishna Pasumarthy, Aarthi Padmanabhan, Bea Luna, Vinod Menon
Summary: The ability to adaptively respond to behaviorally relevant cues in the environment undergoes significant maturation from childhood to adulthood, and it influences the developmental trajectories of several key cognitive domains. However, little is known about the underlying causal functional circuit mechanisms. This study investigates the maturation of causal signaling mechanisms underlying voluntary control over saccades using state-space and control-theoretic modeling. The results show that directed causal interactions in a saccade network undergo significant maturation between childhood and adulthood, with the frontal eye field being an immature causal signaling hub in children. Control-theoretic analysis demonstrates that the saccade network is less controllable in children compared to adults.
Article
Multidisciplinary Sciences
Domenica Veniero, Joachim Gross, Stephanie Morand, Felix Duecker, Alexander T. Sack, Gregor Thut
Summary: The activation of the Frontal Eye Fields can shape visual cortex activity and perception through mechanisms of oscillatory realignment at the beta frequency.
NATURE COMMUNICATIONS
(2021)
Article
Clinical Neurology
Valentina Barone, Maria Carla Piastra, Johannes P. van Dijk, Gerhard H. Visser, Mariette H. J. A. Debeij-van Hall, Michel J. A. M. van Putten
Summary: This study investigates the differences in cognitive and eye movement processes during seizures in pediatric patients with absences. It reveals that the involvement of the right frontal eye field is higher in patients with impaired eye movements compared to those with preserved eye movements during seizures. This finding has clinical significance for assessing visual attention in epilepsy patients and providing personalized advice.
CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Naveen Sendhilnathan, Debaleena Basu, Michael E. Goldberg, Jeffrey D. Schall, Aditya Murthy
Summary: The study revealed unexpected differences in neural signatures for goal-directed versus non-goal-directed movements in a brain area selectively implicated in voluntary control, adding critical constraints to the way we think about saccade generation in the brain.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Alessio Fracasso, Antimo Buonocore, Ziad M. Hafed
Summary: Visual neural processing is distributed among various brain areas, exhibiting different functional specializations and spatial representational anisotropies. This study found that humans and monkeys perform better in identifying the orientation of visual stimuli in the upper visual field during peri-saccadic periods, contrary to the expected superiority of the lower visual field. These findings suggest that the peri-saccadic orientation identification performance is influenced by oculomotor rather than visual map spatial anisotropies.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Koorosh Mirpour, James W. Bisley
Summary: The lateral intraparietal area (LIP) provides a stable map integrating task rules and stimulus identity, while the frontal eye field (FEF) is consistently modulated by more complex information but integrates all information just before the saccade to make the final decision on where to move the eye.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Linjing Jiang, Hoi-Chung Leung
Summary: VSWM performance in 2D space was systematically mapped using memory-guided and visually guided saccade tasks. Memory-guided saccades showed increased unsystematic errors with target eccentricity and delay, indicating neurophysiological and functional factors contributing to errors in VSWM. These findings suggest limitations in VSWM representation, the influence of noise on memory maintenance, and potential independent mechanisms for spatial and temporal processing.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Tong Zhang, Tatiana Malevich, Matthias P. Baumann, Ziad M. Hafed
Summary: A systematic analysis reveals that the motor bursts in the superior colliculus (SC) neurons do not determine the kinematics of rapid eye movements. The spatial code and rate code of SC neurons exhibit dissociation, suggesting that saccade-related motor bursts in the SC do not necessarily dictate movement kinematics.
COMMUNICATIONS BIOLOGY
(2022)
Article
Neurosciences
Kaleb A. Lowe, Wolf Zinke, Joshua D. Cosman, Jeffrey D. Schall
Summary: This study investigated the neuronal spiking modulation patterns in the FEF and F2vr areas of macaque monkeys. The results showed differences in the variety of modulation patterns, proportions of visuomotor neuron types, and consistency of modulation patterns across tasks between FEF and F2vr.
Article
Neurosciences
J. Patrick Mayo, Amie R. DiTomasso, Marc A. Sommer, Matthew A. Smith
JOURNAL OF NEUROPHYSIOLOGY
(2015)
Article
Psychology
Hanna Oh, Jeffrey M. Beck, Pingping Zhu, Marc A. Sommer, Silvia Ferrari, Tobias Egner
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-LEARNING MEMORY AND COGNITION
(2016)
Article
Neurosciences
Valeria C. Caruso, Daniel S. Pages, Marc A. Sommer, Jennifer M. Groh
JOURNAL OF NEUROPHYSIOLOGY
(2016)
Review
Neurosciences
Hrishikesh M. Rao, J. Patrick Mayo, Marc A. Sommer
JOURNAL OF NEUROPHYSIOLOGY
(2016)
Article
Ophthalmology
Hrishikesh M. Rao, Zachary M. Abzug, Marc A. Sommer
Article
Mathematical & Computational Biology
Hrishikesh M. Rao, Juan San Juan, Fred Y. Shen, Jennifer E. Villa, Kimia S. Rafie, Marc A. Sommer
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
(2016)
Article
Neurosciences
Hanna Oh-Descher, Jeffrey M. Beck, Silvia Ferrari, Marc A. Sommer, Tobias Egner
Article
Neurosciences
Valeria C. Caruso, Daniel S. Pages, Marc A. Sommer, Jennifer M. Groh
JOURNAL OF NEUROPHYSIOLOGY
(2018)
Article
Psychology, Biological
Zachary M. Abzug, Marc A. Sommer
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION
(2018)
Article
Neurosciences
Anna S. Mitchell, S. Murray Sherman, Marc A. Sommer, Robert G. Mair, Robert P. Vertes, Yogita Chudasama
JOURNAL OF NEUROSCIENCE
(2014)
Article
Neurosciences
Jerel K. Mueller, Erinn M. Grigsby, Vincent Prevosto, Frank W. Petraglia, Hrishikesh Rao, Zhi-De Deng, Angel V. Peterchev, Marc A. Sommer, Tobias Egner, Michael L. Platt, Warren M. Grill
NATURE NEUROSCIENCE
(2014)
Article
Psychology, Multidisciplinary
Hrishikesh M. Rao, Rajan Khanna, David J. Zielinski, Yvonne Lu, Jillian M. Clements, Nicholas D. Potter, Marc A. Sommer, Regis Kopper, Lawrence G. Appelbaum
FRONTIERS IN PSYCHOLOGY
(2018)
Proceedings Paper
Engineering, Electrical & Electronic
David J. Zielinski, Hrishikesh M. Rao, Nicholas D. Potter, Marc A. Sommer, Lawrence G. Appelbaum, Regis Kopper
2016 IEEE SYMPOSIUM ON 3D USER INTERFACES (3DUI)
(2016)
Article
Behavioral Sciences
Ramanujan T. Raghavan, Vincent Prevosto, Marc A. Sommer
CURRENT OPINION IN BEHAVIORAL SCIENCES
(2016)
Proceedings Paper
Computer Science, Cybernetics
David J. Zielinski, Hrishikesh M. Rao, Mark A. Sommer, Regis Kopper
2015 IEEE VIRTUAL REALITY CONFERENCE (VR)
(2015)