Article
Neurosciences
Jack Jiaqi Zhang, Kenneth N. K. Fong
Summary: This study aimed to investigate the effect of priming iTBS with cTBS on sensorimotor oscillatory activities in healthy adults. The results showed that combining iTBS with cTBS had similar effects on enhancing movement-related ERD, with greater enhancement observed in the high mu band for the priming iTBS condition.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Neurosciences
Szu-Hung Lin, Chia-Hsiung Cheng, Ching-Yi Wu, Chien-Ting Liu, Chia-Ling Chen, Yu-Wei Hsieh
Summary: Mirror visual feedback (MVF) is shown to increase excitability in the primary motor cortex (M1) during asynchronous bimanual movement, while reducing functional connections between the visual cortex and brain regions associated with perceptuo-motor-attentional processes. This study provides a foundation for further research on the neural mechanisms of mirror illusion in motor control.
Article
Psychology, Biological
Marco Rizzo, Claudio Del Percio, Laura Petrini, Susanna Lopez, Lars Arendt-Nielsen, Claudio Babiloni
Summary: Mirror visual feedback (MVF) technique induces the illusion of bilateral synchronous movements during unilateral movements. An EEG study demonstrated that this illusion was related to alpha rhythm desynchronization in cortical areas during finger movements. The present study re-analyzed the data to localize the cortical sources of alpha rhythm during the anticipation and experience of the MVF-induced illusion. Results showed increased alpha rhythm sources in frontal-parietal areas during both anticipation and experience of the illusion, suggesting dynamic changes in these areas contribute to the illusory experience.
Article
Computer Science, Artificial Intelligence
Sergio Verduzco-Flores, William Dorrell, Erik De Schutter
Summary: This paper explores a neural control architecture that is both biologically plausible and capable of autonomous learning. It uses feedback controllers that learn to achieve a desired state by selecting the errors that drive them, employing a family of differential Hebbian learning rules. The architecture can control systems with monotonically or non-monotonically changing error responses through reinforcement learning. The use of feedback control simplifies the learning problem and allows for learning of more complex actions.
Article
Multidisciplinary Sciences
Shahabeddin Vahdat, Arjun Vivek Pendharkar, Terrance Chiang, Sean Harvey, Haruto Uchino, Zhijuan Cao, Anika Kim, ManKin Choy, Hansen Chen, Hyun Joo Lee, Michelle Y. Cheng, Jin Hyung Lee, Gary K. Steinberg
Summary: Poststroke optogenetic stimulations in mice can restore activation of ipsilesional corticothalamic and corticocortical circuits, which is correlated with functional recovery. Stimulation of the corticothalamic circuit alone is sufficient to improve functional recovery after stroke. These findings suggest early involvement of the corticothalamic circuit as a key mediator of poststroke recovery.
Article
Psychology, Biological
Marco Rizzo, Laura Petrini, Claudio Del Percio, Susanna Lopez, Lars Arendt-Nielsen, Claudio Babiloni
Summary: This study tested the hypothesis that using a mirror can induce the illusion of movement with the other hand, and found that this phenomenon is related to interactions among cerebral cortex, basal ganglia, and thalamus. The use of mirror resulted in prominent brain activity during unilateral right movements, possibly reflecting excitatory desynchronizing signals.
Article
Multidisciplinary Sciences
Akira Yamashita, Takenobu Murakami, Noriaki Hattori, Ichiro Miyai, Yoshikazu Ugawa
Summary: The study demonstrated that PCMS with supramaximal PNS intensity increased CMEP amplitude, and its facilitatory effect was greater than those of weaker PNS intensities for PCMS. Sham TMS with supramaximal PNS showed no changes in CMEP after intervention. The PNS intensity influences the magnitude of synaptic plasticity induction between CSTs and SMs at the spinal level, with supramaximal intensity being the most effective for inducing long-term potentiation-like effects.
Article
Engineering, Electrical & Electronic
Shunsuke Izuhara, Tomoaki Mashimo Toyohashi
Summary: This article introduces a miniature linear piezoelectric ultrasonic motor with a thin and hollow design, which can be used in autofocusing features of next-generation camera modules. The relationship between dimensions and preload is modeled to quantify the preload value and clarify the design methodology of the motor. After optimization and experimental evaluation, the motor provides thrust force suitable for quick response, meeting the requirement for autofocusing.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Neurosciences
Yongrong Wang, Shuai Feng, Rui Yang, Wensheng Hou, Xiaoying Wu, Lin Chen
Summary: This study aimed to investigate the learning-relative hemodynamic modulation of cortical plasticity induced by long-term motor training. The results showed that cortical hemodynamic activations exhibited an expansion-renormalization trend during continuous motor training, and the enhancement of functional connectivity may be maintained after amplitude renormalization. TMS findings suggested neural facilitations on the descending motor pathway after certain level of learning stages, and the learning could transfer to enhance performance in similar tasks.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Paolo Di Luzio, Luca Tarasi, Juha Silvanto, Alessio Avenanti, Vincenzo Romei
Summary: This study used ccPAS protocol to manipulate perceptual sensitivity and metacognitive ability in humans. The findings demonstrated a functional dissociation between these two cognitive processes, with different networks involved in each one.
Article
Biology
Junshi Lu, Lu Luo, Qian Wang, Fang Fang, Nihong Chen
Summary: The recall of learned temporal sequences through a visual cue is an important form of neural plasticity, observed in awake human visual cortex with neural reactivation in the downstream receptive field. After repeated exposure to a moving dot, a flash of the dot triggers neural reactivation in the receptive field along the motion path, with faster estimated traveling speed than real motion activation.
SCIENCE CHINA-LIFE SCIENCES
(2021)
Article
Clinical Neurology
Jifeng Rong, Li Ding, Li Xiong, Wen Zhang, Weining Wang, Meikui Deng, Yana Wang, Zhen Chen, Jie Jia
Summary: This study investigated the impact of mirror visual feedback combined with robot-assisted training on stroke patient recovery. The results showed that mirror visual feedback priming can enhance motor recovery, increase self-care abilities, and potentially improve grip strength. Additionally, mirror visual feedback priming may improve patient performance and engagement during robot-assisted training, which could influence the design and development of robotic systems.
FRONTIERS IN NEUROLOGY
(2021)
Article
Multidisciplinary Sciences
Kento Hirayama, Takayuki Koga, Toru Takahashi, Rieko Osu
Summary: The PPC plays a crucial role in hand choice tasks, with its left side activity significantly influencing hand selection. Transcranial direct current stimulation can alter PPC excitability, which in turn affects hand choice probability and reaction time. The findings suggest an asymmetry in PPC-mediated regulation of hand choice.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Tejapratap Bollu, Brendan S. Ito, Samuel C. Whitehead, Brian Kardon, James Redd, Mei Hong Liu, Jesse H. Goldberg
Summary: Precise tongue control is crucial for drinking, and corrective submovements are necessary after missing targets during mouse licking. The anterolateral motor cortex plays a key role in neural control of lingual kinematics, reflecting adjustments and errors during tongue movements.
Article
Neurosciences
Gokulraj T. Prabhakaran, Khaldoon O. Al-Nosairy, Claus Tempelmann, Markus Wagner, Hagen Thieme, Michael B. Hoffmann
Summary: The study found that in patients with advanced glaucoma and retinal lesions, the lesion projection zone showed positive responses during visual tasks and negative responses during passive viewing, which was not evident in healthy controls. Additionally, the trend in task-dependent LPZ responses being inversely related to visual field loss suggests the benefits of patient stratification strategies in future studies with larger sample sizes.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Yasuyuki Takamatsu, Satoko Koganemaru, Tatsunori Watanabe, Sumiya Shibata, Yoshihiro Yukawa, Masatoshi Minakuchi, Ryota Shimomura, Tatsuya Mima
Summary: This study investigates the effects of transcranial static magnetic stimulation (tSMS) on cortical excitability and interhemispheric inhibition between the left and right primary motor cortex (M1) in healthy subjects. The findings show a decrease in corticospinal excitability in the left M1 and an increase in the right M1 after tSMS, along with a reduction in interhemispheric inhibition from the left to the right M1.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Sumiya Shibata, Tatsunori Watanabe, Yoshihiro Yukawa, Masatoshi Minakuchi, Ryota Shimomura, Sachimori Ichimura, Hikari Kirimoto, Tatsuya Mima
Summary: Transcranial static magnetic stimulation (tSMS) over the left primary motor cortex (M1) for 20 min modulates local cortical activity and interregional functional coupling in the theta band, suggesting its potential role in inducing neural oscillations and neurophysiological effects in the frontal cortex.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Tatsunori Watanabe, Nami Kubo, Xiaoxiao Chen, Keisuke Yunoki, Takuya Matsumoto, Takayuki Kuwabara, Toru Sunagawa, Shota Date, Tatsuya Mima, Hikari Kirimoto
Summary: This pilot study investigated the effects of transcranial static magnetic field stimulation (tSMS) on inhibitory control when applied over the dorsolateral prefrontal cortex (DLPFC). The results showed that tSMS did not affect reaction time, suggesting the possibility that it may not be capable of modulating inhibitory control or that the cognitive load in the study was insufficient to detect any effects.
Article
Neurosciences
Tomoya Gyoda, Ippei Nojima, Su-Chuan Lin, Satoko Koganemaru, Tatsuya Mima, Shigeo Tanabe, Ying-Zu Huang
Summary: This study aimed to investigate the effect of GABA activity strengthening through real-time neurofeedback training on subsequent motor learning. The results showed that the NFT intervention led to enhanced GABA activity and suppressed online learning but not offline learning.
Article
Behavioral Sciences
Akari Ogawa, Satoko Koganemaru, Toshimitsu Takahashi, Yuu Takemura, Hiroshi Irisawa, Masao Matsuhashi, Tatsuya Mima, Takashi Mizushima, Kenji Kansaku
Summary: This study investigated the brain activity during volitional swallowing in two ALS patients. The results showed individual differences in cortical motor outputs during swallowing, suggesting the need for a personalized therapeutic approach using ERD for ALS patients with dysphagia.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Editorial Material
Behavioral Sciences
Yuichi Takeuchi, Qun Li, Takeshi Kawano, Jun Nagai, Tatsuya Mima
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Editorial Material
Clinical Neurology
Sumiya Shibata, Tatsunori Watanabe, Naofumi Otsuru, Hideaki Onishi, Tatsuya Mima
Article
Neurosciences
Atsushi Shima, Tomoaki Miyake, Kazuki Tanaka, Akari Ogawa, Erika Omae, Yui Nagamori, Yusuke Miyata, Koji Ohata, Takakuni Maki, Yumie Ono, Tatsuya Mima, Ryosuke Takahashi, Satoko Koganemaru
Summary: Closed-loop brain stimulation combined with robot-assisted training targeting the swing phase of gait can enhance the recovery of gait function in post-stroke patients. Short-term and long-term interventions showed significant improvements in gait speed, the Timed Up and Go test result, and muscle strength. Further studies with a larger number of patients are needed.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Engineering, Biomedical
Sumiya Shibata, Tatsunori Watanabe, Takuya Matsumoto, Keisuke Yunoki, Takayuki Horinouchi, Hikari Kirimoto, Jianxu Zhang, Hen Wang, Jinglong Wu, Hideaki Onishi, Tatsuya Mima
Summary: This study developed a novel transcranial static magnetic field stimulation (tSMS) system for non-invasive deep brain stimulation. The results showed that the system was able to generate a sufficient magnetic field for neuromodulation in deep brain areas. This stimulation method could potentially be used for brain function regulation therapy.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2022)
Letter
Clinical Neurology
Ryota Shimomura, Sumiya Shibata, Satoko Koganemaru, Masatoshi Minakuchi, Sachimori Ichimura, Akihiro Itoh, Katsumi Shimotake, Tatsuya Mima
Article
Neurosciences
Atsushi Shima, Kazuki Tanaka, Akari Ogawa, Erika Omae, Tomoaki Miyake, Yui Nagamori, Yusuke Miyata, Koji Ohata, Yumie Ono, Tatsuya Mima, Ryosuke Takahashi, Satoko Koganemaru
Summary: This article introduces a novel treatment approach for progressive supranuclear palsy (PSP) patients, which combines backward gait training with synchronized cerebellar transcranial alternating current stimulation (tACS). Through short-term and long-term interventions, it was found that synchronized stimulation significantly reduced postural instability and improved gait speed, balance function, and fall-related self-efficacy in daily life.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Ippei Nojima, Mitsuya Horiba, Kento Sahashi, Satoko Koganemaru, Satona Murakami, Kiminori Aoyama, Noriyuki Matsukawa, Yumie Ono, Tatsuya Mima, Yoshino Ueki
Summary: This study developed a closed-loop transcranial electrical stimulation (tES) intervention for Parkinsonian gait disturbances, which significantly improved gait speed, stride length, gait symmetry, and subjective feelings about freezing. This non-pharmacological and non-invasive treatment approach could be a breakthrough in restoring gait function in patients with Parkinson's disease and related disorders.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Neurosciences
Tatsunori Watanabe, Xiaoxiao Chen, Keisuke Yunoki, Takuya Matsumoto, Takayuki Horinouchi, Kanami Ito, Haruki Ishida, Toru Sunagawa, Tatsuya Mima, Hikari Kirimoto
Summary: The effects of transcranial static magnetic stimulation (tSMS) on cognitive performance and brain activity were investigated in relation to left and right dorsolateral prefrontal cortex (DLPFC) stimulation. Both left and right DLPFC stimulation impaired working memory performance to a similar extent, but had different effects on brain oscillatory responses. Left DLPFC stimulation increased event-related synchronization in the beta band, while right DLPFC stimulation did not show this effect.
Article
Multidisciplinary Sciences
Yoshihiro Yukawa, Sumiya Shibata, Satoko Koganemaru, Masatoshi Minakuchi, Ryota Shimomura, Kazuhito Nakamura, Tatsuya Mima
Summary: This study aimed to investigate the effects of low-frequency rTMS combined with OT on the motor function recovery of the affected upper limb in chronic stroke patients with severe hemiparesis. The results showed that patients with severe hemiparesis exhibited increased upper limb use, improved movement quality, and reduced spasticity after receiving rTMS combined with OT. Patients with mild hemiparesis showed significant improvements in FMA scores and manual dexterity, increased upper limb use and MEP, and reduced spasticity after the treatment.
Review
Clinical Neurology
Ippei Nojima, Hisato Sugata, Hiroki Takeuchi, Tatsuya Mima
Summary: This meta-analysis evaluated the effect sizes of clinical studies investigating the use of BCI-based rehabilitation interventions in restoring upper extremity function in post-stroke patients. The results suggest that BCI-based training is superior to conventional interventions for motor recovery of the upper limbs, with a focus on the effectiveness of sensorimotor rhythm algorithm in detecting brain activity. Further studies involving larger cohorts are needed to confirm these results due to high risk of bias and heterogeneity among the studies.
NEUROREHABILITATION AND NEURAL REPAIR
(2022)
