Article
Geriatrics & Gerontology
Lili Ji, Jinrong Wang, Baoqi Zhu, Xiaoxia Qiao, Yaru Jin, Huaxin Si, Wenyu Wang, Yanhui Bian, Cuili Wang
Summary: This study examined the mediating role of emotional regulation strategies in the relationship between frailty and depressive symptoms among older medical inpatients. The results showed that expressive suppression and rumination mediated the relationship, while cognitive reappraisal did not. The findings suggest that interventions targeting expressive suppression and rumination may be effective in reducing the detrimental effect of frailty on psychological wellbeing among older medical inpatients.
Article
Medicine, General & Internal
Daiki Aomura, Yosuke Yamada, Makoto Harada, Koji Hashimoto, Yuji Kamijo
Summary: The study found that admission to a window-side bed did not prevent delirium development in older patients in a general ward. There was no significant difference between the window group and non-window group in terms of delirium prevention.
FRONTIERS IN MEDICINE
(2021)
Article
Anesthesiology
Elena Ahrens, Tim M. Tartler, Aiman Suleiman, Luca J. Wachtendorf, Haobo Ma, Guanqing Chen, Samir M. Kendale, Peter Kienbaum, Balachundhar Subramaniam, Soeren Wagner, Maximilian S. Schaefer
Summary: This study investigated the association between intra-procedural hypoxaemia or hypocapnia and delirium after surgery. The results showed that both hypoxaemia and hypocapnia were associated with an increased risk of postoperative delirium, and this association was dependent on the duration and magnitude of the events. Therefore, maintaining normal gas exchange is important to prevent postoperative neurological disorders.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Geriatrics & Gerontology
Naoki Akazawa, Masaki Kishi, Toshikazu Hino, Ryota Tsuji, Kimiyuki Tamura, Akemi Hioka, Hideki Moriyama
Summary: This study investigated the effects of aging on intramuscular adipose tissue in older inpatients, finding that intramuscular adipose tissue increases with age and is higher in patients aged over 85 years compared to those aged 65-74 years.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Geriatrics & Gerontology
Janani Thillainadesan, Sarah J. Aitken, Sue R. Monaro, John S. Cullen, Richard Kerdic, Sarah N. Hilmer, Vasi Naganathan
Summary: This study evaluates the impact of a novel model of care called Geriatric Comanagement of Older Vascular surgery inpatients, showing a reduction in hospital-acquired geriatric syndromes and delirium after implementation, with more significant effects observed in frail patients.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Virginia Boccardi, Sara Ercolani, Rocco Serra, Valentina Bubba, Alessandro Piccolo, Michela Scamosci, Alfredo Villa, Carmelinda Ruggiero, Patrizia Mecocci
Summary: This study investigated the impact of hypomagnesemia on the incidence of delirium in acute geriatric settings. The results showed that patients with lower serum magnesium levels had a higher risk of delirium, highlighting the importance of monitoring magnesium concentration for clinical management.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Medicine, General & Internal
Xiao-Ming Zhang, Jing Jiao, Na Guo, Chen Zhu, Zhen Li, Dongmei Lv, Hui Wang, Jingfen Jin, Xianxiu Wen, Shengxiu Zhao, Xinjuan Wu, Tao Xu
Summary: This study aimed to investigate the association between cognitive impairment and 30-day mortality among Chinese in-patients. The findings show that patients with cognitive impairment had a 1.76-fold increased risk of 30-day mortality compared to those with normal cognitive function, and this association remained significant after adjusting for various factors.
FRONTIERS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Skadi Wilke, Edgar Steiger, Tanja L. Baerwolff, Justus F. Kleine, Ursula Mueller-Werdan, Adrian Rosada
Summary: This study aimed to describe the detailed clinical course of delirium and related cognitive functioning in geriatric patients in a non-postoperative setting and identify risk factors. The results showed that treatment of the acute medical condition resulted in a fast decrease in delirium severity, while cognitive functioning improved over time with persisting memory deficits.
Article
Geriatrics & Gerontology
Rainer Wirth, Christiane Nicola Klimek, Gero Lueg, Maryam Pourhassan, Louisa Maria Danielzik, Caroline Krueger, Ulrike Sonja Trampisch
Summary: This retrospective study found that cognitive changes frequently occur in geriatric patients during acute disease, independent of delirium. The term acute disease induced cognitive dysfunction (ADICD) is proposed for this phenomenon.
Article
Clinical Neurology
Ganesh M. Babulal, Yiqi Zhu, Catherine M. Roe, Darrell L. Hudson, Monique M. Williams, Samantha A. Murphy, Jason Doherty, Ann M. Johnson, Jean-Francois Trani
Summary: Baseline differences in depression and antidepressant use were observed among cognitively normal older adults in different ethnoracial groups, and depression was found to independently predict a faster progression to incident cognitive impairment across these groups.
ALZHEIMERS & DEMENTIA
(2022)
Article
Dermatology
Shreya Patel, Joshua B. Cadwell, Salma Ahsanuddin, W. Clark Lambert
Summary: Older adults with malignant melanoma have more comorbidities compared to younger patients, while younger patients are more likely to have obesity and coagulopathy. Despite older patients being more prone to urinary tract infections, they have lower risks of acute respiratory failure and venous thromboembolism compared to younger patients. Surprisingly, inpatient mortality rates did not significantly differ between younger and older patients.
DERMATOLOGIC THERAPY
(2021)
Article
Agriculture, Dairy & Animal Science
Rosalind Wrightson, Mariangela Albertini, Federica Pirrone, Kevin McPeake, Patrizia Piotti
Summary: Canine cognitive dysfunction syndrome (CCDS) is a neurodegenerative disorder in older dogs, similar to early stages of Alzheimer's disease in humans. A study using an online questionnaire found that dogs with more severe cognitive dysfunction also showed more signs of musculoskeletal and neurological problems, including pain and sensory decline. The study suggests that older dogs should be carefully screened for medical conditions, especially pain, sensory decline, and digestive and metabolic disorders, when cognitive dysfunction is suspected.
Article
Geriatrics & Gerontology
Bin Wang, Chuanlin Mu, Xinhui Tang, Fei Wang, Gaofeng Zhang, Jiahan Wang, Rui Dong, Xu Lin, Yanlin Bi
Summary: This study investigated the association between postoperative delirium (POD) and mild cognitive impairment (MCI) and found that amyloid pathology and tau protein might partially mediate the influence of MCI on POD.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Endocrinology & Metabolism
Natasha Anouschka Mueller, Nina Kaegi-Braun, Mirsada Durmisi, Carla Gressies, Pascal Tribolet, Zeno Stanga, Beat Mueller, Philipp Schuetz
Summary: During illness, the conversion of thyroxine (T4) to triiodothyronine (T3) is reduced, known as low T3 syndrome. This study aimed to investigate the prognostic role of low T3 syndrome in patients at nutritional risk, including mortality, clinical outcomes, and response to nutritional support.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Psychiatry
Jia-Hui Ma, Ning-Hao Huang, Tao Huang, Dong-Liang Mu
Summary: This study aimed to investigate the association between serum 25-hydroxyvitamin D levels and dementia, mild cognitive impairment (MCI), and delirium. The results showed that participants with higher 25(OH)D levels had a lower risk of dementia, MCI, and delirium compared to those with lower levels.
PSYCHIATRY RESEARCH
(2023)