Neuronal-Astrocyte Metabolic Interactions: Understanding the Transition Into Abnormal Astrocytoma Metabolism

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

(2010) Z. J. Reitman et al.   JNCI-Journal of the National Cancer Institute

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

(2010) C. V. Clower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A syngeneic glioma model to assess the impact of neural progenitor target cell age on tumor malignancy

(2009) Andrei M. Mikheev et al.   AGING CELL

The expression and significance of HIF-1α and GLUT-3 in glioma

(2009) Yang Liu et al.   BRAIN RESEARCH

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Mutant Metabolic Enzymes Are at the Origin of Gliomas

(2009) H. Yan et al.   CANCER RESEARCH

EGF receptor inhibitors in the treatment of glioblastoma multiform: Old clinical allies and newly emerging therapeutic concepts

(2009) Macoura Gadji et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glioblastoma multiforme: a review of therapeutic targets

(2009) Okezie O Kanu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Adult human brain cell culture for neuroscience research

(2009) Hannah M. Gibbons et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines

(2009) Hani J. Marcus et al.   JOURNAL OF NEURO-ONCOLOGY

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

(2009) Randy L. Jensen   JOURNAL OF NEURO-ONCOLOGY

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

CANCER: Puzzling Patterns of Predisposition

(2009) P. J. Pollard et al.   SCIENCE

Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1 

(2009) S. Zhao et al.   SCIENCE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Metabolic and Hemodynamic Events after Changes in Neuronal Activity: Current Hypotheses, Theoretical Predictions and in vivo NMR Experimental Findings

(2008) Silvia Mangia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE

Lactate promotes glioma migration by TGF-β2–dependent regulation of matrix metalloproteinase-2

(2008) Fusun Baumann et al.   NEURO-ONCOLOGY

Mitochondrial Lactate Dehydrogenase Is Involved in Oxidative-Energy Metabolism in Human Astrocytoma Cells (CCF-STTG1)

(2008) Joseph Lemire et al.   PLoS One

CD133 Is a Marker of Bioenergetic Stress in Human Glioma

(2008) Corinne E. Griguer et al.   PLoS One

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE