Activation of NOX2 by the Stimulation of Ionotropic and Metabotropic Glutamate Receptors Contributes to Glutamate Neurotoxicity In Vivo Through the Production of Reactive Oxygen Species and Calpain Activation

mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia

(2010) Kazutoshi Murotomi et al.   JOURNAL OF NEUROCHEMISTRY

Pathways involved in the generation of reactive oxygen and nitrogen species during glucose deprivation and its role on the death of cultured hippocampal neurons

(2010) B. Páramo et al.   NEUROSCIENCE

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein Kinase C-Dependent NAD(P)H Oxidase Activation Induced by Type 1 Diabetes in Renal Medullary Thick Ascending Limb

(2009) Jing Yang et al.   HYPERTENSION

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NMDA Receptor Activation Increases Free Radical Production through Nitric Oxide and NOX2

(2009) H. Girouard et al.   JOURNAL OF NEUROSCIENCE

NOX2 mediates apoptotic death induced by staurosporine but not by potassium deprivation in cerebellar granule neurons

(2009) Alicia Guemez-Gamboa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters

(2009) Ana María Estrada-Sánchez et al.   NEUROBIOLOGY OF DISEASE

Evidence Group I mGluR Drugs Modulate the Activation Profile of Lipopolysaccharide-Exposed Microglia in Culture

(2009) Mark C. Farso et al.   NEUROCHEMICAL RESEARCH

Selective vulnerability of brain regions to oxidative stress in a non-coma model of insulin-induced hypoglycemia

(2009) M.L. Haces et al.   NEUROSCIENCE

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease

(2008) Ana María Estrada Sánchez et al.   ARCHIVES OF MEDICAL RESEARCH

Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats

(2008) Cristiano R. Jesse et al.   BRAIN RESEARCH

Mild mitochondrial inhibition in vivo enhances glutamate-induced neuronal damage through calpain but not caspase activation: Role of ionotropic glutamate receptors

(2008) Perla Del Río et al.   EXPERIMENTAL NEUROLOGY

Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons

(2008) Angélica Coyoy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation

(2008) Y LI et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity

(2008) Kimberly R. Byrnes et al.   GLIA

Neuroprotective Effects of Tempol, a Catalytic Scavenger of Peroxynitrite-Derived Free Radicals, in a Mouse Traumatic Brain Injury Model

(2008) Ying Deng-Bryant et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

mGluR1 antagonist decreases tyrosine phosphorylation of NMDA receptor and attenuates infarct size after transient focal cerebral ischemia

(2008) Kazutoshi Murotomi et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2in cortical neurons

(2008) Phullara B. Shelat et al.   JOURNAL OF NEUROCHEMISTRY

Distinct roles of group I mGlu receptors in striatal function

(2008) P. Bonsi et al.   NEUROPHARMACOLOGY