Biomarkers in dementia: clinical utility and new directions

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration

(2013) Carole S. Scherling et al.   ANNALS OF NEUROLOGY

Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia

(2013) Maria Landqvist Waldö et al.   BMC Neurology

Inflammation in Alzheimer’s disease: insights from immunotherapy

(2013) Jonathan M. Schott et al.   BRAIN

A practical approach to diagnosing adult onset leukodystrophies

(2013) R. M. Ahmed et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical utility of dopamine transporter single photon emission CT (DaT-SPECT) with (123I) ioflupane in diagnosis of parkinsonian syndromes

(2013) Nin Bajaj et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration

(2013) C. T. McMillan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation

(2013) M. Suarez-Calvet et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

TDP-43 frontotemporal lobar degeneration and autoimmune disease

(2013) Z. A. Miller et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

An algorithmic approach to structural imaging in dementia

(2013) L. Harper et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The Identification of New Biomarkers for Identifying and Monitoring Kidney Disease and Their Translation into a Rapid Mass Spectrometry-Based Test: Evidence of Presymptomatic Kidney Disease in Pediatric Fabry and Type-I Diabetic Patients

(2013) Victoria Manwaring et al.   JOURNAL OF PROTEOME RESEARCH

Biomarker Modelling of Early Molecular Changes in Alzheimer’s Disease

(2013) Ross W. Paterson et al.   Molecular Diagnosis & Therapy

Fluid biomarkers in Alzheimer’s disease – current concepts

(2013) Christoffer Rosén et al.   Molecular Neurodegeneration

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

CSF biomarker changes precede symptom onset of mild cognitive impairment

(2013) A. Moghekar et al.   NEUROLOGY

Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP

(2013) W. T. Hu et al.   NEUROLOGY

Molecular nexopathies: a new paradigm of neurodegenerative disease

(2013) Jason D. Warren et al.   TRENDS IN NEUROSCIENCES

Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease

(2013) Gaël Chételat et al.   NeuroImage-Clinical

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

(2012) James D. Doecke   ARCHIVES OF NEUROLOGY

Determining cut-points for Alzheimer’s disease biomarkers: statistical issues, methods and challenges

(2012) Jonathan W Bartlett et al.   Biomarkers in Medicine

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics

(2012) J. L. Whitwell et al.   BRAIN

Recent Advances in the Imaging of Frontotemporal Dementia

(2012) Jennifer L. Whitwell et al.   Current Neurology and Neuroscience Reports

Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy

(2012) Luke A. Massey et al.   MOVEMENT DISORDERS

CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings

(2012) T. T. Seppala et al.   NEUROLOGY

Preclinical studies of potential amyloid binding PET/SPECT ligands in Alzheimer's disease

(2012) Marie M. Svedberg et al.   NUCLEAR MEDICINE AND BIOLOGY

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

(2011) J. D. Rohrer et al.   BRAIN

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

(2011) Katya Rascovsky et al.   BRAIN

Primary Progressive Aphasia-Defining Genetic and Pathological Subtypes

(2011) J. D. Rohrer et al.   Current Alzheimer Research

Biomarkers in dementia with Lewy bodies: a review

(2011) Namrta Sinha et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

(2011) Christopher M. Clark   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Behavioral Variant Frontotemporal Dementia with Corticobasal Degeneration Pathology: Phenotypic Comparison to bvFTD with Pick’s Disease

(2011) Katherine P. Rankin et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum

(2011) Andreas Charidimou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Classification of primary progressive aphasia and its variants

(2011) M. L. Gorno-Tempini et al.   NEUROLOGY

Real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   Prion

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer’s disease

(2010) Juan Zhou et al.   BRAIN

Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease

(2010) Annika Thorsell et al.   BRAIN RESEARCH

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

(2010) H. Seelaar et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The diagnosis of young-onset dementia

(2010) Martin N Rossor et al.   LANCET NEUROLOGY

The clinical use of structural MRI in Alzheimer disease

(2010) Giovanni B. Frisoni et al.   Nature Reviews Neurology

Primary progressive aphasia: clinicopathological correlations

(2010) Murray Grossman   Nature Reviews Neurology

Measuring disease progression in frontotemporal lobar degeneration: A clinical and MRI study

(2010) E. Gordon et al.   NEUROLOGY

Serum biomarker for progranulin-associated frontotemporal lobar degeneration

(2009) Kristel Sleegers et al.   ANNALS OF NEUROLOGY

Combined magnetic resonance imaging and positron emission tomography brain imaging in behavioural variant frontotemporal degeneration: refining the clinical phenotype

(2009) C. M. Kipps et al.   BRAIN

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Voxel-based morphometry patterns of atrophy in FTLD with mutations in MAPT or PGRN

(2009) J. L. Whitwell et al.   NEUROLOGY

Distinct patterns of brain activity in young carriers of the APOE- 4 allele

(2009) N. Filippini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

(2008) Takashi Kasai et al.   ACTA NEUROPATHOLOGICA

TDP-43 in Cerebrospinal Fluid of Patients With Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

(2008) Petra Steinacker et al.   ARCHIVES OF NEUROLOGY

Frontal Paralimbic Network Atrophy in Very Mild Behavioral Variant Frontotemporal Dementia

(2008) William W. Seeley et al.   ARCHIVES OF NEUROLOGY

Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis

(2008) E. J. Burton et al.   BRAIN

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

(2008) Brit Mollenhauer et al.   EXPERIMENTAL NEUROLOGY

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration

(2008) R. Ghidoni et al.   NEUROLOGY

Imaging amyloid deposition in Lewy body diseases

(2008) S. N. Gomperts et al.   NEUROLOGY

Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease

(2008) R. Duara et al.   NEUROLOGY

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

(2007) Miroslaw Brys et al.   NEUROBIOLOGY OF AGING