Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions

Cerebrospinal fluid lysosomal enzymes and alpha-synuclein in Parkinson's disease

(2014) Lucilla Parnetti et al.   MOVEMENT DISORDERS

Changes in endolysosomal enzyme activities in cerebrospinal fluid of patients with Parkinson's disease

(2013) Karin D. van Dijk et al.   MOVEMENT DISORDERS

Cerebrospinal fluid biomarkers in Parkinson disease

(2013) Lucilla Parnetti et al.   Nature Reviews Neurology

Combined dementia-risk biomarkers in Parkinson's disease: A prospective longitudinal study

(2013) Yaroslau Compta et al.   PARKINSONISM & RELATED DISORDERS

Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy

(2013) Malin Wennström et al.   PLoS One

Binding of the Radioligand SIL23 to α-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging Agent

(2013) Devika P. Bagchi et al.   PLoS One

Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease

(2013) Jere E. Meredith Jr. et al.   PLoS One

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau181, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease

(2013) Ju-Hee Kang   JAMA Neurology

Cerebrospinal Fluid Biomarker Candidates for Parkinsonian Disorders

(2013) Radu Constantinescu et al.   Frontiers in Neurology

Serum and cerebrospinal fluid urate levels in synucleinopathies versus tauopathies

(2012) R. Constantinescu et al.   ACTA NEUROLOGICA SCANDINAVICA

Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders

(2012) Sara Hall et al.   ARCHIVES OF NEUROLOGY

Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson’s disease and other synucleinopathies

(2012) David S. Goldstein et al.   BRAIN

iTRAQ and multiple reaction monitoring as proteomic tools for biomarker search in cerebrospinal fluid of patients with Parkinson's disease dementia

(2012) Stefan Lehnert et al.   EXPERIMENTAL NEUROLOGY

Elevated Levels of α-Synuclein Oligomer in the Cerebrospinal Fluid of Drug-Naïve Patients with Parkinson's Disease

(2012) Min Jeong Park et al.   Journal of Clinical Neurology

Development and assessment of sensitive immuno-PCR assays for the quantification of cerebrospinal fluid three- and four-repeat tau isoforms in tauopathies

(2012) Connie Luk et al.   JOURNAL OF NEUROCHEMISTRY

Cerebrospinal fluid proteomic patterns discriminate Parkinson's disease and multiple system atrophy

(2012) Noriko Ishigami et al.   MOVEMENT DISORDERS

Applying bioinformatics to proteomics: Is machine learning the answer to biomarker discovery for PD and MSA?

(2012) Hayley A. Mattison et al.   MOVEMENT DISORDERS

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

(2012) Brit Mollenhauer et al.   NEUROSCIENCE LETTERS

The DJ-1 concentration in cerebrospinal fluid does not differentiate among parkinsonian syndromes

(2012) Lisette Salvesen et al.   PARKINSONISM & RELATED DISORDERS

Differential Sialylation of Serpin A1 in the Early Diagnosis of Parkinson’s Disease Dementia

(2012) Sarah Jesse et al.   PLoS One

Phosphorylated  -Synuclein in Parkinson's Disease

(2012) Y. Wang et al.   Science Translational Medicine

Alpha-synuclein in the Cerebrospinal Fluid Differentiates Synucleinopathies (Parkinson Disease, Dementia With Lewy Bodies, Multiple System Atrophy) From Alzheimer Disease

(2011) Fuyuki Tateno et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Complement 3 and Factor H in Human Cerebrospinal Fluid in Parkinson's Disease, Alzheimer's Disease, and Multiple-System Atrophy

(2011) Yu Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease

(2011) Peter LeWitt et al.   BRAIN RESEARCH

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

CSF levels of oligomeric alpha-synuclein and beta-amyloid as biomarkers for neurodegenerative disease

(2011) Michael R. Sierks et al.   Integrative Biology

Induction of Intracellular Tau Aggregation Is Promoted by  -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

(2011) E. A. Waxman et al.   JOURNAL OF NEUROSCIENCE

CSF α-synuclein, tau, and amyloid β in Parkinson's disease – Authors' reply

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Pathological roles of α-synuclein in neurological disorders

(2011) Kostas Vekrellis et al.   LANCET NEUROLOGY

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Cerebrospinal fluid Tau/α-synuclein ratio in Parkinson's disease and degenerative dementias

(2011) Lucilla Parnetti et al.   MOVEMENT DISORDERS

Corticobasal degeneration: a pathologically distinct 4R tauopathy

(2011) Naomi Kouri et al.   Nature Reviews Neurology

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

(2011) P.G. Foulds et al.   NEUROBIOLOGY OF DISEASE

Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method

(2011) Annika Öhrfelt et al.   NEUROCHEMICAL RESEARCH

Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy

(2011) H. B. Kuiperij et al.   NEUROLOGY

Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort

(2011) N. S. M. Schoonenboom et al.   NEUROLOGY

Amyloid-related biomarkers and axonal damage proteins in parkinsonian syndromes

(2011) Sara Bech et al.   PARKINSONISM & RELATED DISORDERS

Biomarkers of Parkinson's disease and Dementia with Lewy bodies

(2011) Claire Henchcliffe et al.   PROGRESS IN NEUROBIOLOGY

The Parkinson Progression Marker Initiative (PPMI)

(2011) Kenneth Marek et al.   PROGRESS IN NEUROBIOLOGY

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

(2010) Min Shi et al.   ANNALS OF NEUROLOGY

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Disentangling the Role of the Tau Gene Locus in Sporadic Tauopathies

(2010) J. Vandrovcova et al.   Current Alzheimer Research

Using ‘omics’ to define pathogenesis and biomarkers of Parkinson’s disease

(2010) W Michael Caudle et al.   Expert Review of Neurotherapeutics

The cognitive profile and CSF biomarkers in dementia with Lewy bodies and Parkinson's disease dementia

(2010) M. Andersson et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

CSF amyloid-  and tau proteins, and cognitive performance, in early and untreated Parkinson's Disease: the Norwegian ParkWest study

(2010) G. Alves et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Biomarker promise for Parkinson's disease

(2010) The Lancet Neurology   LANCET NEUROLOGY

DJ-1, PINK1, and their effects on mitochondrial pathways

(2010) Mark R. Cookson   MOVEMENT DISORDERS

Differential pattern of brain-specific CSF proteins tau and amyloid-beta in Parkinsonian syndromes

(2010) Sigurd D. Süssmuth et al.   MOVEMENT DISORDERS

CSF Aβ42and tau in Parkinson's disease with cognitive impairment

(2010) Thomas J. Montine et al.   MOVEMENT DISORDERS

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Diagnosis of progressive supranuclear palsy: can measurement of tau forms help?

(2010) H. Bea Kuiperij et al.   NEUROBIOLOGY OF AGING

Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2010) T. Tokuda et al.   NEUROLOGY

CSF amyloid   1-42 predicts cognitive decline in Parkinson disease

(2010) A. Siderowf et al.   NEUROLOGY

Genetic Analysis of Pathways to Parkinson Disease

(2010) John Hardy   NEURON

Proteomic profiling of cerebrospinal fluid in parkinsonian disorders

(2010) Radu Constantinescu et al.   PARKINSONISM & RELATED DISORDERS

The genetics of Parkinson's syndromes: a critical review

(2009) John Hardy et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cerebrospinal tau, phospho-tau, and beta-amyloid and neuropsychological functions in Parkinson's disease

(2009) Yaroslau Compta et al.   MOVEMENT DISORDERS

Biological fluid biomarkers in neurodegenerative parkinsonism

(2009) Michael Eller et al.   Nature Reviews Neurology

Cerebrospinal fluid β-glucocerebrosidase activity is reduced in Dementia with Lewy Bodies

(2009) L. Parnetti et al.   NEUROBIOLOGY OF DISEASE

8-OHdG in Cerebrospinal Fluid as a Marker of Oxidative Stress in Various Neurodegenerative Diseases

(2009) K. Gmitterová et al.   Neurodegenerative Diseases

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Consecutive analyses of cerebrospinal fluid axonal and glial markers in Parkinson's disease and atypical parkinsonian disorders

(2009) Radu Constantinescu et al.   PARKINSONISM & RELATED DISORDERS

Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease

(2008) Kurt A. Jellinger et al.   ACTA NEUROPATHOLOGICA

The progression of pathology in longitudinally followed patients with Parkinson’s disease

(2008) Glenda Halliday et al.   ACTA NEUROPATHOLOGICA

CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases

(2008) Jing Zhang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Cerebrospinal Fluid Biomarkers in Parkinson's Disease with Dementia and Dementia with Lewy Bodies

(2008) Lucilla Parnetti et al.   BIOLOGICAL PSYCHIATRY

CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer's disease

(2008) Moeko Noguchi-Shinohara et al.   BRAIN RESEARCH

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

(2008) Brit Mollenhauer et al.   EXPERIMENTAL NEUROLOGY

Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy

(2008) B. Borroni et al.   NEUROLOGY

Cerebrospinal fluid α-synuclein in neurodegenerative disorders—A marker of synapse loss?

(2008) Annika Öhrfelt et al.   NEUROSCIENCE LETTERS

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One