Progress in Alzheimer’s disease research in the last year

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model

(2012) Soon-Tae Lee et al.   ANNALS OF NEUROLOGY

Cerebrospinal Fluid Levels ofβ-Amyloid 1-42, but Not of Tau, Are Fully Changed Already 5 to 10 Years Before the Onset of Alzheimer Dementia

(2012) Peder Buchhave   ARCHIVES OF GENERAL PSYCHIATRY

Plasma Biomarkers Associated With the Apolipoprotein E Genotype and Alzheimer Disease

(2012) Holly D. Soares   ARCHIVES OF NEUROLOGY

Antioxidants for Alzheimer Disease

(2012) Douglas R. Galasko et al.   ARCHIVES OF NEUROLOGY

Proteomic Changes in Cerebrospinal Fluid of Presymptomatic and Affected Persons Carrying Familial Alzheimer Disease Mutations

(2012) John M. Ringman   ARCHIVES OF NEUROLOGY

Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study

(2012) Daniel H. J. Davis et al.   BRAIN

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

(2012) Fredrik Jeppsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of clinical characteristics between familial and non-familial early onset Alzheimer’s disease

(2012) Aditi Joshi et al.   JOURNAL OF NEUROLOGY

Stereotypic behaviors in degenerative dementias

(2012) S. Prioni et al.   JOURNAL OF NEUROLOGY

Region-Specific Hierarchy between Atrophy, Hypometabolism, and  -Amyloid (A ) Load in Alzheimer's Disease Dementia

(2012) R. La Joie et al.   JOURNAL OF NEUROSCIENCE

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

(2012) Eric M Reiman et al.   LANCET NEUROLOGY

Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study

(2012) Bengt Winblad et al.   LANCET NEUROLOGY

Injury markers predict time to dementia in subjects with MCI and amyloid pathology

(2012) I. A. van Rossum et al.   NEUROLOGY

Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease

(2012) M. Watabe-Rudolph et al.   NEUROLOGY

Age and diagnostic performance of Alzheimer disease CSF biomarkers

(2012) N. Mattsson et al.   NEUROLOGY

Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice

(2012) S.C.F. Marques et al.   NEUROSCIENCE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Executive dysfunction in frontotemporal dementia is related to abnormalities in frontal white matter tracts

(2011) M. C. Tartaglia et al.   JOURNAL OF NEUROLOGY

Revising the definition of Alzheimer's disease: a new lexicon

(2010) Bruno Dubois et al.   LANCET NEUROLOGY