K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression

Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide

(2017) Asa Hatami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

(2017) Marta Querol-Vilaseca et al.   Journal of Neuroinflammation

CHI3L1 and CHI3L2 overexpression in motor cortex and spinal cord of sALS patients

(2017) C. Sanfilippo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

(2017) Reisuke H. Takahashi et al.   PATHOLOGY INTERNATIONAL

An Overview on the Role of α -Synuclein in Experimental Models of Parkinson’s Disease from Pathogenesis to Therapeutics

(2016) Hayate Javed et al.   CNS & Neurological Disorders-Drug Targets

Time-Dependent Increase of Chitinase1 in APP/PS1 Double Transgenic Mice

(2016) Qian Xiao et al.   NEUROCHEMICAL RESEARCH

Deletion of Nuclear Factor kappa B p50 Subunit Decreases Inflammatory Response and Mildly Protects Neurons from Transient Forebrain Ischemia-induced Damage

(2016) Taisia Rolova et al.   Aging and Disease

Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis

(2015) G Hinsinger et al.   Multiple Sclerosis Journal

Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease

(2015) Daniel Alcolea et al.   NEUROBIOLOGY OF AGING

The Inflammatory Marker YKL-40 Is Elevated in Cerebrospinal Fluid from Patients with Alzheimer’s but Not Parkinson’s Disease or Dementia with Lewy Bodies

(2015) Malin Wennström et al.   PLoS One

Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis

(2015) G Hinsinger et al.   Multiple Sclerosis Journal

Chitinase 3-like 1 Synergistically Activates IL6-mediated STAT3 Phosphorylation in Intestinal Epithelial Cells in Murine Models of Infectious Colitis

(2014) Hoa T. Tran et al.   INFLAMMATORY BOWEL DISEASES

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding properties

(2012) Marianne Schimpl et al.   BIOCHEMICAL JOURNAL

Chitinase 3-Like-1 Expression in Colonic Epithelial Cells as a Potentially Novel Marker for Colitis-Associated Neoplasia

(2011) Chun-Chuan Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease

(2011) Chia-Hsiung Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseases

(2010) Dafna Bonneh-Barkay et al.   Journal of Neuroinflammation

Prostaglandin H synthase-2 gene regulation in the amnion at labour: histone acetylation and nuclear factor kappa B binding to the promoter in vivo

(2008) C.M. Mitchell et al.   MOLECULAR HUMAN REPRODUCTION