Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation

FTY720 Improves Functional Recovery after Spinal Cord Injury by Primarily Nonimmunomodulatory Mechanisms

(2012) Yusuke Norimatsu et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of a Sphingosine 1-Phosphate Receptor Antagonist Prodrug

(2011) P. C. Kennedy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Development of small-molecule inhibitors of sphingosine-1-phosphate signaling

(2011) Yvette Edmonds et al.   PHARMACOLOGY & THERAPEUTICS

Differential responses of human microglia and blood-derived myeloid cells to FTY720

(2010) Bryce A. Durafourt et al.   JOURNAL OF NEUROIMMUNOLOGY

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

(2010) J. W. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

(2009) Florian Mullershausen et al.   Nature Chemical Biology