Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

Dopaminergic neuroprotection of hormonal replacement therapy in young and aged menopausal rats: role of the brain angiotensin system

(2011) A. I. Rodriguez-Perez et al.   BRAIN

Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade

(2011) W Michael Zawada et al.   Journal of Neuroinflammation

Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model

(2011) A.R. Carta et al.   NEUROSCIENCE

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system

(2010) L. Füchtbauer et al.   BRAIN BEHAVIOR AND IMMUNITY

Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia

(2010) Yukiko Kasahara et al.   BRAIN RESEARCH

Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria?

(2010) E. M. V. de Cavanagh et al.   CARDIOVASCULAR RESEARCH

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Angiotensin II sustains brain inflammation in mice via TGF-β

(2010) Tobias V. Lanz et al.   JOURNAL OF CLINICAL INVESTIGATION

Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-γ activation in diabetic mice

(2010) Jun Iwanami et al.   JOURNAL OF HYPERTENSION

Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration

(2010) Begoña Villar-Cheda et al.   NEUROBIOLOGY OF AGING

Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells

(2009) João Wosniak et al.   ANTIOXIDANTS & REDOX SIGNALING

Long term treatment with ACE inhibitor enalapril decreases body weight gain and increases life span in rats

(2009) Edson Lucas Santos et al.   BIOCHEMICAL PHARMACOLOGY

The Role of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in Alzheimer’s Disease

(2009) Qingguang Jiang et al.   CNS DRUGS

PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson’s disease

(2009) Nicoletta Schintu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cognitive Deficit in Amyloid-β–Injected Mice Was Improved by Pretreatment With a Low Dose of Telmisartan Partly Because of Peroxisome Proliferator-Activated Receptor-γ Activation

(2009) Kana Tsukuda et al.   HYPERTENSION

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

Deletion of angiotensin II type I receptor reduces hepatic steatosis

(2009) Yoshitaka Nabeshima et al.   JOURNAL OF HEPATOLOGY

Peroxisome proliferator-activated receptor α activation attenuated angiotensin type 1-mediated but enhanced angiotensin type 2-mediated hemodynamic effects to angiotensin II in the rat

(2009) Tina Banks et al.   JOURNAL OF HYPERTENSION

The inflammatory response in the MPTP model of Parkinson’s disease is mediated by brain angiotensin: relevance to progression of the disease

(2009) Belen Joglar et al.   JOURNAL OF NEUROCHEMISTRY

PPARγ agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway

(2009) Yuanyuan Ji et al.   LABORATORY INVESTIGATION

Cerebroprotective action of telmisartan by inhibition of macrophages/microglia expressing HMGB1 via a peroxisome proliferator-activated receptor γ-dependent mechanism

(2009) Tamami Haraguchi et al.   NEUROSCIENCE LETTERS

The Mitochondrial ATP-Sensitive Potassium Channel Blocker 5-Hydroxydecanoate Inhibits Toxicity of 6-Hydroxydopamine on Dopaminergic Neurons

(2009) J. Rodriguez-Pallares et al.   NEUROTOXICITY RESEARCH

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

(2009) J. Stegbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity

(2009) M. Platten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

PPARγ agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms

(2008) Jae-Hyuk Yi et al.   BRAIN RESEARCH

Angiotensin inhibition stimulates PPARγ and the release of visfatin

(2008) A. Storka et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Nuclear Hormone Receptors as Regulators of the Renin-Angiotensin-Aldosterone System

(2008) Irma Kuipers et al.   HYPERTENSION

Angiotensin II Type 1 (AT1) Receptor Deficiency Halts the Progression of Age-Related Atherosclerosis in Hypercholesterolemia: Molecular Link between the AT1 Receptor and Hypercholesterolemia

(2008) Seiji UMEMOTO   HYPERTENSION RESEARCH

Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS

(2008) J. Rodriguez-Pallares et al.   NEUROBIOLOGY OF DISEASE

AT2 receptors: Functional relevance in cardiovascular disease

(2008) Emma S. Jones et al.   PHARMACOLOGY & THERAPEUTICS

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS

Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain

(2007) David J. Loane et al.   NEUROBIOLOGY OF AGING