Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB

Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation

(2014) H. Shen et al.   JOURNAL OF IMMUNOLOGY

Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina

(2011) Folami Lamoke et al.   EXPERIMENTAL EYE RESEARCH

Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10

(2011) Yun Sang Lee et al.   IMMUNOLOGY

Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina

(2011) Viswanathan Sivakumar et al.   JOURNAL OF PATHOLOGY

Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation

(2010) Yanji Cui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

(2010) Robert Field et al.   BRAIN BEHAVIOR AND IMMUNITY

A meta-analysis of the efficacy and tolerability of interferon-β in multiple sclerosis, overall and by drug and disease type

(2010) Shekoufeh Nikfar et al.   CLINICAL THERAPEUTICS

HMBG1 Mediates Ischemia—Reperfusion Injury by TRIF-Adaptor Independent Toll-Like Receptor 4 Signaling

(2010) Qing-Wu Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Double-Stranded RNA Induces Shedding of the 34-kDa Soluble TNFR1 from Human Airway Epithelial Cells via TLR3-TRIF-RIP1-Dependent Signaling: Roles for Dual Oxidase 2- and Caspase-Dependent Pathways

(2010) M. Yu et al.   JOURNAL OF IMMUNOLOGY

IFN -1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum

(2010) J. Shimizu et al.   NEUROLOGY

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells

(2009) A Weber et al.   CELL DEATH AND DIFFERENTIATION

Therapie von Sehnerverkrankungen – der aktuelle Stand

(2009) W. Lagrèze   KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways

(2009) Barbara Lorber et al.   NATURE NEUROSCIENCE

Oncomodulin links inflammation to optic nerve regeneration

(2009) Y. Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE

The Optic Nerve

(2009) John Selhorst et al.   SEMINARS IN NEUROLOGY

Toll-like receptor 4 restricts retinal progenitor cell proliferation

(2008) Ravid Shechter et al.   JOURNAL OF CELL BIOLOGY

Production and functions of IL-17 in microglia

(2008) Jun Kawanokuchi et al.   JOURNAL OF NEUROIMMUNOLOGY

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE