Secreted phospholipase A2-IIA-induced a phenotype of activated microglia in BV-2 cells requires epidermal growth factor receptor transactivation and proHB-EGF shedding

Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia

(2011) Wenwen Sheng et al.   Journal of Neuroinflammation

Forebrain specific heparin-binding epidermal growth factor-like growth factor knockout mice show exacerbated ischemia and reperfusion injury

(2011) A. Oyagi et al.   NEUROSCIENCE

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer link

(2010) M. Hernandez et al.   NEURO-ONCOLOGY

Valproic acid enhances microglial phagocytosis of amyloid-β1–42

(2010) A.M. Smith et al.   NEUROSCIENCE

Cerebrospinal Fluid Secretory Ca2+-Dependent Phospholipase A2 Activity Is Increased in Alzheimer Disease

(2009) S. Chalbot et al.   CLINICAL CHEMISTRY

Differential expression of sPLA2following spinal cord injury and a functional role for sPLA2-IIA in mediating oligodendrocyte death

(2009) W. Lee Titsworth et al.   GLIA

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR

(2009) Amalia Trousson et al.   JOURNAL OF NEUROCHEMISTRY

Secreted phospholipase A2-IIA modulates key regulators of proliferation on astrocytoma cells

(2009) Rubén Martín et al.   JOURNAL OF NEUROCHEMISTRY

The Rheb-mTOR Pathway Is Upregulated in Reactive Astrocytes of the Injured Spinal Cord

(2009) S. Codeluppi et al.   JOURNAL OF NEUROSCIENCE

Group X Phospholipase A2 Stimulates the Proliferation of Colon Cancer Cells by Producing Various Lipid Mediators

(2009) F. Surrel et al.   MOLECULAR PHARMACOLOGY

Human group III secreted phospholipase A2promotes neuronal outgrowth and survival

(2008) Seiko Masuda et al.   BIOCHEMICAL JOURNAL

PKC-δ/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE2 production in rat vascular smooth muscle cells

(2008) Hsi-Lung Hsieh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Secreted phospholipase A2 type IIA as a mediator connecting innate and adaptive immunity: new role in atherosclerosis

(2008) E. Ibeas et al.   CARDIOVASCULAR RESEARCH

Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner

(2008) Jun Saegusa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter

(2008) Yuta Ishizuka et al.   JOURNAL OF NEUROCHEMISTRY

Intranasal HB-EGF administration favors adult SVZ cell mobilization to demyelinated lesions in mouse corpus callosum

(2007) Cristina Cantarella et al.   Developmental Neurobiology