Tetherin and Its Viral Antagonists

Neither ritonavir nor darunavir affect cell surface expression of tetherin or Vpu-mediated tetherin down-modulation

(2010) Björn D Kuhl et al.   AIDS

Structural Basis of HIV-1 Tethering to Membranes by the BST-2/Tetherin Ectodomain

(2010) Andreas Hinz et al.   Cell Host & Microbe

Viral tricks to grid-lock the type I interferon system

(2010) Gijs A Versteeg et al.   CURRENT OPINION IN MICROBIOLOGY

The interface between the innate interferon response and expression of host retroviral restriction factors

(2010) Renée N. Douville et al.   CYTOKINE

Small Molecular Compounds Inhibit HIV-1 Replication through Specifically Stabilizing APOBEC3G

(2010) Shan Cen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BST-2 Diminishes HIV-1 Infectivity

(2010) J. Zhang et al.   JOURNAL OF VIROLOGY

Ebola Virus Glycoprotein Counteracts BST-2/Tetherin Restriction in a Sequence-Independent Manner That Does Not Require Tetherin Surface Removal

(2010) L. A. Lopez et al.   JOURNAL OF VIROLOGY

CD317/Tetherin Is Enriched in the HIV-1 Envelope and Downregulated from the Plasma Membrane upon Virus Infection

(2010) A. Habermann et al.   JOURNAL OF VIROLOGY

Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu

(2010) A. A. Tokarev et al.   JOURNAL OF VIROLOGY

Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein

(2010) R. Vigan et al.   JOURNAL OF VIROLOGY

Cell-Cell Spread of Human Immunodeficiency Virus Type 1 Overcomes Tetherin/BST-2-Mediated Restriction in T cells

(2010) C. Jolly et al.   JOURNAL OF VIROLOGY

Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

(2010) E. S. Lim et al.   JOURNAL OF VIROLOGY

Structural insight into the mechanisms of enveloped virus tethering by tetherin

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations

(2010) H. L. Schubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-tetherin activities in Vpu-expressing primate lentiviruses

(2010) Su Yang et al.   Retrovirology

HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment

(2010) Heiko Hauser et al.   Retrovirology

The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

(2010) Claire Pardieu et al.   PLoS Pathogens

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

(2010) Mathieu Dubé et al.   PLoS Pathogens

Direct Restriction of Virus Release and Incorporation of the Interferon-Induced Protein BST-2 into HIV-1 Particles

(2010) Kathleen Fitzpatrick et al.   PLoS Pathogens

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

(2010) Nicoletta Casartelli et al.   PLoS Pathogens

Antiviral Efficacy of the Novel Compound BIT225 against HIV-1 Release from Human Macrophages

(2009) G. Khoury et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

HIV-1 Antagonism of CD317 Is Species Specific and Involves Vpu-Mediated Proteasomal Degradation of the Restriction Factor

(2009) Christine Goffinet et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes

(2009) Yukie Iwabu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin

(2009) Naoko Masuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A CD317/tetherin–RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells

(2009) Ruth Rollason et al.   JOURNAL OF CELL BIOLOGY

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

(2009) Wei Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu

(2009) L. Rong et al.   JOURNAL OF VIROLOGY

Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein

(2009) A. Le Tortorec et al.   JOURNAL OF VIROLOGY

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

(2009) M. Mansouri et al.   JOURNAL OF VIROLOGY

Tumultuous Relationship between the Human Immunodeficiency Virus Type 1 Viral Infectivity Factor (Vif) and the Human APOBEC-3G and APOBEC-3F Restriction Factors

(2009) S. Henriet et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses

(2009) Ana-Monica Pais-Correia et al.   NATURE MEDICINE

Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

(2009) Eri Miyagi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration

(2009) R. K. Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

(2009) Kei Sato et al.   Retrovirology

The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

(2009) Amy J Andrew et al.   Retrovirology

Lipids and membrane microdomains in HIV-1 replication

(2009) Abdul A. Waheed et al.   VIRUS RESEARCH

Cell-to-cell HIV-1 spread and its implications for immune evasion

(2009) Nicola Martin et al.   Current Opinion in HIV and AIDS

Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

(2009) Ravindra K. Gupta et al.   PLoS Pathogens

BCA2/Rabring7 Promotes Tetherin-Dependent HIV-1 Restriction

(2009) Kei Miyakawa et al.   PLoS Pathogens

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment

(2008) Michael H. Malim et al.   Cell Host & Microbe

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Inhibition of Lassa and Marburg Virus Production by Tetherin

(2008) T. Sakuma et al.   JOURNAL OF VIROLOGY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Small-molecule inhibition of HIV-1 Vif

(2008) Robin Nathans et al.   NATURE BIOTECHNOLOGY

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY