Non-Steroidal Anti-Inflammatory Drugs and Cognitive Function: Are Prostaglandins at the Heart of Cognitive Impairment in Dementia and Delirium ?

Cyclooxygenase-1 null mice show reduced neuroinflammation in response to β-amyloid

(2016) Sang-Ho Choi et al.   Aging-US

Extended results of the Alzheimer’s disease anti-inflammatory prevention trial

(2011) John C. Breitner et al.   Alzheimers & Dementia

CEREBROSPINAL FLUID INTERLEUKIN-8 LEVELS ARE HIGHER IN PEOPLE WITH HIP FRACTURE WITH PERIOPERATIVE DELIRIUM THAN IN CONTROLS

(2011) Alasdair M.J. MacLullich et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Contribution of systemic inflammation to chronic neurodegeneration

(2010) V. Hugh Perry   ACTA NEUROPATHOLOGICA

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

Effect size of reference memory deficits in the Morris water maze in Tg2576 mice

(2010) Miranda N. Reed et al.   BEHAVIOURAL BRAIN RESEARCH

Cortisol, interleukins and S100B in delirium in the elderly

(2010) Barbara C. van Munster et al.   BRAIN AND COGNITION

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

(2010) Robert Field et al.   BRAIN BEHAVIOR AND IMMUNITY

The Prostaglandin E2 E-Prostanoid 4 Receptor Exerts Anti-Inflammatory Effects in Brain Innate Immunity

(2010) J. Shi et al.   JOURNAL OF IMMUNOLOGY

Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease

(2010) Ruth F. Villarán et al.   JOURNAL OF NEUROCHEMISTRY

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

(2010) Daniel C Lee et al.   Journal of Neuroinflammation

Strain specific differences in memory and neuropathology in a mouse model of Alzheimer's disease

(2010) Kathryn A.C. Glazner et al.   LIFE SCIENCES

Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease

(2010) M. Coma et al.   NEUROBIOLOGY OF DISEASE

Probing the Biology of Alzheimer's Disease in Mice

(2010) Karen H. Ashe et al.   NEURON

A Randomized, Double-blind, Placebo Controlled-trial of Triflusal in Mild Cognitive Impairment

(2009) Teresa Gómez-Isla et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344×BN F1 rats

(2009) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1

(2009) J.L. Teeling et al.   BRAIN BEHAVIOR AND IMMUNITY

Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease

(2009) Mohammed Filali et al.   BRAIN RESEARCH

BGC20-1531, a novel, potent and selective prostanoid EP4receptor antagonist: a putative new treatment for migraine headache

(2009) KA Maubach et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of the hippocampus in mnemonic integration and retrieval: complementary evidence from lesion and inactivation studies

(2009) M. D. Iordanova et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cerebrovascular Cyclooxygenase-1 Expression, Regulation, and Role in Hypothalamic-Pituitary-Adrenal Axis Activation by Inflammatory Stimuli

(2009) B. Garcia-Bueno et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation and Memory: The Role of Prostaglandins

(2009) Amy M. Hein et al.   MOLECULAR NEUROBIOLOGY

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Delirium accelerates cognitive decline in Alzheimer disease

(2009) T. G. Fong et al.   NEUROLOGY

Emerging roles of PGE2 receptors in models of neurological disease

(2009) Katrin Andreasson   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

(2009) Sang-Ho Choi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)

(2008)   ARCHIVES OF NEUROLOGY

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

(2008) Colm Cunningham et al.   BIOLOGICAL PSYCHIATRY

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

(2008) Linda A. Kotilinek et al.   BRAIN

Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

(2008) M. C. Pott Godoy et al.   BRAIN

Malaise in the water maze: Untangling the effects of LPS and IL-1β on learning and memory

(2008) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY

Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection

(2008) Ruth M. Barrientos et al.   BRAIN BEHAVIOR AND IMMUNITY

Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice

(2008) Ann C. McKee et al.   BRAIN RESEARCH

Rofecoxib in Patients with Mild Cognitive Impairment: Further Analyses of Data from a Randomized, Double-Blind, Trial

(2008) Paul Aisen et al.   Current Alzheimer Research

COX-2, but not COX-1, activity is necessary for the induction of perforant path long-term potentiation and spatial learningin vivo

(2008) T. R. Cowley et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Unravelling the pathophysiology of delirium: A focus on the role of aberrant stress responses

(2008) Alasdair M.J. MacLullich et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Time-Course of Cytokines During Delirium in Elderly Patients with Hip Fractures

(2008) Barbara C. Van Munster et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY

PPARγ agonists as therapeutics for the treatment of Alzheimer’s disease

(2008) Gary Landreth et al.   Neurotherapeutics

Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model

(2008) F. Cacucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

(2007) Jing Chen et al.   BRAIN BEHAVIOR AND IMMUNITY

Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury

(2007) Sang-Ho Choi et al.   FASEB JOURNAL

Effects of progesterone administration and APPswe+PSEN1Δe9 mutation for cognitive performance of mid-aged mice

(2007) Cheryl A. Frye et al.   NEUROBIOLOGY OF LEARNING AND MEMORY