Article
Neurosciences
Cindy H. Lee, Kristi L. Bartholomay, Matthew J. Marzelli, Jonas G. Miller, Jennifer L. Bruno, Amy A. Lightbody, Allan L. Reiss
Summary: This study investigated neuroanatomical differences in young females with fragile X syndrome compared to a matched control group. The results showed larger total gray and white matter volumes in girls with fragile X syndrome, as well as differences in specific brain regions. These findings provide insights into the gene-brain-behavior relationships underlying the fragile X syndrome phenotype in females and expand our understanding of the neurodevelopmental mechanisms in this condition.
Article
Multidisciplinary Sciences
Sergio Leonardo Mendes, Walter Hugo Lopez Pinaya, Pedro Mario Pan, Andrea Parolin Jackowski, Rodrigo Affonseca Bressan, Joao Ricardo Sato
Summary: Recently, studies have investigated the neurodevelopment of psychiatric disorders using structural magnetic resonance imaging (sMRI) data. This study explores the reliability and consistency of a model trained on different datasets with varying stages of neurodevelopment and mental health conditions. The models used 3D convolutional neural networks (CNN) to assess autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), brain age, and dimensional psychopathology. Despite demographic and phenotypic differences, the models showed significant age estimations within and between datasets, with moderate to high correlation. The findings provide insights into youth neurodevelopmental structural changes and highlight the importance of less confounded training datasets for model generalization.
SCIENTIFIC REPORTS
(2023)
Article
Pediatrics
Hui Wang, Zeng-Hui Ma, Ling-Zi Xu, Liu Yang, Zhao-Zheng Ji, Xin-Zhou Tang, Jing-Ran Liu, Xue Li, Qing-Jiu Cao, Jing Liu
Summary: This study found that individuals with autism spectrum disorder showed different atypical regional gray matter volumetric changes in childhood, adolescence, and adulthood compared to their typically developing peers, highlighting the importance of considering developmental stages of the brain when exploring brain structural atypicalities in autism.
CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
(2022)
Article
Psychology, Clinical
KangCheng Wang, YuFei Hu, ChaoGan Yan, MeiLing Li, YanJing Wu, Jiang Qiu, XingXing Zhu
Summary: This study investigated the brain morphology of depressed patients using voxel-based morphometry (VBM) and source-based morphometry (SBM) methods, and identified differences between first-episode and recurrent patients. These findings offer a promising multivariate approach for identifying potential neurobiological markers for depression.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Neurosciences
Yashar Zeighami, Mahsa Dadar, Justine Daoust, Melissa Pelletier, Laurent Biertho, Leonie Bouvet-Bouchard, Stephanie Fulton, Andre Tchernof, Alain Dagher, Denis Richard, Alan Evans, Andreanne Michaud
Summary: Individuals with obesity tend to have increased brain age due to poor brain health caused by grey and white matter atrophy. Weight loss and cardiometabolic improvements following bariatric surgery may reverse this condition and improve brain health.
Article
Neurosciences
David Andre Barriere, Arsene Ella, Frederic Szeremeta, Hans Adriaensen, William Meme, Elodie Chaillou, Martine Migaud, Sandra Meme, Frederic Levy, Matthieu Keller
Summary: Using new MRI resources, transient hypertrophies were observed in various brain regions of female mice during gestation and lactation. Highly maternal females exhibited different brain modifications compared to females with lower levels of maternal care.
Article
Psychology, Biological
Gokhan Aydogan, Remi Daviet, Richard Karlsson Linner, Todd A. Hare, Joseph W. Kable, Henry R. Kranzler, Reagan R. Wetherill, Christian C. Ruff, Philipp D. Koellinger, Gideon Nave
Summary: The study investigates the association between polygenic risk scores for risky behavior and variations in grey-matter volume across multiple brain areas, finding that this relationship accounts for approximately 2.2% of the association between genes and behavior.
NATURE HUMAN BEHAVIOUR
(2021)
Review
Clinical Neurology
Haiyang Yu, Duanyong Chen, Hai Jiang, Guangtao Fu, Yuhui Yang, Zhantao Deng, Yuanfeng Chen, Qiujian Zheng
Summary: Spinal cord injury (SCI) can cause changes in brain structure and function. A voxel-based meta-analysis was conducted to identify specific changes in brain gray matter volume (GMV) and white matter volume (WMV) following SCI. The results showed significant GMV loss in the left insula and bilateral thalamus, as well as significant WMV loss in the bilateral corticospinal tract (CST) in SCI patients compared to healthy controls. Higher motor and pinprick scores were associated with greater GMV in the right postcentral gyrus, while a positive relationship was observed between the light touch score and the bilateral postcentral gyrus. These findings suggest that SCI may trigger neurodegeneration changes in the sensory and motor pathways, and that atrophy of the left insula may be related to depression and neuropathic pain in SCI patients. These structural abnormalities could serve as neuroimaging biomarkers for evaluating prognosis and treatment effect, as well as monitoring disease progression.
FRONTIERS IN NEUROLOGY
(2022)
Review
Psychiatry
Carolin Spindler, Louisa Mallien, Sebastian Trautmann, Nina Alexander, Markus Muehlhan
Summary: White matter (WM) alterations are significant in patients with alcohol use disorder (AUD), and these changes may contribute to motor, cognitive, affective, and perceptual impairments. However, further research is needed to understand the variations of WM alterations over the course of the disorder and their reversibility with prolonged abstinence.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychology, Clinical
Tina Meller, Simon Schmitt, Ulrich Ettinger, Phillip Grant, Frederike Stein, Katharina Brosch, Dominik Grotegerd, Katharina Dohm, Susanne Meinert, Katharina Foerster, Tim Hahn, Andreas Jansen, Udo Dannlowski, Axel Krug, Tilo Kircher, Igor Nenadic
Summary: This study found the association between subclinical psychotic-like experiences and brain structural changes, supporting a dimensional model of the neural correlates of symptoms of the psychotic spectrum.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
Tommaso Ballarini, Elizabeth Kuhn, Sandra Roeske, Slawek Altenstein, Claudia Bartels, Friederike Buchholz, Katharina Buerger, Peter Dechent, Laura Dobisch, Michael Ewers, Klaus Fliessbach, Silka Dawn Freiesleben, Ingo Frommann, Tatjana Gabelin, Wenzel Glanz, Doreen Goerss, John Dylan Haynes, Enise I. Incesoy, Daniel Janowitz, Ingo Kilimann, Luca Kleineidam, Xenia Kobeleva, Christoph Laske, Andrea Lohse, Franziska Maier, Matthias H. Munk, Robert Perneczky, Oliver Peter, Josef Priller, Boris-Stephan Rauchman, Nina Roy, Klaus Scheffler, Anja Schneider, Bjorn H. Schott, Annika Spottke, Eike Jakob Sprut, Stefan Teipel, Jens Wiltfang, Steffen Wolfsgruber, Emrah Duezel, Frank Jessen, Michael Wagner
Summary: Previous studies have shown that bilingualism has a protective effect against dementia. This study aimed to investigate the impact of bilingualism at different life stages on cognition and brain structure in older adulthood. The findings revealed that bilingual individuals who used both languages in their early and middle life stages performed better in learning and memory tasks compared to monolinguals. However, there was no significant effect of bilingualism in the old life stage. These results suggest that bilingualism in early life may have a long-lasting protective effect on cognition and shape the brain to sustain cognitive performance in older adulthood.
NEUROBIOLOGY OF AGING
(2023)
Article
Geriatrics & Gerontology
Ryuzo Orihashi, Yoshito Mizoguchi, Yoshiomi Imamura, Shigeto Yamada, Akira Monji
Summary: This study aimed to investigate the association between serum levels of soluble triggering receptor expressed on myeloid cells 2 (sTREM2) and brain volume in older adults. However, the results showed no correlation between serum sTREM2 levels and volume of different brain regions closely related to cognitive function in older adults aged 65 years and above.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Clinical Neurology
Anton Iftimovici, Julie Bourgin, Josselin Houenou, Olivier Gay, Antoine Grigis, Julie Victor, Boris Chaumette, Marie-Odile Krebs, Edouard Duchesnay
Summary: By combining an interpretable supervised model of conversion to psychosis with a brain age predictor, the study demonstrated that inter-regional asynchronous brain maturation underlies the predictive signature of psychosis. Prediction of psychosis onset was effective, with distinct brain regions showing delayed and accelerated maturational patterns.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2023)
Article
Neurosciences
Lihua Luo, Hongwei Wen, Lixin Gao, Rui Li, Shengpei Wang, Zhenchang Wang, Dongmei Li
Summary: This study investigates the morphological brain changes in thyroid-associated ophthalmopathy (TAO) patients using magnetic resonance imaging (MRI) data. The results suggest that there are localized gray matter volume (GMV) alterations among different groups, and these alterations may serve as a potential discriminative pattern to detect clinical phases of TAO at the individual level.
Article
Psychology, Developmental
Harriet Cornwell, Nicola Toschi, Catherine Hamilton-Giachritsis, Marlene Staginnus, Areti Smaragdi, Karen Gonzalez-Madruga, Jack Rogers, Anne Martinelli, Gregor Kohls, Nora Maria Raschle, Kerstin Konrad, Christina Stadler, Christine Freitag, Stephane De Brito, Graeme Fairchild
Summary: There is growing evidence that resilience in youth has a neurobiological basis. This study used data-driven resilience scores based on adversity and psychopathology to investigate associations between resilience and brain structure in youth. The findings suggest that resilience is associated with brain regions involved in executive functioning, emotion regulation, and attention.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Neuroimaging
Anshita Singh, Amit Arya, Vivek Agarwal, Raj Shree, Uttam Kumar
Summary: This study found crucial GM and WM alterations in multiple neural regions in children with bipolar disorder, even during sustained and substantial remission.
BRAIN IMAGING AND BEHAVIOR
(2022)
Article
Dermatology
Rajna Ogrin, Mohammod A. Motin, Behzad Aliahmad, Kylie Elder, Jacinta Anderson, Dinesh Kumar
Summary: This study investigated the effectiveness of using thermal imaging to predict venous leg ulcer healing in the homes of participants. The results showed that thermal imaging could not predict the healing progression of ulcers when taken in home settings.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2023)
Article
Management
Amit Kumar Yadav, Dinesh Kumar
Summary: This paper proposes a lean-agile-green practices approach to improve the efficiency of the vaccine supply chain. A fuzzy decision framework is used to prioritize practices and it is found that sustainable packaging, coordination among supply chain stakeholders, and cold chain technology improvement have the greatest impact on performance indicators. The findings of this study will help policymakers in reframing strategies for a sustainable vaccine supply chain.
INTERNATIONAL JOURNAL OF PRODUCTIVITY AND PERFORMANCE MANAGEMENT
(2023)
Article
Plant Sciences
Kiran Sharma, Rachna Verma, Dinesh Kumar, Eugenie Nepovimova, Kamil Kuca, Ashwani Kumar, Disha Raghuvanshi, Rajni Dhalaria, Sunil Puri
Summary: This study focuses on the usage of different ethnomedicinal plants in the treatment of neurodegenerative diseases in different regions of Himachal Pradesh, India. The study reveals 73 ethnomedicinal plants used for various neurological disorders, with a particular emphasis on plants used for epilepsy. The study also highlights the importance of phytochemicals and their neuroprotective effects in traditional medicine.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Nanoscience & Nanotechnology
M. Lokeshwari, P. Vidya Sagar, K. Dilip Kumar, D. Thirupathy, Ram Subbiah, P. Ganeshan, A. H. Seikh, S. M. A. K. Mohammed, David Christopher
Summary: The tribological properties of hybridized reinforced aluminum matrix composites were optimized using Taguchi and Grey Relational Analysis, where speed and load were found to have a greater impact on wear index and volume loss than the percentage of reinforcements in the composites.
JOURNAL OF NANOMATERIALS
(2022)
Article
Multidisciplinary Sciences
Dinesh Kumar, Frederic Ayant, Kottakkaran Sooppy Nisar, Daya Lal Suthar
Summary: In this article, we introduce the concepts of fractional-order Kober and generalized Weyl q-integrals, as well as present the properties and results of Riemann-Liouville and Weyl fractional q-integral transforms. By specializing variables and parameters, a wide variety of useful basic functions can be obtained.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES
(2023)
Article
Clinical Neurology
Uttam Kumar, Amit Arya, Vivek Agarwal
Summary: This study examines the task-based functional-connectivity in children with attention deficit hyperactive disorder (ADHD), revealing abnormal connectivity patterns in cognitive control tasks. Important regions including right IFG, right SMA, bilateral precentral gyrus, left DLPFC, and left cerebellum showed abnormal connectivity. The study also found a positive correlation between left DLPFC and right IFG.
PSYCHIATRY RESEARCH-NEUROIMAGING
(2022)
Article
Physics, Multidisciplinary
Pranjali Pranjali, Deepak Kumar Tripathi, Anamika Chaturvedi, Ranjan Kumar Singh, Krishna Mohan Poluri, Dinesh Kumar, Anupam Guleria
Summary: This study evaluated the effect of dialysis time on the surface chemistry and MR contrast enhancement properties of GONPs. It was found that prolonged dialysis time significantly decreased the proton relaxivity of GONPs, which correlated with a decrease in the grafting density of surface polymer.
Letter
Psychiatry
Anshita Singh, Amit Arya, Vivek Agarwal, Raj Shree, Uttam Kumar
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Mathematics
Norbert Suedland, Joerg Volkmann, Dinesh Kumar
Summary: Algebraic equations of degree 4 have been solved analytically since Cardano, but the discovery of two algorithms with the same solutions brings a new insight into the solution methods.
ANNALES UNIVERSITATIS PAEDAGOGICAE CRACOVIENSIS-STUDIA MATHEMATICA
(2022)
Article
Mathematics, Applied
Dinesh Kumar, Frederic Yves Ayant, Clemente Cesarano
Summary: In this article, we provide analytical solutions for temperature distribution in a rectangular parallelepiped using a multivariable I-function. The results obtained in this study have a general character and can be used to deduce several known and new results. We also present the special and specific cases of our main findings.
Article
Computer Science, Information Systems
Mohammod Abdul Motin, Nemuel Daniel Pah, Sanjay Raghav, Dinesh Kant Kumar
Summary: This study investigates the voice characteristics of Parkinson's disease (PD) patients using smartphones and machine learning models. The results show that a combination of phonemes can accurately differentiate the voice of PD patients from healthy individuals. These findings have significant implications for clinical assessments and remote monitoring of PD patients' speech impairments.
Article
Mathematics, Interdisciplinary Applications
Dinesh Kumar, Dumitru Baleanu, Frederic Ayant, Norbert Suedland
Summary: In this work, we derived the fractional order q-integrals and q-derivatives for a basic analogue of the Aleph-function with two variables (AFTV). We discussed its related application and the q-extension of the corresponding Leibniz rule. Additionally, we presented two corollaries involving the basic analogue of the I-function with two variables and the basic analogue of the Aleph-function with one variable.
FRACTAL AND FRACTIONAL
(2022)
Proceedings Paper
Materials Science, Multidisciplinary
Sapna Raghav, Pallavi Jain, Dinesh Kumar
Summary: In this study, a surface altered pectin biopolymer with silica-gel and cerium oxide were used for the adsorption of fluoride ions from aqueous systems. The adsorption process was found to be endothermic, spontaneous, and feasible, with strong surface complexation between cerium and silicon with fluoride ions. Surface analysis and FTIR analysis provided further evidence of the involvement of ion-exchange and electrostatic interaction in the adsorption mechanism.
MATERIALS TODAY-PROCEEDINGS
(2022)
Article
Chemistry, Inorganic & Nuclear
Zahir Abbas, Meena Nemiwal, Ankita Dhillon, Dinesh Kumar
Summary: Nowadays, the biogenesis of nanoparticles has become popular for preventing environmental pollution without the need for additional reducing and stabilizing agents. In this study, nickel oxide nanoparticles (NiONPs) were synthesized using Mentha spicata leaves extract through a green method. The synthesized NiONPs were spherical in shape and had a size range of 25-55 nm. These biogenic NiONPs were effectively used as catalysts in the Kumada-Corriu cross-coupling reaction, reducing the reaction time and increasing the product yield. The turnover frequency and rate of reaction were calculated to be 330 s(-1) and 6.6 mol/s, respectively. The kinetics of the Kumada-Corriu cross-coupling reaction were best explained using a second-order kinetics model.
INORGANIC AND NANO-METAL CHEMISTRY
(2022)
