Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model

Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice

(2013) Alejandro Dau et al.   NEUROBIOLOGY OF DISEASE

Calpain and STriatal-Enriched protein tyrosine Phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model

(2012) C. M. Gladding et al.   HUMAN MOLECULAR GENETICS

Striatal-enriched Protein-tyrosine Phosphatase (STEP) Regulates Pyk2 Kinase Activity

(2012) Jian Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Striatal-Enriched Protein Tyrosine Phosphatase Expression and Activity in Huntington's Disease: A STEP in the Resistance to Excitotoxicity

(2011) A. Saavedra et al.   JOURNAL OF NEUROSCIENCE

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease

(2011) Jing Fan et al.   NEUROBIOLOGY OF DISEASE

Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain

(2011) Xiangning Jiang et al.   NEUROSCIENCE LETTERS

NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death

(2010) Ranjana Poddar et al.   JOURNAL OF NEUROCHEMISTRY

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Differential Susceptibility to Excitotoxic Stress in YAC128 Mouse Models of Huntington Disease between Initiation and Progression of Disease

(2009) R. K. Graham et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP

(2009) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Interaction of Postsynaptic Density Protein-95 with NMDA Receptors Influences Excitotoxicity in the Yeast Artificial Chromosome Mouse Model of Huntington's Disease

(2009) J. Fan et al.   JOURNAL OF NEUROSCIENCE

Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia

(2008) Steven P. Braithwaite et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL

Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

(2008) F. X. Soriano et al.   JOURNAL OF NEUROSCIENCE

Polyglutamine-Modulated Striatal Calpain Activity in YAC Transgenic Huntington Disease Mouse Model: Impact on NMDA Receptor Function and Toxicity

(2008) C. M. Cowan et al.   JOURNAL OF NEUROSCIENCE

Neuronal Pentraxins Modulate Cocaine-Induced Neuroadaptations

(2008) A. M. Pacchioni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices

(2008) S.M. Goebel-Goody et al.   NEUROSCIENCE