Understanding cadherin EGF LAG seven-pass G-type receptors

Analysis of common and coding variants with cardiovascular disease in the diabetes heart study

(2014) Jeremy N Adams et al.   Cardiovascular Diabetology

A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1

(2014) Hong-Mei Wang et al.   DIABETOLOGIA

214 Generation of Isogenic Cell Lines to Study a Single Disease Associated Variant at the 1P13 Cad Risk Locus

(2014) David McVey et al.   HEART

Constitutive GαiCoupling Activity of Very Large G Protein-coupled Receptor 1 (VLGR1) and Its Regulation by PDZD7 Protein

(2014) Qiao-Xia Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CELSR2–PSRC1–SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort

(2014) Prathima Arvind et al.   Journal of Cardiology

Celsr3 is required in motor neurons to steer their axons in the hindlimb

(2014) Guoliang Chai et al.   NATURE NEUROSCIENCE

Identification of Novel CELSR1 Mutations in Spina Bifida

(2014) Yunping Lei et al.   PLoS One

Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner

(2014) Y. Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A dual role for planar cell polarity genes in ciliated cells

(2014) C. Boutin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning

(2014) B.-I. Bae et al.   SCIENCE

The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration

(2013) M. Kaucka et al.   CANCER RESEARCH

Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

(2013) Florence Tatin et al.   DEVELOPMENTAL CELL

Atypical Cadherins Celsr1-3 Differentially Regulate Migration of Facial Branchiomotor Neurons in Mice

(2013) Y. Qu et al.   JOURNAL OF NEUROSCIENCE

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Tools for GPCR drug discovery

(2012) Ru Zhang et al.   ACTA PHARMACOLOGICA SINICA

Role of the planar cell polarity gene CELSR1 in neural tube defects and caudal agenesis

(2012) Redouane Allache et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Sling Compared with Plate Osteosynthesis for Treatment of Displaced Midshaft Clavicular Fractures

(2012) Kaisa J Virtanen et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

The Very Large G Protein Coupled Receptor (Vlgr1) in Hair Cells

(2012) Jin-Peng Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A Role for Atypical Cadherin Celsr3 in Hippocampal Maturation and Connectivity

(2012) J. Feng et al.   JOURNAL OF NEUROSCIENCE

GPR56 and the Developing Cerebral Cortex: Cells, Matrix, and Neuronal Migration

(2012) Kathleen Singer et al.   MOLECULAR NEUROBIOLOGY

A Replication Study of GWAS-Derived Lipid Genes in Asian Indians: The Chromosomal Region 11q23.3 Harbors Loci Contributing to Triglycerides

(2012) Timothy R. Braun et al.   PLoS One

Planar cell polarity genes, Celsr1-3, in neural development

(2012) Jia Feng et al.   Neuroscience Bulletin

Planar Cell Polarity Controls Pancreatic Beta Cell Differentiation and Glucose Homeostasis

(2012) Cedric Cortijo et al.   Cell Reports

Behind the scenes of non-nodal MCL: downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 pathway and mutated status of immunoglobulin heavy chain genes

(2011) Ilaria Del Giudice et al.   BRITISH JOURNAL OF HAEMATOLOGY

Genetic Risk Score and Risk of Myocardial Infarction in Hispanics

(2011) Lu Qi et al.   CIRCULATION

Mutations in the planar cell polarity genesCELSR1andSCRIBare associated with the severe neural tube defect craniorachischisis

(2011) Alexis Robinson et al.   HUMAN MUTATION

Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma

(2011) Ole Ammerpohl et al.   INTERNATIONAL JOURNAL OF CANCER

The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling Activity

(2011) Kevin J. Paavola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEST Motif Serine and Tyrosine Phosphorylation Controls Vascular Endothelial Growth Factor Receptor 2 Stability and Downregulation

(2011) R. D. Meyer et al.   MOLECULAR AND CELLULAR BIOLOGY

The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression

(2011) Kevin B.S. Chow et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Multiple ligand-specific conformations of the β2-adrenergic receptor

(2011) Alem W Kahsai et al.   Nature Chemical Biology

Large Scale Association Analysis Identifies Three Susceptibility Loci for Coronary Artery Disease

(2011) Stephanie Saade et al.   PLoS One

Expression of Wnt Signaling Components during Xenopus Pronephros Development

(2011) Bo Zhang et al.   PLoS One

Celsr3 Is Required for Normal Development of GABA Circuits in the Inner Retina

(2011) Alaron Lewis et al.   PLoS Genetics

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

(2010) Dawn M. Waterworth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epidermal Wound Repair Is Regulated by the Planar Cell Polarity Signaling Pathway

(2010) Jacinta Caddy et al.   DEVELOPMENTAL CELL

GPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregation

(2010) Cheng-Chih Hsiao et al.   FEBS LETTERS

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

Wnt/Planar Cell Polarity Signaling Controls the Anterior-Posterior Organization of Monoaminergic Axons in the Brainstem

(2010) A. G. Fenstermaker et al.   JOURNAL OF NEUROSCIENCE

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

(2010) Fadel Tissir et al.   NATURE NEUROSCIENCE

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

(2009) Philippa J. Talmud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Role of the Atypical Cadherin Celsr3 during Development of the Internal Capsule

(2009) L. Zhou et al.   CEREBRAL CORTEX

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse

(2009) Aurélia Ravni et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Large scale replication analysis of loci associated with lipid concentrations in a Japanese population

(2009) K Nakayama et al.   JOURNAL OF MEDICAL GENETICS

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Discovery of New GPCR Biology: One Receptor Structure at a Time

(2009) Michael A. Hanson et al.   STRUCTURE

Structure and Biochemistry of Cadherins and Catenins

(2009) L. Shapiro et al.   Cold Spring Harbor Perspectives in Biology

Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain

(2008) Steffen Runge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol

(2008) Nilesh J. Samani et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination

(2008) S. Li et al.   JOURNAL OF NEUROSCIENCE

LDL-cholesterol concentrations: a genome-wide association study

(2008) Manjinder S Sandhu et al.   LANCET

Crystallizing Thinking about the  2-Adrenergic Receptor

(2008) A. K. Shukla et al.   MOLECULAR PHARMACOLOGY

A crystal clear view of the β2-adrenergic receptor

(2008) Robert J Lefkowitz et al.   NATURE BIOTECHNOLOGY

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

(2008) Danelle Devenport et al.   NATURE CELL BIOLOGY

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Resolving cadherin interactions and binding cooperativity at the single-molecule level

(2008) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Forebrain Wiring: Genetic Dissection Using Conditional Celsr3 Mutant Mice

(2008) L. Zhou et al.   SCIENCE