New insights into the control of neurotrophic growth factor receptor signaling: Implications for nervous system development and repair

Towards Non Invasive Nerve Growth Factor Therapies for Alzheimer's Disease

(2017) Antonino Cattaneo et al.   JOURNAL OF ALZHEIMERS DISEASE

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

(2012) Anne E. Powell et al.   CELL

Neurotrophic factors in combinatorial approaches for spinal cord regeneration

(2012) Julianne McCall et al.   CELL AND TISSUE RESEARCH

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

(2012) Vivian W. Y. Wong et al.   NATURE CELL BIOLOGY

Sprouty4 Is an Endogenous Negative Modulator of TrkA Signaling and Neuronal Differentiation Induced by NGF

(2012) Fernando C. Alsina et al.   PLoS One

Endocytic trafficking of neurotrophins in neural development

(2012) Maria Ascano et al.   TRENDS IN CELL BIOLOGY

Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ER -Positive Breast Cancer

(2011) S. R. Krig et al.   MOLECULAR CANCER RESEARCH

Slitrks as emerging candidate genes involved in neuropsychiatric disorders

(2011) Catia C. Proenca et al.   TRENDS IN NEUROSCIENCES

Down-regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro

(2010) Baofeng Wang et al.   CANCER BIOLOGY & THERAPY

Neuronal intrinsic barriers for axon regeneration in the adult CNS

(2010) Fang Sun et al.   CURRENT OPINION IN NEUROBIOLOGY

Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo

(2010) N. Panagiotaki et al.   DEVELOPMENT

Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1

(2010) Wei Yi et al.   EXPERIMENTAL CELL RESEARCH

Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure

(2010) T. N. Phoenix et al.   GENES & DEVELOPMENT

ProNGF Induces PTEN via p75NTR to Suppress Trk-Mediated Survival Signaling in Brain Neurons

(2010) W. Song et al.   JOURNAL OF NEUROSCIENCE

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Proneurotrophins, Seizures, and Neuronal Apoptosis

(2010) Wilma J. Friedman   NEUROSCIENTIST

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

(2009) Sha Mi et al.   ANNALS OF NEUROLOGY

Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity

(2009) Fei Ye et al.   JOURNAL OF NEURO-ONCOLOGY

Spred1 Is Required for Synaptic Plasticity and Hippocampus-Dependent Learning

(2009) E. Denayer et al.   JOURNAL OF NEUROSCIENCE

LIG Family Receptor Tyrosine Kinase-Associated Proteins Modulate Growth Factor Signals during Neural Development

(2009) Kenji Mandai et al.   NEURON

Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival

(2009) Camilla Holmlund et al.   NEUROPATHOLOGY

The role of neurotrophic factors in nerve regeneration

(2009) Tessa Gordon   Neurosurgical Focus

Disorganized Innervation and Neuronal Loss in the Inner Ear of Slitrk6-Deficient Mice

(2009) Kei-ichi Katayama et al.   PLoS One

Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation

(2009) E. R. Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sprouty proteins, masterminds of receptor tyrosine kinase signaling

(2008) Miguel A. Cabrita et al.   ANGIOGENESIS

Lrig1 Is an Endogenous Inhibitor of Ret Receptor Tyrosine Kinase Activation, Downstream Signaling, and Biological Responses to GDNF

(2008) F. Ledda et al.   JOURNAL OF NEUROSCIENCE

Serum Response Factor Mediates NGF-Dependent Target Innervation by Embryonic DRG Sensory Neurons

(2008) S. Rasika Wickramasinghe et al.   NEURON

GDNF and GFRα: a versatile molecular complex for developing neurons

(2008) Gustavo Paratcha et al.   TRENDS IN NEUROSCIENCES

Encapsulated cell biodelivery of GDNF: A novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease?

(2007) Olle Lindvall et al.   EXPERIMENTAL NEUROLOGY