Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

Growth of Ectopic Dendrites on Cortical Pyramidal Neurons in Neuronal Storage Diseases Correlates with Abnormal Accumulation of GM2 Ganglioside

(2010) Donald A. Siegel et al.   JOURNAL OF NEUROCHEMISTRY

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A

(2009) Barbara Buccinnà et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic Vesicle Docking: Sphingosine Regulates Syntaxin1 Interaction with Munc18

(2009) Paola G. Camoletto et al.   PLoS One

Ceramide-enriched membrane domains—Structure and function

(2008) Yang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Treating lysosomal storage disorders: Current practice and future prospects

(2008) Frances M. Platt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure–function studies associated with cerebellar Purkinje cell degeneration

(2008) Shannon L. Macauley et al.   EXPERIMENTAL NEUROLOGY

Brain lipid composition in grey-lethal mutant mouse characterized by severe malignant osteopetrosis

(2008) Alessandro Prinetti et al.   GLYCOCONJUGATE JOURNAL

Bioactive sphingolipids: metabolism and function

(2008) Nana Bartke et al.   JOURNAL OF LIPID RESEARCH

Lipid content of brain, brain membrane lipid domains, and neurons from acid sphingomyelinase deficient mice

(2008) Federica Scandroglio et al.   JOURNAL OF NEUROCHEMISTRY

Characterization of common SMPD1 mutations causing types A and B Niemann-Pick disease and generation of mutation-specific mouse models

(2008) Iwan Jones et al.   MOLECULAR GENETICS AND METABOLISM

A Fluorescent Glycolipid-Binding Peptide Probe Traces Cholesterol Dependent Microdomain-Derived Trafficking Pathways

(2008) Steffen Steinert et al.   PLoS One

Anomalous Surface Distribution of Glycosyl Phosphatidyl Inositol–anchored Proteins in Neurons Lacking Acid Sphingomyelinase

(2007) Cristian Galvan et al.   MOLECULAR BIOLOGY OF THE CELL