Understanding the pathogenesis of Alzheimer’s disease: will RNA-Seq realize the promise of transcriptomics?

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Disease-specific, neurosphere-derived cells as models for brain disorders

(2010) N. Matigian et al.   Disease Models & Mechanisms

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION

Transcriptome profiling in neurodegenerative disease

(2010) Eliza Courtney et al.   JOURNAL OF NEUROSCIENCE METHODS

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Defining transcribed regions using RNA-seq

(2010) Brian T Wilhelm et al.   Nature Protocols

A cross-laboratory comparison of expression profiling data from normal human postmortem brain

(2010) M. Mistry et al.   NEUROSCIENCE

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments

(2010) Hugues Richard et al.   NUCLEIC ACIDS RESEARCH

3′-End Sequencing for Expression Quantification (3SEQ) from Archival Tumor Samples

(2010) Andrew H. Beck et al.   PLoS One

Most “Dark Matter” Transcripts Are Associated With Known Genes

(2010) Harm van Bakel et al.   PLOS BIOLOGY

Deconstructing the Dogma

(2009) John S. Mattick   Annals of the New York Academy of Sciences

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization

(2009) Alexandre Ho-Pun-Cheung et al.   BMC MOLECULAR BIOLOGY

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

(2009) Frank Soldner et al.   CELL

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Hyperphosphorylated Tau in the Occipital Cortex in Aged Nondemented Subjects

(2009) Maria Pikkarainen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects

(2009) T. L. Falzone et al.   JOURNAL OF NEUROSCIENCE

pH measurement as quality control on humanpost mortembrain tissue: a study of the BrainNet Europe consortium

(2009) C. M. Monoranu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transcriptome analysis by strand-specific sequencing of complementary DNA

(2009) Dmitri Parkhomchuk et al.   NUCLEIC ACIDS RESEARCH

A Cross-Study Transcriptional Analysis of Parkinson's Disease

(2009) Greg T. Sutherland et al.   PLoS One

Differences in human and chimpanzee gene expression patterns define an evolving network of transcription factors in brain

(2009) Katja Nowick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A global view of genomic information – moving beyond the gene and the master regulator

(2009) John S. Mattick et al.   TRENDS IN GENETICS

Presynaptic translation: stepping out of the postsynaptic shadow

(2009) Michael Akins   Frontiers in Neural Circuits

An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data

(2009) Daniel Ramsköld et al.   PLoS Computational Biology

Molecular genetics of Alzheimer's disease: An update

(2008) Nathalie Brouwers et al.   ANNALS OF MEDICINE

Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis

(2008) Ryan Lister et al.   CELL

Promotion of BACE1 mRNA Alternative Splicing Reduces Amyloid β-Peptide Production

(2008) Karen R. Mowrer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal gene expression correlates of Parkinson's disease with dementia

(2008) Chelsea Stamper et al.   MOVEMENT DISORDERS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Stem cell transcriptome profiling via massive-scale mRNA sequencing

(2008) Nicole Cloonan et al.   NATURE METHODS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Boosting T-cell immunity as a therapeutic approach for neurodegenerative conditions: The role of innate immunity

(2008) M. Schwartz et al.   NEUROSCIENCE

Local Gene Expression in Axons and Nerve Endings: The Glia-Neuron Unit

(2008) Antonio Giuditta et al.   PHYSIOLOGICAL REVIEWS

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

(2008) Patrick M. Loerch et al.   PLoS One

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antisense Transcriptomes of Human Cells

(2008) Yiping He et al.   SCIENCE

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE

Transcriptome content and dynamics at single-nucleotide resolution

(2008) Nicole Cloonan et al.   GENOME BIOLOGY

Comparison of RNA amplification methods and chip platforms for microarray analysis of samples processed by laser capture microdissection

(2007) Elena Caretti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING

Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia

(2007) Vahram Haroutunian et al.   NEUROBIOLOGY OF AGING