Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models

Novel HSP90 Inhibitor NVP-HSP990 Targets Cell-Cycle Regulators to Ablate Olig2-Positive Glioma Tumor-Initiating Cells

(2013) J. Fu et al.   CANCER RESEARCH

Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis

(2013) Daniela A. Bota et al.   JOURNAL OF NEUROSURGERY

High Expression of Heat Shock Protein 90 Is Associated with Tumor Aggressiveness and Poor Prognosis in Patients with Advanced Gastric Cancer

(2013) Jiahong Wang et al.   PLoS One

Cellular Redox Modulator, ortho Mn(III) meso-tetrakis(N-n-Hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP5+ in the Treatment of Brain Tumors

(2012) Stephen T. Keir et al.   Anti-Cancer Agents in Medicinal Chemistry

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth

(2012) K Di et al.   ONCOGENE

Regulation of Embryonic Stem Cell Pluripotency by Heat Shock Protein 90

(2012) Eric Bradley et al.   STEM CELLS

Heat shock protein 90 inhibition: rationale and clinical potential

(2012) Robert B. Den et al.   Therapeutic Advances in Medical Oncology

Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

(2011) Thomas De Raedt et al.   CANCER CELL

Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer

(2011) M. Scaltriti et al.   MOLECULAR CANCER THERAPEUTICS

Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy

(2011) X. Gong et al.   NEUROLOGY

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

(2010) G. Roue et al.   BLOOD

The Pathobiology of Glioma Tumors

(2009) Candece L. Gladson et al.   Annual Review of Pathology-Mechanisms of Disease

Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer

(2008) Dongweon Song et al.   MOLECULAR CANCER THERAPEUTICS

Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells

(2008) Claire Marie-Elisabeth Sauvageot et al.   NEURO-ONCOLOGY

17-AAG sensitized malignant glioma cells to death-receptor mediated apoptosis

(2008) Markus David Siegelin et al.   NEUROBIOLOGY OF DISEASE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma

(2008) Francesca Pistollato et al.   STEM CELLS